Antibiotics were the wonder drug of the 20th century, but many bacteria have evolved resistance. According to the CDC, more than two million people in the United States develop bacterial infections that are resistant to multiple antibiotics every year.... Read MorePathology
Department of Pathology
The Department of Pathology is dedicated to understanding the basis of disease, to teach knowledge to others, and to apply our understanding to improve medical diagnoses and treatment of patients. The research goal in the Department of Pathology is to extend our knowledge of the mechanisms of disease, especially at the molecular level. Such detailed information will hopefully lead to improved diagnoses, treatment, and eventually, prevention.
The Department of Pathology is happy to welcome Brian Evavold, PhD. Dr. Evavold has recently arrived in Utah, and will serve as Professor in the M&I Division.... Read MorePathology
The studies have broad implications for understanding how different lineages of a developing embryo are specified, and thus are relevant to the field of regenerative medicine, in which using this information specific cell types and organ systems could be better engineered. The work involved investigators in the University of Utah Department of Pathology and Broad Institute of Harvard and MIT. The work was funded by the National Institutes of Health.... Read MorePathology
During the past decade, the gut has experienced a renaissance as investigations focus on the role of the microbiome on human health. While most studies have focused on bacteria, the dominant microbial inhabitants in the gut, scientists at University of Utah Health Sciences used mouse studies to show the role of yeast in aggravating the symptoms of Inflammatory Bowel Disease (IBD). Their work suggests that allopurinol, a generic drug already on the market, could offer some relief. ... Read MorePathology
Researchers at the University of Utah School of Medicine and ARUP Laboratories in Salt Lake City unravel the mystery behind a rare Zika-related death in an adult, and unconventional transmission to a second patient in a correspondence published online on September 28 in the New England Journal of Medicine. Details point to an unusually high concentration of virus in the first patient’s blood as being responsible for his death. The phenomenon may also explain how the second patient may have contracted the virus through casual contact with the primary patient, the first such documented case. ... Read MorePathology
By age 56, Roma Jean Ockler had endured 17 years of recurring infections and a life-threatening intestinal illness before finally receiving the right treatment for her condition. Her family’s genetic information was combined with that of five other families from across the world to classify a new immune disorder. The finding makes possible diagnosis at a young age so that doctors can intervene early and give the right treatment from the start.... Read MorePathology