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(last updated April 21, 2023)


Meetings & telephone conferences

1st meeting in Orlando, FL (March 30, 2004):
Agenda and Participants / Minutes

2nd meeting in Seattle, WA (February 10-11, 2005):
Agenda / Participants / Minutes / Slides ( 6 slides/page or 2 slides/page) / Group picture

3rd meeting in Bethesda, MD (January 19, 2006)
Agenda / Participants / Minutes / Slides / Handouts / Group picture

4th meeting at IARC, Lyon, France (January 18-19, 2007)
Agenda / Participants / Minutes / Slides ( 6 slides or 2 slides) / Handouts / Authorship guideline draft / Group picture

5th meeting at MD Anderson Cancer Center, Houston, Texas (February 20, 2008)
Agenda and Participants / Minutes / Slides (15MB) / Group picture

6th meeting at INSERM, Paris, France (March 24-25, 2009)
Agenda and Participants / Minutes / Slides (5MB) / Group picture

7th Annual INHANCE Meeting at NCI, Bethesda, MD, USA (April 21-22, 2010)
Agenda / Participants / Minutes / Slides (2MB) / Group picture

8th Annual INHANCE Meeting at Mount Sinai School of Medicine, New York City (March 22, 2011)
Agenda / Participants / Minutes / Slides (4MB) / Group picture

9th Annual INHANCE Meeting at Mario Negri, Milan, Italy (May 2, 2012)
Agenda / Participants / Minutes / Slides (9MB) / Group picture

10th Annual INHANCE Meeting at Mount Sinai, New York, NY USA (May 8, 2013)
Agenda / Participants / Minutes / Slides (7.5MB) / Group picture

11th Annual INHANCE Meeting at Universita Cattolica Del Sacro Cuore, Rome, Italy (June 4, 2014)
Agenda / Participants / Minutes / Slides (7.2MB) / Group picture

12th Annual INHANCE Meeting at Mount Sinai New York Eye and Ear Infirmary, New York, NY, USA (May 29, 2015)
Agenda / Participants / Minutes / Slides (4.39MB) / Group picture

13th Annual INHANCE Meeting at Curie Institute, Paris, France (June 3, 2016)
Agenda / Participants / Minutes / Slides (9.02MB) / Group picture

14th Annual INHANCE Meeting at Mount Sinai, New York City, USA (May 26, 2017)
Agenda / Participants / Minutes (updated on July 5, 2017!) / Slides (10MB) / Group picture / Group dinner picture

15th Annual INHANCE Meeting at University of Milan, Milan, Italy (June 29, 2018)
Agenda / Participants / Minutes / Slides (18MB) / Group picture / Group dinner picture

16th Annual INHANCE Meeting at Mt. Sinai, New York City, USA (April 12, 2019)
Agenda / Participants / Minutes / Slides (4MB) / Group picture / Group dinner picture

2020 Annual INHANCE Meeting on zoom (November 18, 2020)
Agenda / Participants / Minutes / Slides  / Group picture

2021 Annual INHANCE Meeting on zoom (May 11, 2021)
Agenda / Participants / Minutes / Slides  / Group picture

2022 Annual INHANCE Meeting on zoom (September 16, 2022)
Agenda / Participants / Minutes / Slides  / Group picture

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Executive Committee

Telephone conference minutes
July 2006 / December 2006 / April 2007 / July 2007 / July 2008 / October 2008 / May 2010 / October 2010 / February 2011 / April 2011 / February 2012
April 2012/ June 2012/ October 2012/ March 2013/ November 2013 / March 2014/ March 2016/ December 2016/ March 2018/ October 2018/ January 2019
November 2021

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Other documents

INHANCE Consortium Guidelines

INHANCE Publication Guidelines

Head & Neck Cancer Classification Criteria (Wei)

ICD-O-2 Classification (Boffetta)

Analysis proposal form  (updated on Nov. 2021)

INHANCE data dictionary, v1.6

Pooling methods, v1.6

INHANCE follow-up data dictionary (updated on Oct. 2021)

Pooling methods for follow-up studies  (updated on Oct. 2021)

INHANCE application form 2012

References for INHANCE studies (in Reference Manager format - .zip)

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  • Please download the excel file with tables for study summary, study design, questionnaire information, and biological samples
Questionnaires and representative publications from consortium studies
Study no Questionnaire Publication Questionnaire for follow-up studies Publication for follow-up studies
1 Milan (1984-1989) Franceschi S, Talamini R, Barra S, et al. Smoking and drinking in relation to cancers of the oral cavity, pharynx, larynx, and esophagus in northern Italy. Cancer Res.1990;50:6502-7    
2 Aviano Negri E, La Vecchia C, Franceschi S, Tavani A. Attributable risk for oral cancer in northern Italy. Cancer Epidemiol Biomarkers Prev.1993;2:189-93.    
3 France (1987-1992) Benhamou S, Tuimala J, Bouchardy C, Dayer P, Sarasin A, Hirvonen A. DNA repair gene XRCC2 and XRCC3 polymorphisms and susceptibility to cancers of the upper aerodigestive tract. Int J Cancer. 2004 Dec 10;112(5):901-4.    
4 Italy Multicenter Bosetti C, Gallus, S, Trichopoulou A, Talamini R, Franceschi S, Negri E, et al. Influence of the Meditterranean diet on the risk of cancers of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev.2003; 12: 1091-4.    
5 Switzerland Levi F, Pasche C, La Vecchia C, et al. Food groups and risk of oral and pharyngeal cancer. Int J Cancer 1998;77:705-9.    
6 Central Europe Hashibe M, Boffetta P, Zaridze D, Shangina O, Szeszenia-Dabrowska N, Mates D, Janout V, Fabiánová E, Bencko V, Moullan N, Chabrier A, Hung R, Hall J, Canzian F, Brennan P. Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev. 2006;15:696-703.    
7 NY Multicenter (AHF) Muscat JE, Richie JP Jr., Thompson S, Wynder EL. Gender differences in smoking and risk for oral cancer. Cancer Res.1996;56:5192-97.    
8 Seattle (1985-1995) Rosenblatt KA, Daling JR, Chen C, Sherman KJ, Schwartz SM. Marijuana use and risk of oral squamous cell carcinoma. Cancer Res.2004;64:4049-54.    
9 Iowa Smith EM, Hoffman HT, Summersgill KS, Kirchner HL, Turek LP, Haugen TH. Human papillomavirus and risk of oral cancer. Laryngoscope.1998;108:1098???¡V103.    
10 North Carolina (1994-1997) Olshan AF, Weissler MC, Watson MA, Bell DA. GSTM1, GSTT1, GSTP1, CYP1A1, and NAT1 polymorphisms, tobacco use, and the risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev.2000;9:185-91.    
11 Tampa Elahi A, Zheng Z, Park J, Eyring K, McCaffrey T, Lazarus P. The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk. Carcinogenesis.2002;23:1229-34.    
12 Los Angeles Cui Y, Morgenstern H, Greenland S, et al. Polymorphism of xeroderma pigmentosum group G and the risk of lung cancer and squamous cell carcinomas of the oropharynx, larynx and esophagus. Int J Cancer.2006;118:714-20.    
13 Houston Zhang Z, Shi Q, Liu Z, Sturgis EM, Spitz MR, Wei Q. Polymorphisms of methionine synthase and methionine synthase reductase and risk of squamous cell carcinoma of the head and neck: a case-control analysis. Cancer Epidemiol Biomarkers Prev.2005;14:1188-93.    
14 Puerto Rico Hayes RB, Bravo-Otero E, Kleinman DV, et al. Tobacco and alcohol use and oral cancer in Puerto Rico. Cancer Causes Control.1999;10:27-33.    
15 Latin America Szymańska K, Hung RJ, Wünsch-Filho V, Eluf-Neto J, Curado MP, Koifman S, Matos E, Menezes A, Fernandez L, Daudt AW, Boffetta P, Brennan P. Alcohol and tobacco, and the risk of cancers of the upper aerodigestive tract in Latin America: a case-control study. Cancer Causes Control.2011;22:1037-46.    
16 International Multicenter Herrero R, Castellsagué X, Pawlita M, Lissowska J, Kee F, Balaram P, Rajkumar T, Sridhar H, Rose B, Pintos J, Fernández L, Idris A, Sánchez MJ, Nieto A, Talamini R, Tavani A, Bosch FX, Reidel U, Snijders PJ, Meijer CJ, Viscidi R, Muñoz N, Franceschi S; IARC Multicenter Oral Cancer Study Group. Human papillomavirus and the risk of Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. J Natl Cancer Inst.2003;95:1772-83.    
17 Boston / FFQ / Phase 2 Peters ES, McClean MD, Liu M, et al. The ADH1C polymorphism modifies the risk of squamous cell carcinoma of the head and neck associated with alcohol and tobacco use. Cancer Epidemiol Biomarkers Prev.2005;14:476-82.   Christensen BC, Avissar-Whiting M, Ouellet LG, Butler RA, Nelson HH, McClean MD, Marsit CJ, Kelsey KT. Mature microRNA sequence polymorphism in MIR196A2 is associated with risk and prognosis of head and neck cancer. Clin Cancer Res. 2010 Jul 15;16(14):3713-20.
18 Rome (Boccia) old qz / new qz Gallì P, Cadoni G, Volante M, De Feo E, Amore R, Giorgio A, Arzani D, Paludetti G, Ricciardi G, Boccia S. A case-control study on the combined effects of p53 and p73 polymorphisms on head and neck cancer risk in an Italian population. BMC Cancer. 2009 May 8;9:137.    
19 US Multicenter Blot WJ, McLaughlin JK, Winn DM, et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res.1988; 48:3282.    
20 Sao Paulo Boing AF, Ferreira Antunes JL, de Carvalho MB, de Góis Filho JF, Kowalski LP, Michaluart P Jr; Head and Neck Genome Project/GENCAPO, Eluf-Neto J, Boffetta P, Wünsch-Filho V. How much do smoking and alcohol consumption explain socioeconomic inequalities in head and neck cancer risk? J Epidemiol Community Health. 2010; 65:709-14.    
21 MSKCC Schantz SP, Zhang ZF, Spitz MS, Sun M, Hsu TC. Genetic susceptibility to head and neck cancer: interaction between nutrition and mutagen sensitivity. Laryngoscope.1997;107:765-81.    
22 Seattle-Leo / FFQ / Dental Rogers MA, Thomas DB, Davis S, Vaughan TL, Nevissi AE. A case-control study of element levels and cancer of the upper aerodigestive tract. Cancer Epidemiol Biomarkers Prev. 1993 Jul-Aug;2(4):305-12.    
23 Western Europe Lagiou P, Georgila C, Minaki P, Ahrens W, Pohlabeln H, Benhamou S, Bouchardy C, Slamova A, Schejbalova M, Merletti F, Richiardi L, Kjaerheim K, Agudo A, Castellsague X, Macfarlane TV, Macfarlane GJ, Talamini R, Barzan L, Canova C, Simonato L, Lowry R, Conway DI, McKinney PA, Znaor A, McCartan BE, Healy C, Nelis M, Metspalu A, Marron M, Hashibe M, Brennan PJ. Alcohol-related cancers and genetic susceptibility in Europe: the ARCAGE project: study samples and data collection. Eur J Cancer Prev.2009;18:76-84.    
24 Germany-Saarland (Brenner) case / control / med1 / med2 / med3 Twardella D, Loew M, Rothenbacher D, Stegmaier C, Ziegler H, Brenner H. The diagnosis of a smoking-related disease is a prominent trigger for smoking cessation in a retrospective cohort study. J Clin Epidemiol. 2006 Jan;59(1):82-9.    
25 Germany-Heidelberg (Ramroth) Dietz A, Ramroth H, Urban T, Ahrens W, Becher H. Exposure to cement dust, related occupational groups and laryngeal cancer risk: results of a population based case-control study. Int J Cancer.2004 ;108:907-11.    
27 North Carolina (2002-2006) Divaris K, Olshan AF, Smith J, Bell ME, Weissler MC, Funkhouser WK, Bradshaw PT. Oral health and risk for head and neck squamous cell carcinoma: the Carolina Head and Neck Cancer Study. Cancer Causes Control. 2010 Apr;21(4):567-75. Variable list for the follow-up study  
28 France Multicenter (Luce: 1989-1991, men only) Menvielle G, Luce D, Goldberg P, Leclerc A. Smoking, alcohol drinking, occupational exposures and social inequalities in hypopharyngeal and laryngeal cancer. Int J Epidemiol. 2004; 33 (4): 799-806.    
29 HOTSPOT Publication in progress Follow-up questionnaire  
31 Buffalo Jayaprakash V, Rigual NR, Moysich KB et al. Chemoprevention of Head and Neck Cancer With Aspirin. Arch Otolaryngol Head Neck Surg. 2006; 132(11):1231-6.    
32 France Multicenter (Luce/Stucker; 2001-2007) Luce D, Stücker I; ICARE Study Group. Investigation of occupational and environmental causes of respiratory cancers (ICARE): a multicenter, population-based case-control study in France. BMC Public Health. 2011 Dec 14;11:928.    
33 Baltimore (Gillison) D'souza G, Kreimer AR, Viscidi R et al. Case-control study of human papilloma virus and oropharyngeal cancer. N Engl J Med. 2007; 10;356(19):1944-56.    
34 Beijing (Zheng) Zheng TZ, Boyle P, Hu HF et al. Dentition, oral hygiene, and risk of oral cancer: a case-control study in Beijing, People's Republic of China. Cancer causes control. 1990; 1(3):235-41.    
35 Milan (2006-2009) (La Vecchia) Bravi F., Bosetti C., Filomeno M., Levi F., Garavello W., Galimberti S., Negri E., La Vecchia C. Foods, nutrients and the risk of oral and pharyngeal cancer. British Journal of Cancer (2013) 109, 2904??910.    
36 East Asia Multicenter Lee YA, Li S, Chen Y, Li Q, Chen CJ, Hsu WL, Lou PJ, Zhu C, Pan J, Shen H, Ma H, Cai L, He B, Wang Y, Zhou X, Ji Q, Zhou B, Wu W, Ma J, Boffetta P, Zhang ZF, Dai M, Hashibe M. Tobacco smoking, alcohol drinking, betel quid chewing, and the risk of head and neck cancer in an East Asian population. Head Neck. 2019 Jan;41(1):92-102.    
104 Michigan (Follow-up only)   Follow-up questionnaire Arthur AE, Peterson KE, Rozek LS, Taylor JM, Light E, Chepeha DB, Hébert JR, Terrell JE, Wolf GT, Duffy SA; UM Head and Neck SPORE Program. Pretreatment dietary patterns, weight status, and head and neck squamous cell carcinoma prognosis. Am J Clin Nutr. 2013 Feb;97(2):360-8.
105 Toronto (Follow-up only)   Baseline questionnaire; follow-up questionnaire Habbous S, Chu KP, Qiu X, La Delfa A, Harland LT, Fadhel E, Hui A, Perez-Ordonez B, Weinreb I, Liu FF, Waldron J, O'Sullivan B, Goldstein D, Xu W, Huang SH, Liu G. The changing incidence of human papillomavirus-associated oropharyngeal cancer using multiple imputation from 2000 to 2010 at a Comprehensive Cancer Centre. Cancer Epidemiol. 2013 Dec;37(6):820-9.
106 UK5000   Follow-up questionnaire Ingarfield, K, McMahon, AD, Hurley, K, et al. Inequality in survival of people with head and neck cancer: Head and Neck 5000 cohort study. Head and Neck. 2021; 1– 19.
107 Sao Paulo 2 (Follow-up only


GENCAPO 1 questionnaire (2005-2010, portuguese); GENCAPO 2 questionnaire (2010-2015)




Studies NOT in the central pooled data:
Northeast (SNP only)
India (SNP only)
Pittsburgh (GWAS follow up only)
Netherlands(SNP only)

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