Research Overview
The research of Behrad Noudoost, MD, PhD, and his lab is focused precisely on understanding the neural circuits and biological mechanisms that are necessary and sufficient to drive fundamental cognitive functions.
Selective attention and working memory play a profound role in many of the tasks of everyday life; like driving a car, reading, and holding a conversation in a crowded room. These cognitive abilities are an integral part of all our goal-oriented interactions with the world around us. The ultimate goal of the lab’s research is an understanding of the neural basis of selective attention and working memory.
In particular, the lab is studying the role of prefrontal control of visual cortical signals in these cognitive processes. This work involves electrophysiological recording, electrical stimulation, and pharmacological manipulation of neural activity in animals trained to perform tasks involving covert attention, spatial, and object working memory.
Research Interests
- Cognitive neuroscience
- Prefrontal Modulation of the Visual Cortex
NIH Funding FY25
- Sensory Recruitment by Working Memory: Neuronal Basis and Neural Circuitry
- Prefrontal Contributions to Phase-Dependent Representation of Visual Information
Research Publications
- Working memory expedites the processing of visual signals within the extrastriate cortex. Roshanaei M, Bahmani Z, Clark K, Daliri MR, Noudoost B. iScience. 2024 Jul 11;27(8):110489.
- Neural correlates of perisaccadic visual mislocalization in extrastriate cortex. Weng G, Akbarian A, Clark K, Noudoost B, Nategh N. Nat Commun. 2024 Jul 27;15(1):6335.
- Information representation in an oscillating neural field model modulated by working memory signals. Nesse WH, Clark KL, Noudoost B. Front Comput Neurosci. 2024 Jan 18;17:1253234.
- Neural correlates of perisaccadic visual mislocalization in extrastriate cortex. Weng G, Akbarian A, Clark K, Noudoost B, Nategh N. bioRxiv [Preprint]. 2023 Nov 7:2023.11.06.565871.
- A Recruitment Through Coherence Theory of Working Memory. Comeaux P, Clark K, Noudoost B. Prog Neurobiol. 2023 Sep;228:102491.
- Dependence of Working Memory on Coordinated Activity Across Brain Areas. Rezayat E, Clark K, Dehaqani MA, Noudoost B. Front Syst Neurosci. 2022 Jan 13;15:787316
- A Sensory Memory to Preserve Visual Representations Across Eye Movements. Akbarian A, Clark K, Noudoost B, Nategh N. Nat Commun. 2021 Nov 8;12(1):6449.