Biochemistry

In the Biochemistry Department, we are a vigorous group of scientists and trainees dedicated to the expansion and transmission of knowledge about the biological world. Our particular focus is the characterization of macromolecules and biological processes at the molecular level. Research groups in the department address the structure of biological macromolecules, the mechanisms by which they function, and the possible applications to research technology and to medicine.

Latest News

A Molecular Noose Caught in the Act
Research
Dec 03, 2015

A Molecular Noose Caught in the Act

One of the most fundamental challenges that a cell faces is how to bring membranes that are far apart, close together. New research in Science shows how cellular machinery, called ESCRT (Endosomal Sorting Complexes Required for Transport), accomplishes this essential task. ... Read More

Biochemistry
A Call for Caution Before Genetically Engineering Humans
Research, Education
Mar 19, 2015

A Call for Caution Before Genetically Engineering Humans

genetic engineering, genetics

A group of 18 leaders in the field of genomic engineering have written a perspective to be published in the journal Science Express on March 19, cautioning fellow scientists from going down this path too quickly. They call for a moratorium on genetically engineering changes in human DNA that would be passed to future generations. Before this can happen, they say, scientists, clinicians, and the general public must agree on the best ways to ensure the safety and efficacy of the technology. ... Read More

Biochemistry
Novel
Research
Feb 09, 2015

Novel "Smart" Insulin Automatically Adjusts Blood Sugar in Diabetic Mouse Model

diabetes, insulin

Scientists have created a novel, long-lasting "smart" insulin that self-activates when blood sugar soars. Tests on mouse models for type 1 diabetes show that one injection works for a minimum of 14 hours, during which it can repeatedly and automatically lower blood sugar levels after simulated meals, mimicking blood sugar recovery in healthy mice. The finding represents an important advance in insulin therapy for diabetics and will be published Feb. 9 in PNAS Early Edition.... Read More

Biochemistry

Faculty Spotlight

The Rutter Laboratory is currently exploring three areas. While distinct, these programs are all centered upon cellular metabolic homeostasis—the concept that cells must constantly monitor their nutrient, metabolic and hormonal environments and adjust their behavior accordingly.


Functional Annotation of the Mitochondrial Proteome



Metabolic underpinnings of cancer and stem cells



Integrated Control of Metabolism by PASK-dependent Signaling


More about Rutter Lab research...

The Rutter Laboratory is currently exploring three areas. While distinct, these programs are all centered upon cellular metabolic homeostasis—the concept that cells must constantly monitor their nutrient, metabolic and hormonal environments and adjust their behavior accordingly.

  1. Functional Annotation of the Mitochondrial Proteome

  2. Metabolic underpinnings of cancer and stem cells

  3. Integrated Control of Metabolism by PASK-dependent Signaling

More about Rutter Lab research...

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