Study Type: Qualitative, Observational
Current Status: Active
Utah Principal Investigator: Cali Johnson, MD, EdD
Brief Summary: This is a qualitative study that examines the needs and family wellbeing of patients and their caregivers before and after undergoing vascular surgery.
ClinicalTrials.gov Identifier: NCT01658787
Study type: Observational (Patient Registry)
Current Status: Active, Not Recruiting
Utah Principal Investigator: Benjamin Brooke, MD, PhD
Brief Summary: This is a prospective observational cohort registry designed to obtain data on device performance and clinical outcomes of patients treated with Gore Endovascular Aortic products.
ClinicalTrials.gov Identifier: NCT06087029
Study Type: Interventional
Current Status: Recruiting
Utah Principal Investigator: Benjamin Brooke, MD, PhD
Brief Summary: This study is for patients with an uncomplicated Type B Aortic Dissection. There are currently two types of treatment for this condition: Medical management or surgery (an operation known as a TEVAR) combined with medical management. This study seeks to understand which treatment type should be considered the standard of care for patients with this condition.
Patients will be randomized 1:1 (50:50) to one of the following groups:
- Medical Management: This will consist of a change in lifestyle and addition (or modification) of antihypertensive medications.
- Surgery (TEVAR) + Medical Management: Surgery will occur within 48 hours to 6 weeks of diagnosis. You will also be provided with the same change in lifestyle and addition (or modification) of antihypertensive medication.
ClinicalTrials.gov Identifier: NCT04370691
Study Type: Observational (Patient Registry)
Current Status: Recruiting
Utah Principal Investigator: Benjamin Brooke, MD, PhD
Brief Summary: This is a prospective registry designed to obtain data on device performance and clinical outcomes of patients treated with the JETi Peripheral Thrombectomy System for the diagnosis of acute/subacute thrombosis in the peripheral vascular system.
ClinicalTrials.gov Identifier: NCT06001918
Study Type: Interventional
Current Status: Recruiting
Utah Principal Investigator: Cali Johnson, MD, EdD
Brief Summary: This study is for patients with small to mid-sized abdominal aortic aneurysms (AAAs). No proven treatment options are currently available for small to mid-sized AAAs; it is recommended to monitor the growth in size of the AAA over time, known as surveillance or "watching and waiting." Once AAA reaches a certain size and/or symptoms change, your vascular surgeon will assess and discuss open surgical repair or the placement of a large tube (graft) inside the AAA to line the aortic vessel.
Nectero Medical is developing a novel treatment that may slow growth and potentially prevent rupture/bursting of small to mid-sized AAA. The Nectero EAST procedure is performed using sedation. A catheter, a thin, long tube-like device with inflatable balloons at the end, is introduced through a small cut in the groin. Once in the aneurysm, pentagalloyl glucose or PGG mixture, is delivered via holes in the balloon directly into the aneurysmal wall where it acts to strengthen the wall and potentially prevent further weakening. This one-time treatment is expected to have a lasting effect. The entire procedure takes ~1 hour.
If you qualify for this study, you will be randomly assigned (50:50 chance) to either:
- Receive the study treatment. The hospital staff will schedule you for the procedure within 30 days of your recent CT scan.
- Be in the non-treatment group. You will not undergo the study treatment, but will be followed for increased evaluation of your AAA.
ClinicalTrials.gov Identifier: NCT04943172
Study Type: Interventional (Clinical Trial)
Current Status: Closed to new enrollment, follow up ongoing
Utah Principal Investigator: Kaohinani Longwolf, MD
Brief Summary: For subjects with deep venous valvular insufficiency that have active ulcers, a history of ulcers or skin changes on one of their legs. We will implant the VenoValve into the major deep vein of the leg to help improve blood flow in the affected limb.
ClinicalTrials.gov Identifier: NCT04246463
Study Type: Observational (Patient Registry)
Current Status: Recruiting
Utah Principal Investigator: Cali Johnson, MD, EdD; and Jason Glotzbach, MD
Brief Summary: This is a prospective registry designed to obtain safety and performance data on the use of the Terumo Aortic RelayPro Thoracic Stent-Graft system to treat a lesion of the descending thoracic aorta.
ClinicalTrials.gov Identifier: NCT02850588
Study type: Observational (Patient Registry)
Current Status: Active, Recruiting
Utah Principal Investigators: Benjamin Brooke, MD, PhD; Larry Kraiss, MD
Brief Summary: The TCAR Surveillance Project (TSP) is an initiative of the Society for Vascular Surgery Patient Safety Organization (SVS PSO). The TSP is a surveillance registry designed to monitor the safety and effectiveness of transcarotid stents placed directly in to the carotid artery while reversing blood flow within the carotid artery to reduce stroke risk. It will compare this less-invasive surgical procedure with standard carotid endarterectomy in centers that participate in the Vascular Quality Initiative (VQI).
ClinicalTrials.gov Identifier: NCT04697784
Study Type: Interventional (Clinical Trial)
Current Status: Closed to new enrollment, follow up ongoing
Utah Principal Investigator: Cali Johnson, MD, EdD
Brief Summary: For subjects who have been diagnosed with an abdominal aortic aneurysm (AAA). This study will be used to determine the long-term performance of the TREO abdominal stent-graft when used to repair abdominal aortic aneurysms.
Study type: Qualitative, Observational
Current Status: Active
Principal Investigator: Benjamin Brooke, MD, PhD
Brief Summary: Using the Health Maintenance Application we will track the disease progress and quality of life in patients who have been diagnosed peripheral vascular disease (PVD).
