Publications

Genomic/transcriptomics of cerebrovascular disease

A map of transcriptional heterogeneity and regulatory variation in human microglia.

Young AMH, Kumasaka N, Calvert F, Hammond TR, Knights A, Panousis N, Park JS, Schwartzentruber J, Liu J, Kundu K, Segel M, Murphy NA, McMurran CE, Bulstrode H, Correia J, Budohoski KP, Joannides A, Guilfoyle MR, Trivedi R, Kirollos R, Morris R, Garnett MR, Timofeev I, Jalloh I, Holland K, Mannion R, Mair R, Watts C, Price SJ, Kirkpatrick PJ, Santarius T, Mountjoy E, Ghoussaini M, Soranzo N, Bayraktar OA, Stevens B, Hutchinson PJ, Franklin RJM, Gaffney DJ.

Nat Genet. 2021 Jun;53(6):861-868.

The pathophysiology and treatment of delayed cerebral ischaemia following subarachnoid haemorrhage.

Budohoski KP, Guilfoyle M, Helmy A, Huuskonen T, Czosnyka M, Kirollos R, Menon DK, Pickard JD, Kirkpatrick PJ.

J Neurol Neurosurg Psychiatry. 2014 Dec;85(12):1343-53.

Pharmacologic Management of Subarachnoid Hemorrhage.

Young AM, Karri SK, Helmy A, Budohoski KP, Kirollos RW, Bulters DO, Kirkpatrick PJ, Ogilvy CS, Trivedi RA.

World Neurosurg. 2015 Jul;84(1):28-35. 

Systemic, local, and imaging biomarkers of brain injury: more needed, and better use of those already established?

Carpenter KL, Czosnyka M, Jalloh I, Newcombe VF, Helmy A, Shannon RJ, Budohoski KP, Kolias AG, Kirkpatrick PJ, Carpenter TA, Menon DK, Hutchinson PJ.

Front Neurol. 2015 Feb 18;6:26. 

Elevated Baseline C-Reactive Protein as a Predictor of Outcome After Aneurysmal Subarachnoid Hemorrhage: Data From the Simvastatin in Aneurysmal Subarachnoid Hemorrhage (STASH) Trial. Neurosurgery.

Turner CL, Budohoski K, Smith C, Hutchinson PJ, Kirkpatrick PJ, Murray GD; STASH collaborators.

Multimodal monitoring

Impairment of cerebral autoregulation predicts delayed cerebral ischemia after subarachnoid hemorrhage: a prospective observational study.

Budohoski KP, Czosnyka M, Smielewski P, Kasprowicz M, Helmy A, Bulters D, Pickard JD, Kirkpatrick PJ.

Stroke. 2012 Dec;43(12):3230-7. 

Cerebral autoregulation after subarachnoid hemorrhage: comparison of three methods. J Cereb Blood Flow Metab.

Budohoski KP, Czosnyka M, Smielewski P, Varsos GV, Kasprowicz M, Brady KM, Pickard JD, Kirkpatrick PJ. 

"Optimal cerebral perfusion pressure" in poor grade patients after subarachnoid hemorrhage.

Bijlenga P, Czosnyka M, Budohoski KP, Soehle M, Pickard JD, Kirkpatrick PJ, Smielewski P.

Neurocrit Care. 2010 Aug;13(1):17-23. 

Cerebral compromise and multimodality monitoring after SAH.

Budohoski KP, Czosnyka M, Kirkpatrick PJ.

Neurosurgery. 2012 Mar;70(3):E801-2. 

Bilateral failure of cerebral autoregulation is related to unfavorable outcome after subarachnoid hemorrhage.

Budohoski KP, Czosnyka M, Kirkpatrick PJ, Reinhard M, Varsos GV, Kasprowicz M, Ząbek M, Pickard JD, Smielewski P.

Neurocrit Care. 2015 Feb;22(1):65-73. 

Cerebral vasospasm affects arterial critical closing pressure.

Varsos GV, Budohoski KP, Czosnyka M, Kolias AG, Nasr N, Donnelly J, Liu X, Kim DJ, Hutchinson PJ, Kirkpatrick PJ, Varsos VG, Smielewski P. J

Cereb Blood Flow Metab. 2015 Feb;35(2):285-91. 

Growing Evidence: Dysautoregulation May Trigger Ischemic Deficit After Subarachnoid Hemorrhage.

Budohoski KP, Czosnyka M.

Crit Care Med. 2018 May;46(5):828-829. 

Baroreflex Impairment After Subarachnoid Hemorrhage Is Associated With Unfavorable Outcome.

Nasr N, Gaio R, Czosnyka M, Budohoski K, Liu X, Donnelly J, Sykora M, Kirkpatrick P, Pavy-Le Traon A, Haubrich C, Larrue V, Smielewski P.

Stroke. 2018 Jul;49(7):1632-1638. 

Clinical relevance of cerebral autoregulation following subarachnoid haemorrhage.

Budohoski KP, Czosnyka M, Kirkpatrick PJ, Smielewski P, Steiner LA, Pickard JD.

Nat Rev Neurol. 2013 Mar;9(3):152-63.

Twenty-Five Years of Intracranial Pressure Monitoring After Severe Traumatic Brain Injury: A Retrospective, Single-Center Analysis.

Donnelly J, Czosnyka M, Adams H, Cardim D, Kolias AG, Zeiler FA, Lavinio A, Aries M, Robba C, Smielewski P, Hutchinson PJA, Menon DK, Pickard JD, Budohoski KP.

Neurosurgery. 2019 Jul 1;85(1):E75-E82.

Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury.

Aries MJ, Czosnyka M, Budohoski KP, Steiner LA, Lavinio A, Kolias AG, Hutchinson PJ, Brady KM, Menon DK, Pickard JD, Smielewski P.

Crit Care Med. 2012 Aug;40(8):2456-63. 

The limitations of near-infrared spectroscopy to assess cerebrovascular reactivity: the role of slow frequency oscillations.

Diedler J, Zweifel C, Budohoski KP, Kasprowicz M, Sorrentino E, Haubrich C, Brady KM, Czosnyka M, Pickard JD, Smielewski P.

Anesth Analg. 2011 Oct;113(4):849-57. 

Global health

Defining the minimal requirements for implementing stroke thrombectomy programs in low resource settings
Provider Survey

Casemix, management, and mortality of patients rreseceiving emergency neurosurgery for traumatic brain injury in the Global Neurotrauma Outcomes Study: a prospective observational cohort study.

Clark D, Joannides A, Adeleye AO, Bajamal AH, Bashford T, Biluts H, Budohoski K, Ercole A, Fernández-Méndez R, Figaji A, Gupta DK, Härtl R, Iaccarino C, Khan T, Laeke T, Rubiano A, Shabani HK, Sichizya K, Tewari M, Tirsit A, Thu M, Tripathi M, Trivedi R, Devi BI, Servadei F, Menon D, Kolias A, Hutchinson P; Global Neurotrauma Outcomes Study collaborative.

Lancet Neurol. 2022 May;21(5):438-449. 

Neurosurgical Randomized Trials in Low- and Middle-Income Countries.

Griswold DP, Khan AA, Chao TE, Clark DJ, Budohoski K, Devi BI, Azad TD, Grant GA, Trivedi RA, Rubiano AM, Johnson WD, Park KB, Broekman M, Servadei F, Hutchinson PJ, Kolias AG.

Neurosurgery. 2020 Sep 1;87(3):476-483. 

Neurosurgery in East Africa: Foundations.

Mangat HS, Schöller K, Budohoski KP, Ngerageza JG, Qureshi M, Santos MM, Shabani HK, Zubkov MR, Härtl R, Stieg PE.

World Neurosurg. 2018 May;113:411-424. 

The Growth of Neurosurgery in East Africa: Challenges.

Santos MM, Qureshi MM, Budohoski KP, Mangat HS, Ngerageza JG, Schöller K, Shabani HK, Zubkov MR, Härtl R.

World Neurosurg. 2018 May;113:425-435.

Neurosurgery in East Africa: Innovations.

Budohoski KP, Ngerageza JG, Austard B, Fuller A, Galler R, Haglund M, Lett R, Lieberman IH, Mangat HS, March K, Olouch-Olunya D, Piquer J, Qureshi M, Santos MM, Schöller K, Shabani HK, Trivedi RA, Young P, Zubkov MR, Härtl R, Stieg PE.

World Neurosurg. 2018 May;113:436-452. 

View all of Dr. Budohoski's publications in the NIH PubMed Database