Academic Information
Departments: Pathology - Professor
Divisions: Microbiology and Immunology
Academic Office Information
(801) 587-3035
Pathology
1950 Circle of Hope, Room: HCI South 3707
Salt Lake City, UT 84112
Labs
Research Interests
- Gene Regulation
- Development and Regulation of Immune Responses
- Stem Cells
- Transcriptional Control of Malignant State
Dean Tantin is a Professor in the Department of Pathology at the University of Utah and a member of the Nuclear Control of Cell Growth and Differentiation Program at Huntsman Cancer Institute.
Tantin studies the regulation of gene expression and its relationship to immune and stem cell function, and malignancy. He focuses on a class of transcription factors that has been tied to cellular reprogramming and immune function. Examples of these proteins are Oct1/Pou2f1, Oct2/Pou2f1, and Oct4/Pou5f1. These proteins regulate cellular physiology and differentiation state through control of metabolism and through control of poised (silent but readily inducible) gene expression states. They interact with multiple cofactors that control local chromatin and gene expression.
Tantin received a B.S. in Molecular Biology from the University of California, San Diego and a Ph.D. from the UCLA Molecular Biology Interdepartmental Ph.D. program. He was a Postdoctoral Fellow at the Massachusetts Institute of Technology Center for Cancer Reseach and Department of Biology under Nobel Laureate Phil Sharp.
Education History
| Postdoctoral Fellowship |
Massachusetts Institute of Technology Center for Cancer Research |
Postdoctoral Fellow |
|---|---|---|
| Postdoctoral Training |
Massachusetts Institute of Technology Center for Cancer Research |
Postdoctoral Associate |
| Postdoctoral Fellowship |
Massachusetts Institute of Technology, Center for Cancer Research Immunology |
Postdoctoral Fellow |
| Doctoral Training |
University of California, Los Angeles, Molecular Biology Institute Interdepartmental Ph.D. Program Molecular Biology |
Ph.D. |
| Undergraduate |
University of California, San Diego Division of Biology Molecular Biology |
B.S. |