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Clinical Trials in Movement Disorders

The Movement Disorders Division at the University of Utah is currently involved in a total of fourteen clinical research studies (six of them are in Parkinson’s disease). Below is a brief synopsis of some of these studies.

Lab Research Trial

Actively Recruiting Trials

"Cardiovascular Autonomic Regulation & Exercise in Parkinson's Disease (CARE-PD)"

A study to determine the effect of an acute bout of moderate aerobic exercise on post-exercise cardiovascular function in PD.

Principal Investigator: Erin Suttman

Site Principal Investigator: Erin Suttman

If interested contact erin.suttman@utah.edu.   

"Enroll-HD: A Prospective Registry Study in a Global Huntington Disease (HD) Cohort" | Cure Huntington’s Disease Initiative Foundation (CHDI)

A worldwide, longitudinal research study of Huntington’s Disease (HD). Clinical information and biological samples are collected at annual visits to try and find new treatments for the disease. Our site is actively enrolling participants with Huntington’s disease as well as their families. 

Site Principal Investigator: Paolo Moretti

For more information, please contact Clinical Research Coordinator Kendra Fowler: (801) 581-7828; Kendra.Fowler@utah.edu.

"Study in Parkinson Disease of Exercise Phase 3 Clinical Trial (SPARX3)" | National Institutes of Health

A study to learn more about the effects of aerobic exercise on people with Parkinson’s disease who have been diagnosed in the last three years and have not started taking medications for their PD symptoms.

Primary Investigator: Daniel Corcos

Coinvestigator: Paolo Moretti

You can visit the SPARX3 webpage for more information about the study. To be screened for enrollment, please call (801) 587-3181 or email G.Olivier@utah.edu.

"Physiologic Correlates of Vocal Tremor Affecting Those with Essential Tremor" | National Institutes of Health

Essential tremor is one of the most common movement disorders in the world. Approximately 30% of these individuals exhibit a vocal tremor, with the majority being female. This study will evaluate mechanisms of vocal tremor and their effects on communication, with the goal of advancing current and future treatments. 

Principal Investigator: Julie Barkmeier-Kraemer

Coinvestigator: Paolo Moretti

For more information, please contact Clinical Research Coordinator Derrik Legler at Derrik.Legler@hsc.utah.edu. 

Next-Generation Clinical Phenotyping and Pathophysiology of Laryngeal Dystonia and Voice Tremor

The University of Utah is a participating research site on this P50 grant awarded by the NIH/NIDCD. The study creates specialized centers and cross-disciplinary research focused on understanding the clinical and pathophysiologic features of laryngeal dystonia (i.e. spasmodic dysphonia) and voice tremor.

Principal Investigator: Kristina Simonyan

Coinvestigators: Paolo Moretti (U of Utah; Movement Disorders) and J. Rolston and S. Rahinpour (U of Utah; Functional Neurosurgery)

For more information, please contact Jessica.Ku@hsc.utah.edu. 

Effect of Levodopa on Cardiovascular Autonomic Function in Parkinson’s Disease with and without Orthostatic Hypotension: A Cross-Over Study

Levodopa is the most common medication used to treat the symptoms of Parkinson’s disease. Research is needed for us to better understand how Levodopa affects the blood pressure and heart rate in patients with Parkinson’s disease. 

For more information, please contact Guillaume.Lamotte@hsc.utah.edu.

For additional information about these studies, please contact paola.wall@hsc.utah.edu or kendra.fowler@hsc.utah.edu.

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