International Head and Neck Cancer Epidemiology Consortium (INHANCE)
The In ternational H ead and N eck C ancer E pidemiology (INHANCE) Consortium is a collaboration of research groups leading large molecular epidemiology studies of head and neck cancer (oral cavity, oropharynx, hypopharynx and larynx).
Questionnaire data on over 26,600 cases & 37,900 controls, and biological samples from a majority of the study population were collected. These studies have been conducted in various regions of the world. More details.
We aim to improve the understanding of the causes and mechanisms of head and neck cancer.
INHANCE Recent Publications
Aspirin intake and head and neck cancer: A pooled analysis within the INHANCE consortium. Sassano M, Taborelli M, Boccia S, Cadoni G, La Vecchia C, Garavello W, Lazarus P, Lee YA, Hashibe M, Boffetta P.Head Neck. 2024 Jan 16. doi: 10.1002/hed.27638. Online ahead of print. PMID: 38229229.
Risk factors for head and neck cancer in more and less developed countries: Analysis from the INHANCE Consortium. Goyal N, Hennessy M, Lehman E, Lin W, Agudo A, Ahrens W, Boccia S, Brennan P, Brenner H, Cadoni G, Canova C, Chen C, Conway D, Curado MP, Dal Maso L, Daudt AW, Edefonti V, Fabianova E, Fernandez L, Franceschi S, Garavello W, Gillison M, Hayes RB, Healy C, Herrero R, Holcatova I, Kanda JL, Kelsey K, Hansen BT, Koifman R, Lagiou P, La Vecchia C, Levi F, Li G, Lissowska J, Mendoza López R, Luce D, Macfarlane G, Mates D, Matsuo K, McClean M, Menezes A, Menvielle G, Morgenstern H, Moysich K, Negri E, Olshan AF, Pandics T, Polesel J, Purdue M, Radoi L, Ramroth H, Richiardi L, Schantz S, Schwartz SM, Serraino D, Shangina O, Smith E, Sturgis EM, Świątkowska B, Thomson P, Vaughan TL, Vilensky M, Winn DM, Wunsch-Filho V, Yu GP, Zevallos JP, Zhang ZF, Zheng T, Znaor A, Boffetta P, Hashibe M, Lee YA, Muscat JE. Oral Dis. 2023 May;29(4):1565-1578. doi: 10.1111/odi.14196. Epub 2022 Apr 8. PMID: 35322907.
Plasma miR-151-3p as a Candidate Diagnostic Biomarker for Head and Neck Cancer: A Cross-sectional Study within the INHANCE Consortium. Pastorino R, Sassano M, Danilo Tiziano F, Giraldi L, Amore R, Arzani D, Abiusi E, Ahrens W, Vilches LA, Canova C, Healy CM, Holcatova I, Lagiou P, Polesel J, Popovic M, Nygård S, Cadoni G, Znaor A, Boffetta P, Matsuo K, Oze I, Brennan P, Boccia S.Cancer Epidemiol Biomarkers Prev. 2022 Dec 5;31(12):2237-2243. doi: 10.1158/1055-9965.EPI-22-0376. PMID: 36126276.
Infection with Human Papilloma Virus (HPV) and risk of subsites within the oral cancer. Giraldi L, Collatuzzo G, Hashim D, Franceschi S, Herrero R, Chen C, Schwartz SM, Smith E, Kelsey K, McClean M, Gillison M, Boccia S, Hashibe M, Amy Lee YC, Boffetta P. Cancer Epidemiol. 2021 Dec;75:102020. doi: 10.1016/j.canep.2021.102020. Epub 2021 Sep 9. PMID: 34509873.
Occupational socioeconomic risk associations for head and neck cancer in Europe and South America: individual participant data analysis of pooled case-control studies within the INHANCE Consortium. Conway DI, Hovanec J, Ahrens W, Ross A, Holcatova I, Lagiou P, Serraino D, Canova C, Richiardi L, Healy C, Kjaerheim K, Macfarlane GJ, Thomson P, Agudo A, Znaor A, Brennan P, Luce D, Menvielle G, Stucker I, Benhamou S, Ramroth H, Boffetta P, Vilensky M, Fernandez L, Curado MP, Menezes A, Daudt A, Koifman R, Wunsch-Filho V, Yuan-Chin AL, Hashibe M, Behrens T, McMahon AD. J Epidemiol Community Health. 2021 Aug;75(8):779-787. doi: 10.1136/jech-2020-214913. Epub 2021 Feb 23. PMID: 33622804; PMCID: PMC8292575.
Lessons learned from the INHANCE consortium: An overview of recent results on head and neck cancer. Bravi F, Lee YA, Hashibe M, Boffetta P, Conway DI, Ferraroni M, La Vecchia C, Edefonti V; INHANCE Consortium investigators. Oral Dis. 2021 Jan;27(1):73-93. doi: 10.1111/odi.13502. Epub 2020 Jul 16. PMID: 32569410; PMCID: PMC7752834.