Department of Pathology

The Department of Pathology is dedicated to understanding the basis of disease, to teach knowledge to others, and to apply our understanding to improve medical diagnoses and treatment of patients. The research goal in the Department of Pathology is to extend our knowledge of the mechanisms of disease, especially at the molecular level. Such detailed information will hopefully lead to improved diagnoses, treatment, and eventually, prevention.

Latest News

Case Study Reports Details of Mysterious Utah Zika-Related Death
Research
Sep 28, 2016

Case Study Reports Details of Mysterious Utah Zika-Related Death

Internal Medicine, , zika, infectious disease

Researchers at the University of Utah School of Medicine and ARUP Laboratories in Salt Lake City unravel the mystery behind a rare Zika-related death in an adult, and unconventional transmission to a second patient in a correspondence published online on September 28 in the New England Journal of Medicine. Details point to an unusually high concentration of virus in the first patient’s blood as being responsible for his death. The phenomenon may also explain how the second patient may have contracted the virus through casual contact with the primary patient, the first such documented case. ... Read More

Pathology
Within Six Families, a Path to Personalized Treatment for an Immune Disorder
Research
Mar 16, 2016

Within Six Families, a Path to Personalized Treatment for an Immune Disorder

Internal Medicine, , immunology, precision medicine, genetics

By age 56, Roma Jean Ockler had endured 17 years of recurring infections and a life-threatening intestinal illness before finally receiving the right treatment for her condition. Her family’s genetic information was combined with that of five other families from across the world to classify a new immune disorder. The finding makes possible diagnosis at a young age so that doctors can intervene early and give the right treatment from the start.... Read More

Pathology
Research
Oct 20, 2015

Building Immune System Memory

immune system, vaccine

A study led by the University of Utah School of Medicine has identified molecular mechanisms that control an immune cell’s ability to remember. They found that in helper T cells, the proteins Oct1 and OCA-B work together to put immune response genes on standby so that they are easily activated when the body is re-exposed to a pathogen. The research, which could inform strategies for developing better vaccines, was performed in collaboration with scientists from The Broad Institute and University of Michigan, and published in The Journal of Experimental Medicine.... Read More

Pathology

Welcome from our Chair

Peter Jensen

Peter E. Jensen, MD
ARUP Presidential Professor and Chair

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