Spine
Mission
Our mission is to advance the understanding, diagnosis, and treatment of spinal disorders through innovative and interdisciplinary research. We are committed to improving patient outcomes by integrating cutting-edge biomedical science, clinical expertise, and evidence-based medicine.
Through collaboration, education, and discovery, we strive to lead transformative research that enhances spine health across the lifespan and informs spine care providers on a national and global scale.
Our research mission allows patients unparalleled access to clinical trials and cutting-edge treatments for both traumatic, degenerative, and oncologic conditions of the spine.
The University Orthopaedic Spine Service includes: Dr. Brodke, Dr. Lawrence, Dr. Spiker, Dr. Spina and Dr. Karamian
Leading the way
Our research team is at the forefront of advancing spinal care through comprehensive, high-impact research across the full spectrum of spinal pathology. Our multidisciplinary team of surgeons, scientists, and clinical researchers is committed to improving patient outcomes by driving innovation in diagnosis, treatment, and recovery.
Degenerative Spine Disease
We investigate the biological and biomechanical mechanisms underlying degenerative spine conditions such as disc herniation, spinal stenosis, and spondylolisthesis. Our team is pioneering novel surgical techniques, implant technologies, and value-based care strategies to enhance function and reduce disability in aging and active populations alike.
Spinal Infections
Our research in spinal infections focuses on improving early detection, optimizing antimicrobial therapies, and refining surgical interventions for complex cases such as vertebral osteomyelitis and spinal hardware infections. We collaborate closely with infectious disease specialists to guide evidence-based protocols and reduce complication rates.
Spine Oncology
Our spine tumor research encompasses both primary and metastatic disease. Our studies explore tumor biology, surgical innovation, radiation synergy, and quality-of-life outcomes to help shape the future of care for patients with spinal cancer.
Spine Trauma
Our trauma research aims to improve the management of spinal fractures, spinal cord injuries, and polytrauma. We lead efforts in surgical stabilization, neuroprotective strategies, and long-term functional recovery, often in collaboration with trauma surgery, and rehabilitation medicine.
Spine Epidemiology
We apply population-based and health services research methods to better understand the burden, disparities, and outcomes associated with spinal disorders. Our epidemiologic work helps inform policy, optimize care pathways, and identify risk factors that shape both individual outcomes and system-level performance.
Spine Implants and Technology
Our team is advancing the design, testing, and implementation of next-generation spinal implants and surgical technologies. We study implant biomechanics, material science, motion preservation, and image-guided navigation. Through industry partnerships and in-house innovation, we are redefining safety, precision, and long-term outcomes in spinal instrumentation.
Innovation and Impact
Across all domains, our research team is committed to data-driven care, personalized medicine, and surgical excellence. Our work is supported by NIH funding, foundation grants, industry partnerships, and active engagement in multicenter trials. Through rigorous investigation and training of future clinician-scientists, we continue to lead the way in advancing spine surgery research at both national and international levels.