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CT Surgery Research Highlights | Winter Newsletter

RECENT PUBLICATIONS

SAMPLES OF RECENT PUBLICATIONS

Adult Cardiac

Antonoff, M. B., Donington, J., Husain, S. A., Kaneko, T., Kilic, A., & Pereira, S. J. (2025). STS Policy for Respectful Scholarly Discourse: Providing a Framework for Professional Behavior at Academic Conferences. The Annals of thoracic surgery119(2), 268–273. https://doi.org/10.1016/j.athoracsur.2024.09.051

Taleb, I., Giannouchos, T. V., Kyriakopoulos, C. P., Clawson, A., Davis, E. S., Sideris, K., Tseliou, E., Shah, K. S., Tonna, J. E., Dranow, E., Jones, T. L., Carter, S. J., Fang, J. C., Stehlik, J., Ohsfeldt, R. L., Selzman, C. H., Hanff, T. C., & Drakos, S. G. (2024). Cost-Effectiveness of a Shock Team Approach in Refractory Cardiogenic Shock. Circulation. Heart failure17(11), e011709. https://doi.org/10.1161/CIRCHEARTFAILURE.124.011709

Sideris, K., Zhang, M., Wohlfahrt, P., Siu, A. F., Shen, J., Carter, S., Kyriakopoulos, C. P., Taleb, I., Wever-Pinzon, O., Shah, K., Selzman, C. H., Rodriguez-Correa, C., Kapelios, C., Brinker, L., Alharethi, R., Hess, R., Drakos, S. G., Steinberg, B. A., Fang, J. C., Kfoury, A. G., … Stehlik, J. (2024). Integration of Patient Reported Quality-of-life Data into Risk Assessment in Heart Failure. Journal of cardiac failure, S1071-9164(24)00381-6. Advance online publication. https://doi.org/10.1016/j.cardfail.2024.08.053

Owyang, C. G., Rippon, B., Teran, F., Brodie, D., Araos, J., Burkhoff, D., Kim, J., & Tonna, J. E. (2024). Pulmonary Artery Pressures and Mortality During Venoarterial ECMO: An ELSO Registry Analysis. Circulation. Heart failure17(7), e011123. https://doi.org/10.1161/CIRCHEARTFAILURE.123.011123

Pediatric

Griffiths, E. R., Profsky, M. P., Mokshagundam, D., Boucek, K., Amdani, S., Davies, R. R., Monge, M. C., Morales, D. L., Rossano, J. W., Jacobs, J. P., Kirklin, J. K., Koehl, D., Cantor, R., Peng, D. M., & Pedimacs Investigators (2025). Eighth Annual Society of Thoracic Surgeons Pedimacs Report. The Annals of thoracic surgery, S0003-4975(25)00009-8. Advance online publication. https://doi.org/10.1016/j.athoracsur.2024.12.020

Vossler, J. D., Eckhauser, A. W., Griffiths, E. R., Hobbs, R. D., Lambert, L. M., Tani, L. Y., Parsons, N., Habib, R. H., Jacobs, J. P., Jacobs, M. L., & Husain, S. A. (2024). Impact of Atrioventricular Valve Intervention at Each Stage of Single Ventricle Palliation. World journal for pediatric & congenital heart surgery15(6), 724–730. https://doi.org/10.1177/21501351241269924

Marrone, T. N., Amula, V., Niu, M. C., Ou, Z., & Griffiths, E. R. (2024). ECG Abnormalities, Diastolic Blood Pressure, and Adverse Events After Systemic to Pulmonary Artery Shunt in Infants with Congenital Heart Disease. Pediatric cardiology, 10.1007/s00246-024-03645-z. Advance online publication. https://doi.org/10.1007/s00246-024-03645-z

Thoracic

Brown, L. M., Bonnell, L., Parsons, N., Cooke, D. T., Godoy, L. A., David, E. A., Schipper, P., Varghese, T. K., Jr, Habib, R., & Mitzman, B. (2025). Predictors of Discharge With Supplemental Oxygen After Lobectomy for Lung Cancer. The Annals of thoracic surgery119(1), 180–189. https://doi.org/10.1016/j.athoracsur.2024.08.009

Kent, M. S., Mitzman, B., Diaz-Gutierrez, I., Khullar, O. V., Fernando, H. C., Backhus, L., Brunelli, A., Cassivi, S. D., Cerfolio, R. J., Crabtree, T. D., Kakuturu, J., Martin, L. W., Raymond, D. P., Schumacher, L., & Hayanga, J. W. A. (2024). The Society of Thoracic Surgeons Expert Consensus Document on the Management of Pleural Drains After Pulmonary Lobectomy: Expert Consensus Document. The Annals of thoracic surgery118(4), 764–777. https://doi.org/10.1016/j.athoracsur.2024.04.016

Mitzman B. (2024). The Entire NSCLC Spectrum: No Cancer Left Behind. The Annals of thoracic surgery118(2), 393–394. https://doi.org/10.1016/j.athoracsur.2024.02.002

Translational

Corbin, A., Aromolaran, K. A., & Aromolaran, A. S. (2025). Leukotriene B4 is elevated in diabetes and promotes ventricular arrhythmogenesis in guinea pig. Journal of cellular physiology240(1), e31467. https://doi.org/10.1002/jcp.31467

Bahrami, P., Aromolaran, K. A., & Aromolaran, A. S. (2024). Mechanistic Relevance of Ventricular Arrhythmias in Heart Failure with Preserved Ejection Fraction. International journal of molecular sciences25(24), 13423. https://doi.org/10.3390/ijms252413423

Li, J., Balmaceda, P., Ha, T., Visker, J. R., Maalouf, N., Kwan, E., Hoareau, G. L., Accad, M., Ranjan, R., Selzman, C. H., Drakos, S. G., Shaw, R. M., & Hong, T. (2024). Cardiac bridging integrator 1 gene therapy rescues chronic non-ischemic heart failure in minipigs. NPJ Regenerative medicine9(1), 36. https://doi.org/10.1038/s41536-024-00380-0

A full list of our research publications from the past couple of years can be found here

SUBMITTED FUNDING

Thoracic

  • Brian Mitzman, MD MSCI FACS FCCP
    • Title(s): K08; AHRQ
    • Sponsor: DHHS Agency for Healthcare Research & Quality 

AWARDED FUNDING

Aromolara Ademuyiwa, PhD

  • Title(s): R01 PA 20-185 Targeting IL-6; Role for Leukorienes
  • Sponsor: DHHS National Institutes of Health 

Craig Selzman, MD

  • Title: Randomized Controlled Trail Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery (CRYPTICS)
  • Sponsor: Department of Defense (DoD) 

STUDY HIGHLIGHT

PI: Craig Selzman, MD 

Project: Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure (INNOVATE) Trial

Sponsor:  BrioHealth Solutions, Inc. The University of Utah is participating as a study site with Dr. Selzman as the site lead PI.

Background: Left Ventricular Assist Devices (LVADs) work to help the heart pump blood when it cannot. This is typically used when an individual is in advanced heart failure. There is a new LVAD device and it is unclear how or if it works as well as or better than the current LVAD devices used in standard of care. The purpose of this study is to evaluate the safety and efficacy of the BrioVAD system when used for treatment for advanced, refractory, LVHF when compared with the HeartMate 3 device.  

Study Design: Participants are eligible if they are at least 18 years of age, in advanced HF (NYHA Class III or IV), and approval for LVAD implant. If enrolled, they will be followed for 2 years. Participants will be randomized to either BrioVAD System or HeartMate 3 Device in a 1:1 randomization. 

For more information: 

DID YOU KNOW?

CT Surgery Research encompasses: 

  • Adult Cardiac
  • Pediatric Cardiac (Primary Children’s)
  • Huntsman team (Huntsman Cancer Institute)
  • Animal Lab Research
  • Perfusion 

Don’t see your publication or research highlight? Want to share new updates or projects in the works? Please contact Margaret (Margaret.carlson@hsc.utah.edu) to reflect in the next newsletter.