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(last updated April 29, 2024)


Meetings & telephone conferences
1st meeting in Orlando, FL (March 30, 2004):
Agenda and Participants / Minutes 

2nd meeting in Seattle, WA (February 10-11, 2005):
Agenda Participants Minutes / Slides ( 6 slides/page or 2 slides/page ) / Group picture 

3rd meeting in Bethesda, MD (January 19, 2006)
Agenda Participants Minutes Slides Handouts Group picture 

4th meeting at IARC, Lyon, France (January 18-19, 2007)
Agenda Participants Minutes / Slides ( 6 slides or 2 slides ) / Handouts Authorship guideline draft Group picture 

5th meeting at MD Anderson Cancer Center, Houston, Texas (February 20, 2008)
Agenda and Participants Minutes Slides (15MB)Group picture 

6th meeting at INSERM, Paris, France (March 24-25, 2009)
Agenda and Participants Minutes Slides (5MB) Group picture 

7th Annual INHANCE Meeting at NCI, Bethesda, MD, USA (April 21-22, 2010)
Agenda Participants Minutes Slides (2MB) Group picture 

8th Annual INHANCE Meeting at Mount Sinai School of Medicine, New York City (March 22, 2011)
Agenda Participants Minutes Slides (4MB) Group picture 

9th Annual INHANCE Meeting at Mario Negri, Milan, Italy (May 2, 2012)
Agenda Participants Minutes Slides (9MB) Group picture 

10th Annual INHANCE Meeting at Mount Sinai, New York, NY USA (May 8, 2013)
Agenda Participants Minutes Slides (7.5MB)Group picture 

11th Annual INHANCE Meeting at Universita Cattolica Del Sacro Cuore, Rome, Italy (June 4, 2014)
Agenda Participants Minutes Slides (7.2MB) Group picture 

12th Annual INHANCE Meeting at Mount Sinai New York Eye and Ear Infirmary, New York, NY, USA (May 29, 2015)
Agenda Participants Minutes Slides (4.39MB) Group picture

13th Annual INHANCE Meeting at Curie Institute, Paris, France (June 3, 2016)
Agenda Participants Minutes Slides (9.02MB) Group picture 

14th Annual INHANCE Meeting at Mount Sinai, New York City, USA (May 26, 2017)
Agenda Participants Minutes (updated on July 5, 2017!) Slides (10MB) Group picture Group dinner picture 

15th Annual INHANCE Meeting at University of Milan, Milan, Italy (June 29, 2018)
Agenda Participants Minutes Slides (18MB) Group picture Group dinner picture 

16th Annual INHANCE Meeting at Mt. Sinai, New York City, USA (April 12, 2019)
Agenda Participants Minutes Slides (4MB) Group picture Group dinner picture 

2020 Annual INHANCE Meeting on zoom (November 18, 2020)
Agenda Participants Minutes / Slides  / Group picture 

2021 Annual INHANCE Meeting on zoom (May 11, 2021)
Agenda Participants Minutes / Slides  / Group picture 

2022 Annual INHANCE Meeting on zoom (September 16, 2022)
Agenda Participants Minutes / Slides  / Group picture

2023 Annual INHANCE Meeting on zoom (October 6, 2023)
Agenda Participants Minutes / Slides  /Group picture 
2024 Annual INHANCE Meeting at UCLA, Los Angeles, USA (April 11, 2024)
Agenda Minutes / Slides (Morning)  , Slides (Keynote) , Slides (Afternoon 1)  , Slides (Afternoon 2)  /Group picture 1 ,Group picture 2

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Executive Committee
Telephone conference minutes
July 2006 December 2006 April 2007 July 2007 July 2008 October 2008 / May 2010 October 2010 February 2011 April 2011 February 2012 
April 2012 June 2012 October 2012 March 2013 November 2013 March 2014 March 2016 December 2016 March 2018 October 2018 January 2019 
November 2021

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Other documents

INHANCE Consortium Guidelines 

INHANCE Publication Guidelines 

Head & Neck Cancer Classification Criteria (Wei) 

ICD-O-2 Classification (Boffetta) 

Analysis proposal form  (updated on Nov. 2021)

INHANCE data dictionary, v1.6 

Pooling methods, v1.6 

INHANCE follow-up data dictionary (updated on Oct. 2021)

Pooling methods for follow-up studies  (updated on Oct. 2021)

INHANCE application form 2012 

References for INHANCE studies (in Reference Manager format - .zip)

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  • Please download the excel file with tables for study summary, study design, questionnaire information, and biological samples
Questionnaires and representative publications from consortium studies 
Study no Questionnaire Publication Questionnaire for follow-up studies Publication for follow-up studies
1 Milan (1984-1989)  Franceschi S, Talamini R, Barra S, et al. Smoking and drinking in relation to cancers of the oral cavity, pharynx, larynx, and esophagus in northern Italy. Cancer Res.1990;50:6502-7     
2 Aviano  Negri E, La Vecchia C, Franceschi S, Tavani A. Attributable risk for oral cancer in northern Italy. Cancer Epidemiol Biomarkers Prev.1993;2:189-93.     
3 France (1987-1992)  Benhamou S, Tuimala J, Bouchardy C, Dayer P, Sarasin A, Hirvonen A. DNA repair gene XRCC2 and XRCC3 polymorphisms and susceptibility to cancers of the upper aerodigestive tract. Int J Cancer. 2004 Dec 10;112(5):901-4.     
4 Italy Multicenter  Bosetti C, Gallus, S, Trichopoulou A, Talamini R, Franceschi S, Negri E, et al. Influence of the Meditterranean diet on the risk of cancers of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev.2003; 12: 1091-4.     
5 Switzerland  Levi F, Pasche C, La Vecchia C, et al. Food groups and risk of oral and pharyngeal cancer. Int J Cancer 1998;77:705-9.     
6 Central Europe  Hashibe M, Boffetta P, Zaridze D, Shangina O, Szeszenia-Dabrowska N, Mates D, Janout V, Fabiánová E, Bencko V, Moullan N, Chabrier A, Hung R, Hall J, Canzian F, Brennan P. Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev. 2006;15:696-703.     
7 NY Multicenter (AHF)  Muscat JE, Richie JP Jr., Thompson S, Wynder EL. Gender differences in smoking and risk for oral cancer. Cancer Res.1996;56:5192-97.     
8 Seattle (1985-1995)  Rosenblatt KA, Daling JR, Chen C, Sherman KJ, Schwartz SM. Marijuana use and risk of oral squamous cell carcinoma. Cancer Res.2004;64:4049-54.     
9 Iowa  Smith EM, Hoffman HT, Summersgill KS, Kirchner HL, Turek LP, Haugen TH. Human papillomavirus and risk of oral cancer. Laryngoscope.1998;108:1098???¡V103.     
10 North Carolina (1994-1997)  Olshan AF, Weissler MC, Watson MA, Bell DA. GSTM1, GSTT1, GSTP1, CYP1A1, and NAT1 polymorphisms, tobacco use, and the risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev.2000;9:185-91.     
11 Tampa  Elahi A, Zheng Z, Park J, Eyring K, McCaffrey T, Lazarus P. The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk. Carcinogenesis.2002;23:1229-34.     
12 Los Angeles  Cui Y, Morgenstern H, Greenland S, et al. Polymorphism of xeroderma pigmentosum group G and the risk of lung cancer and squamous cell carcinomas of the oropharynx, larynx and esophagus. Int J Cancer.2006;118:714-20.     
13 Houston  Zhang Z, Shi Q, Liu Z, Sturgis EM, Spitz MR, Wei Q. Polymorphisms of methionine synthase and methionine synthase reductase and risk of squamous cell carcinoma of the head and neck: a case-control analysis. Cancer Epidemiol Biomarkers Prev.2005;14:1188-93.     
14 Puerto Rico  Hayes RB, Bravo-Otero E, Kleinman DV, et al. Tobacco and alcohol use and oral cancer in Puerto Rico. Cancer Causes Control.1999;10:27-33.     
15 Latin America  Szymańska K, Hung RJ, Wünsch-Filho V, Eluf-Neto J, Curado MP, Koifman S, Matos E, Menezes A, Fernandez L, Daudt AW, Boffetta P, Brennan P. Alcohol and tobacco, and the risk of cancers of the upper aerodigestive tract in Latin America: a case-control study. Cancer Causes Control.2011;22:1037-46.     
16 International Multicenter  Herrero R, Castellsagué X, Pawlita M, Lissowska J, Kee F, Balaram P, Rajkumar T, Sridhar H, Rose B, Pintos J, Fernández L, Idris A, Sánchez MJ, Nieto A, Talamini R, Tavani A, Bosch FX, Reidel U, Snijders PJ, Meijer CJ, Viscidi R, Muñoz N, Franceschi S; IARC Multicenter Oral Cancer Study Group. Human papillomavirus and the risk of Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. J Natl Cancer Inst.2003;95:1772-83.     
17 Boston / FFQ / Phase 2  Peters ES, McClean MD, Liu M, et al. The ADH1C polymorphism modifies the risk of squamous cell carcinoma of the head and neck associated with alcohol and tobacco use. Cancer Epidemiol Biomarkers Prev.2005;14:476-82.    Christensen BC, Avissar-Whiting M, Ouellet LG, Butler RA, Nelson HH, McClean MD, Marsit CJ, Kelsey KT. Mature microRNA sequence polymorphism in MIR196A2 is associated with risk and prognosis of head and neck cancer. Clin Cancer Res. 2010 Jul 15;16(14):3713-20. 
18 Rome (Boccia) old qz / new qz  Gallì P, Cadoni G, Volante M, De Feo E, Amore R, Giorgio A, Arzani D, Paludetti G, Ricciardi G, Boccia S. A case-control study on the combined effects of p53 and p73 polymorphisms on head and neck cancer risk in an Italian population. BMC Cancer. 2009 May 8;9:137.     
19 US Multicenter  Blot WJ, McLaughlin JK, Winn DM, et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res.1988; 48:3282.     
20 Sao Paulo  Boing AF, Ferreira Antunes JL, de Carvalho MB, de Góis Filho JF, Kowalski LP, Michaluart P Jr; Head and Neck Genome Project/GENCAPO, Eluf-Neto J, Boffetta P, Wünsch-Filho V. How much do smoking and alcohol consumption explain socioeconomic inequalities in head and neck cancer risk? J Epidemiol Community Health. 2010; 65:709-14.     
21 MSKCC  Schantz SP, Zhang ZF, Spitz MS, Sun M, Hsu TC. Genetic susceptibility to head and neck cancer: interaction between nutrition and mutagen sensitivity. Laryngoscope.1997;107:765-81.     
22 Seattle-Leo / FFQ / Dental  Rogers MA, Thomas DB, Davis S, Vaughan TL, Nevissi AE. A case-control study of element levels and cancer of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev. 1993 Jul-Aug;2(4):305-12.     
23 Western Europe  Lagiou P, Georgila C, Minaki P, Ahrens W, Pohlabeln H, Benhamou S, Bouchardy C, Slamova A, Schejbalova M, Merletti F, Richiardi L, Kjaerheim K, Agudo A, Castellsague X, Macfarlane TV, Macfarlane GJ, Talamini R, Barzan L, Canova C, Simonato L, Lowry R, Conway DI, McKinney PA, Znaor A, McCartan BE, Healy C, Nelis M, Metspalu A, Marron M, Hashibe M, Brennan PJ. Alcohol-related cancers and genetic susceptibility in Europe: the ARCAGE project: study samples and data collection. Eur J Cancer Prev.2009;18:76-84.     
24 Germany-Saarland (Brenner) case / control / med1 / med2 / med3  Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H. The diagnosis of a smoking-related disease is a prominent trigger for smoking cessation in a retrospective cohort study. J Clin Epidemiol. 2006 Jan;59(1):82-9.     
25 Germany-Heidelberg (Ramroth)  Dietz A, Ramroth H, Urban T, Ahrens W, Becher H. Exposure to cement dust, related occupational groups and laryngeal cancer risk: results of a population based case-control study. Int J Cancer.2004 ;108:907-11.     
27 North Carolina (2002-2006)  Divaris K, Olshan AF, Smith J, Bell ME, Weissler MC, Funkhouser WK, Bradshaw PT. Oral health and risk for head and neck squamous cell carcinoma: the Carolina Head and Neck Cancer Study. Cancer Causes Control. 2010 Apr;21(4):567-75.  Variable list for the follow-up study   
28 France Multicenter (Luce: 1989-1991, men only)  Menvielle G, Luce D, Goldberg P, Leclerc A. Smoking, alcohol drinking, occupational exposures and social inequalities in hypopharyngeal and laryngeal cancer. Int J Epidemiol. 2004; 33 (4): 799-806.     
29 HOTSPOT  Publication in progress Follow-up questionnaire   
31 Buffalo  Jayaprakash V, Rigual NR, Moysich KB et al. Chemoprevention of Head and Neck Cancer With Aspirin. Arch Otolaryngol Head Neck Surg. 2006; 132(11):1231-6.     
32 France Multicenter (Luce/Stucker; 2001-2007)  Luce D, Stücker I; ICARE Study Group. Investigation of occupational and environmental causes of respiratory cancers (ICARE): a multicenter, population-based case-control study in France. BMC Public Health. 2011 Dec 14;11:928.     
33 Baltimore (Gillison)  D'souza G, Kreimer AR, Viscidi R et al. Case-control study of human papilloma virus and oropharyngeal cancer. N Engl J Med. 2007; 10;356(19):1944-56.     
34 Beijing (Zheng)  Zheng TZ, Boyle P, Hu HF et al. Dentition, oral hygiene, and risk of oral cancer: a case-control study in Beijing, People's Republic of China. Cancer causes control. 1990; 1(3):235-41.     
35 Milan (2006-2009) (La Vecchia)  Bravi F., Bosetti C., Filomeno M., Levi F., Garavello W., Galimberti S., Negri E., La Vecchia C. Foods, nutrients and the risk of oral and pharyngeal cancer. British Journal of Cancer (2013) 109, 2904??910.     
36 East Asia Multicenter  Lee YA, Li S, Chen Y, Li Q, Chen CJ, Hsu WL, Lou PJ, Zhu C, Pan J, Shen H, Ma H, Cai L, He B, Wang Y, Zhou X, Ji Q, Zhou B, Wu W, Ma J, Boffetta P, Zhang ZF, Dai M, Hashibe M. Tobacco smoking, alcohol drinking, betel quid chewing, and the risk of head and neck cancer in an East Asian population. Head Neck. 2019 Jan;41(1):92-102.     
104 Michigan (Follow-up only)   Follow-up questionnaire  Arthur AE, Peterson KE, Rozek LS, Taylor JM, Light E, Chepeha DB, Hébert JR, Terrell JE, Wolf GT, Duffy SA; UM Head and Neck SPORE Program. Pretreatment dietary patterns, weight status, and head and neck squamous cell carcinoma prognosis. Am J Clin Nutr. 2013 Feb;97(2):360-8. 
105 Toronto (Follow-up only)   Baseline questionnaire; follow-up questionnaire  Habbous S, Chu KP, Qiu X, La Delfa A, Harland LT, Fadhel E, Hui A, Perez-Ordonez B, Weinreb I, Liu FF, Waldron J, O'Sullivan B, Goldstein D, Xu W, Huang SH, Liu G. The changing incidence of human papillomavirus-associated oropharyngeal cancer using multiple imputation from 2000 to 2010 at a Comprehensive Cancer Centre. Cancer Epidemiol. 2013 Dec;37(6):820-9. 
106 UK5000   Follow-up questionnaire  Ingarfield, K, McMahon, AD, Hurley, K, et al. Inequality in survival of people with head and neck cancer: Head and Neck 5000 cohort study. Head and Neck. 2021; 1– 19. 
107 Sao Paulo 2 (Follow-up only)     GENCAPO 1 questionnaire (2005-2010, portuguese); GENCAPO 2 questionnaire (2010-2015)   
    Studies NOT in the central pooled data:
Northeast (SNP only) 
India (SNP only) 
Pittsburgh (GWAS follow up only) 
Netherlands(SNP only) 

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