Zeinab A. Afify

Zeinab A. Afify, MD

Languages spoken: Arabic, English

Academic Information

Departments Adjunct - Pediatrics

Dr. Afify received her medical degree from University of Alexandria, Egypt, Faculty of Medicine. She completed her Pediatric residency and Pediatric Hematology Oncology fellowship in Riley Hospital for Children, Indiana University.

She was on the faculty in the department of Pediatrics in Alexandria University for 10 years. She also took clinical appointments in Australia and in United Kingdom.

Since 2002 Dr. Afify has been faculty member of the department of Pediatrics, Division of Pediatric Hematology Oncology at the University of Utah and is in is currently an Associate Professor. Dr. Afify is board-certified in Pediatrics and Pediatric Hematology Oncology.

Her clinical and research interests include Pediatric Non-Hodgkin’s lymphoma and post solid organ transplant lymphoproliferative disease (PTLD). She is an a member of the Editorial Board American Academy of Pediatrics (AAP). PREP Hematology Oncology Section and member of Leukemia/Lymphoma/lymphoproliferative Work Group. American Academy of Pediatrics (AAP) and American Society of Pediatric Hematology Oncology (ASPHO) policy Group.

Research Statement

My Academic and research interests are focused on pediatric non-Hodgkin lymphoma (NHL) and post solid organ transplant lymphoproliferative disease (PTLD). I am a member and coinvestigator in Children’s Oncology Group (COG) NHL committee, a past coinvestigator on 2 past clinical trials and 2 currently in development. I am currently leading a multi institutional study of monomorphic PTLD. Three subtypes o PTLD are understudy, Burkitt lymphoma occuring in the setting of PTLD, EBV negative monomorphic PTLD/diffuse large B cell lymphoma (DLBCL) and central nervous system positive PTLD.

Education History

Professional Medical University of Alexandria
 MBBCh
Internship University of Alexandria Hospitals
 Intern
Residency University of Alexandria Children's Hospital
 Resident
Research Fellow Emory University School of Medicine
 Research Fellow
Fellowship University of Iowa Hospitals and Clinics
 Clinical Fellow
Fellowship Riley Hospital for Children
 Fellow
Residency Riley Hospital for Children
 Resident
Fellowship Children's Hospital of Westmead
 Clinical Fellow

Selected Publications

Journal Article

  1. Giulino-Roth L, O'Donohue T, Chen Z, Bartlett NL, LaCasce A, Martin-Doyle W, Barth MJ, Davies K, Blum KA, Christian B, Casulo C, Smith SM, Godfrey J, Termuhlen A, Oberley MJ, Alexander S, Weitzman S, Appel B, Mizukawa B, Svoboda J, Afify Z, Pauly M, Dave H, Gardner R, Stephens DM, Zeitler WA, Forlenza C, Levine J, Williams ME, Sima JL, Bollard CM, Leonard J (2017). Outcomes of adults and children with primary mediastinal B-cell lymphoma treated with dose-adjusted EPOCH-R. British journal of haematology, 179(5), 739-747. (Read full article)
  2. Iglesias Cardenas F, Agarwal AM, Vagher J, Maese L, Fluchel M, Afify (2021). Two Clonally Distinct B-Cell Lymphomas Reveal the Diagnosis of XLP1 in a Male Child and His Asymptomatic Male Relatives: Case Report and Review of the Literature. Journal of pediatric hematology/oncology, 43(8), e1210-e1213. (Read full article)
  3. Bruggers CS, Bleyl SB, Pysher T, Barnette P, Afify Z, Walker M, Biegel J (2011). Clinicopathologic comparison of familial versus sporadic atypical teratoid/rhabdoid tumors (AT/RT) of the central nervous system. Pediatric blood & cancer, 56(7), 1026-31. (Read full article)

Case Report

  1. Zhou, D., Paxton, C.N., Kelley, T.W., Afify, Z., South, S.T., Miles, R.R. (2016). Two Unrelated Burkitt Lymphomas Seven Years Apart in a Patient With X-Linked Lymphoproliferative Disease Type 1 (XLP1). Am J Clin Pathol, 146(2), 248-53. (Read full article)
  2. Cole, B., Zhou, H., McAllister, N., Afify, Z., Coffin, C.M. (2006). Inflammatory myofibroblastic tumor with thrombocytosis and a unique chromosomal translocation With ALK rearrangement. Arch Pathol Lab Med, 130(7), 1042-5. (Read full article)
  3. Niazi TN, Forester C, Afify Z, Riva-Cambrin (2009). Osteosarcoma presenting as hemorrhagic cerebellar metastasis. Child's nervous system, 25(12), 1643-7. (Read full article)
  4. Gallagher-Lacey C, Afify Z, Yaish HM, Yoder BA, Christensen R (2017). An Instructive Case of Transient Myeloproliferative Disorder. Clinical pediatrics, 56(3), 288-289. (Read full article)
  5. Carter-Febres M, Smock KJ, Ware AL, Afify Z (2020). Improvement of Bleeding Manifestations of Acquired Von Willebrand Syndrome after Balloon Aortic Valvoplasty in a child with Aortic Stenosis. https://doi.org/10.1016/j.ppedcard.2020.101334. Progress in pediatric cardiology,
  6. Miles RR, Afify Z, Yaish H, Perkins S (2010). CD56-negative extranodal nasal type NK/T-cell lymphoma. Pediatric blood & cancer, 55(1), 186-9. (Read full article)
  7. Meznarich J, Miles R, Paxton CN, Afify (2016). Pediatric B-Cell Lymphoma With Lymphoblastic Morphology, TdT Expression, MYC Rearrangement, and Features Overlapping With Burkitt Lymphoma. Pediatric blood & cancer, 63(5), 938-40. (Read full article)

Letter

  1. Febres MC, Viskochil D, Rampton J, Afify (2020). Further Lessons Learned From a Child With NF1 and Classical Hodgkin Lymphoma. Journal of pediatric hematology/oncology, 43(5), e743-e744. (Read full article)
  2. Carter Febres M, Abbott J, Cipriano SD, Knackstedt ED, George TI, Afify (2021). Drug reaction with eosinophilia and systemic symptoms (DRESS)-associated hemophagocytic lymphohistiocytosis (HLH), an important and underrecognized HLH mimic: A case report. Pediatric blood & cancer, 68(2), e28657. (Read full article)

Abstract

  1. Afify Z, Khatib F, Bener A, Castella (2001). Clinical and Epidemiological Features of Pediatric Hodgkin's Disease in the United Arab Emirates (UAE). Presented at the SIOP Meeting, October. Medical and pediatric oncology, 37(3), 293.
  2. Afify Z, Raaschou T, Castella A, Kristensen J, Zwaan (2001). Familial Hodgkin's Disease in Three Full Siblings. Presented at the SIOP Meeting, October. Medical and pediatric oncology, 37(3), 313.
  3. Hesketh E, Shaw P, Afify Z, Gilbert L, Ratnamoham, Burgess (2001). A Cross Sectional Study to Look at Parvovirus B19 Infection in Children with Acute Lymphoblastic Leukemia. Presented at the SIOP Meeting, October, by Dr. Hesketh. Medical and pediatric oncology, 37(3), 262.
  4. Afify Z, Jacobsz A, Matta H, Khatib (2001). Surgical Emergencies in Pediatric Burkitt's Lymphoma. Presented at the IPSO Meeting, October. Medical and pediatric oncology, 37(3), 341.
  5. Trad O, Jumaa P, Afify (2000). The Changing Pattern of Organisms Isolated from Blood cultures in Pediatric Oncology Patients in the United Arab Emirates. International Society of Pediatric Oncology (SIOP) meeting, Amsterdam, Holland. Medical and pediatric oncology, 37(3), 313.
  6. Miles RR, Afify Z, yaish H, Perkins (2009). CD56-Negative extranodal NK/T-cel Lymphoma, Nasal Type, in a Pediatric Patient: A case Report, Proceedings of the Third international Meeting on Pediatric and adolescent Non-Hodgkin's Lymphoma, Frankfurt, Germany. 3(5), 118.
  7. Meyers R, Afify (2010). Retroperitoneal Kaposiform Hemangioendothelioma: Review of the medical literature and surgical management options International Society of Pediatric Oncology SIOP 42nd Congress Boston, MA. 55(5), 904.
  8. Meyers R, Afify (2010). Outcome of Relapsed mature B-Cell Non-Hodgkin's Lymphoma. International Society of Pediatric Oncology SIOP 42nd Congress Boston, MA. 55(5), 869.
  9. Whipple N, Afify Z, Schiffman J, Bruggers (2012). Extra-Gonadal Familial Germ Cell Tumors in Two male Children. American Society of Pediatric Hematology/Oncology 25th Annual Meeting, New Orleans, LA. 58(7), 1071.
  10. Bruggers C, Afify Z, Levin (2012). Impact of Osteonecrosis on Quality of Life in Survivors of Childhood Acut Lymphoblastic Leukemia. American Society of Pediatric Hematology/Oncology 25th Annual Meeting, New Orleans, LA. 58(7), 1091.
  11. Afify Z, Barnhart (2012). Role of Second Look Surgery in Residual Abdominal Mass in mature B-Cell Non-Hodgkin's Lymphoma in children. Fourth International Symposium for Children and Adolescent Non-Hodgkin's Lymphoma, New York, NY. 159(Suppl), 72.
  12. Ampofo K, Korgensk K, Meyers (2014). International Society of Pediatric Oncology SIOP 46th Congress Toronto, Canada. 61(S2),
  13. Afify Z, Lobb R, Feola (2005). Experience with Arm Ports in Pediatric Patients with Hematological and Oncological disorders in a Single Institution. SIOP meeting vancouver, Canada. 45(4), 512.
  14. Bruggers C, Barentte P, Pysher T, Afify Z, Walker M, Bleyl S, Biegel (2009). Clinicopathologic Comparison of Familial versus Sporadic Atypical Teratoid/Rhabdoid Tumors (AT/RT) of the Central Nervous System: the Utah experience. American Society of Pediatric Hematology Oncology (ASPHO) annual meeting. 52(6), 733.
  15. Afify Z, Ampofo K, Korgensk (2005). The Expanding Spectrum of central Venous Catheter Related Infection by Non-Tuberculous Mycobacteria in Immunocompromised Children with Cancer. SIOP meeting Vancouver, Canada. 45(4), 512.
  16. Afify Z, Bruggers C, Barnette P, Book L, Perkins (2009). Post Organ Transplantation Lymphoproliferative disease (PTLD). A Single Institution Experience. Proceedings of the Third international Meeting on Pediatric and Adolescent Non-Hodgkin's Lymphoma, Frankfurt Germany. 3(5), 154.
  17. Afify Z, Barnette P, Yaish H, Perkins (2009). Clinical Features and Outcome of Recurrent Anaplastic Large Cell Lymphoma (ALCL) In Children and Adolescents. Proceedings of the Third international Meeting on pediatric and Adolescent Non-Hodgkin's Lymphoma, Frankfurt, Germany. 3(5), 96.