Researchers at the University of Utah School of Medicine and ARUP Laboratories in Salt Lake City unravel the mystery behind a rare Zika-related death in an adult, and unconventional transmission to a second patient in a correspondence published online on September 28 in the New England Journal of Medicine. Details point to an unusually high concentration of virus in the first patient’s blood as being responsible for his death. The phenomenon may also explain how the second patient may have contracted the virus through casual contact with the primary patient, the first such documented case. ... Read MorePathology
Department of Pathology
The Department of Pathology is dedicated to understanding the basis of disease, to teach knowledge to others, and to apply our understanding to improve medical diagnoses and treatment of patients. The research goal in the Department of Pathology is to extend our knowledge of the mechanisms of disease, especially at the molecular level. Such detailed information will hopefully lead to improved diagnoses, treatment, and eventually, prevention.
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By age 56, Roma Jean Ockler had endured 17 years of recurring infections and a life-threatening intestinal illness before finally receiving the right treatment for her condition. Her family’s genetic information was combined with that of five other families from across the world to classify a new immune disorder. The finding makes possible diagnosis at a young age so that doctors can intervene early and give the right treatment from the start.... Read MorePathology
A study led by the University of Utah School of Medicine has identified molecular mechanisms that control an immune cell’s ability to remember. They found that in helper T cells, the proteins Oct1 and OCA-B work together to put immune response genes on standby so that they are easily activated when the body is re-exposed to a pathogen. The research, which could inform strategies for developing better vaccines, was performed in collaboration with scientists from The Broad Institute and University of Michigan, and published in The Journal of Experimental Medicine.... Read MorePathology
U pathologist who served on committee says doctor-patient communication is a critical part of the solution.... Read MorePathology
VA study with U and Utah State University researchers looked at vets returning from Afghanistan and Iraq conflicts... Read MorePathology