2024
Trainee Publications
- Congratulations to Ryan Andrews, a post doc with the Bass Lab, who co-authored a review with Brenda that was recently published in Molecular Cell.
- Good work to Julio Fierro, a graduate student in the Roh-Johnson Lab, who submitted a manuscript about how Dictyostelium make adhesions with the substrate during cell migration!
- Emily Parnell and lab technician, Erin Jenson with the Miller Lab had a paper accepted in Current Biology describing their discovery of a conserved binding site on kinetochores that facilitates dynamic recruitment of the kinase Mps1 to promote accurate chromosome segregation.
- A paper by first author Dr. Claudia Consalvo, who recently obtained her Ph.D. in the Bass Lab will soon be published in eLife. The paper is entitled "C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA" and includes co-authors Deji Aderounmu, Helen Donelick, Debra Eckert and Peter Shen.
- Congratulations to Amanda Mixon, a graduate student in the Sigala Lab, whose paper “Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis” was accepted for review and publication at eLife.
- Zach Wilson, a postdoc in the Hughes Lab, had two back to back papers accepted at the Journal of Cell Biology describing the structure and cargo selectivity of MDCs.
- Sophia Varady, a graduate student in the Roh-Johnson Lab, submitted a manuscript on macrophage effects on cancer cell proliferation.
- Daniel Greiner, a graduate student in the Roh-Johnson Lab, submitted a manuscript on engineering macrophages to kill cancer cells.
- The Ducker lab congratulates lab technician, Hayden Low on the publication of his first-author paper “Phospholipid isotope tracing suggests beta-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma”.
2023
Trainee Publications
- Congratulations to Tanya Espino-Sanchez from the Sigala Lab. Her paper entitled, "Sparks of Change" has been accepted for publications in eLife.
- Congratulations to members of the Shen lab, who have a manuscript accepted at Bio Protocols entitled, "Rapid Isolation of Endogenous Multi-component Complexes for Cryo-EM Imaging."
- Qian Xue’s paper on in vivo focal adhesions was accepted to the journal of cell biology. Congrats also to Sophia Varady, Trinity Waddell, Mackenzie Roman, and James Carrington for their contributions to this work.
- A new publication in Frontiers in Immunology from recent PhD graduate Judah Evangelista (Kay Lab) in collaboration with Con Yost’s lab in Pediatrics: "Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial by inhibiting neutrophil extracellular traps”
- Onyka Obidi helped the Chandrasekharan Lab in HCI with Multi angle light scattering experiments and the paper describing the structure and functional determinants of Rad6–Bre1 subunits in the histone H2B ubiquitin-conjugating complex was published in Nucleic Acids research.
- Kevin Hicks’ paper describing MIDAS was accepted for publication in Science.
- Jordan Berg’s paper on Metaboverse was accepted for publication in Nature Cell Biology.
- Congratulations to Tanya Espino, Henry Wienkers, and co-authors from the Sigala and Hill labs. Their paper entitled, "Direct Tests of Cytochrome c and c1 Functions in the Electron Transport Chain of Malaria Parasites" has been accepted for publications in PNAS.
- Bass lab graduate student Deji Aderounmu's first author paper has been accepted for publication in eLife. Joe Aruscavage of the Bass lab is also an author on this paper, titled "Ancestral protein reconstruction reveals evolutionary events governing variation in Dicer helices function"
- Congratulations to Elliott Paine, Jack Skalickly, and Doug Mackay with the Sundquist lab - their paper on the importance of the cysteine protease CALPAIN-7 for abcission and its timing, was just accepted and published in eLife.
- Congratulations to Tanya Espino-Sanchez, whose essay on her experience as a first generation PhD student was published in eLife in their "Sparks of Change" series.
- Congratulations to Megan Okada from the Sigala lab, who had an article accepted at PLoS Pathogens.
- Congratulations to Libby Mumby, from the English lab and co-authors for ‘A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ’ being accepted for publication at Nature Communications.
2022
Trainee Publications
Jake Winter published a first author paper in eLife, "Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction."
Sierra Scamfer and Mark Lee had a review published in Frontiers in Cell Development Biology, "Ciliary control of adipocyte progenitor cell fate regulates energy storage"
Yongxiang Zhao published a review entitled “Structural pharmacology of cation-chloride cotransporters”
Congratulations to members of the Shen lab, who have a manuscript accepted at Bio Protocols entitled, "Rapid Isolation of Endogenous Multi-component Complexes for Cryo-EM Imaging."
Qian Xue’s paper on in vivo focal adhesions was accepted to the journal of cell biology. Congrats also to Sophia Varady, Trinity Waddell, Mackenzie Roman, and James Carrington for their contributions to this work.
Congratulations to Sage Geher in the Sigala lab, who was co-author on a collaborative paper with Bruce Gale’s lab in Mechanical Engineering that developed a novel microfluidic application to separate red blood cells infected with malaria parasites.
A collaborative paper with the Ullman lab describing a comprehensive survey of the interactions between human MIT and ESCRT-III proteins was just published in eLife. Congratulations to Dawn Wenzel, Doug Mackay, Jack Skalicky and Elliott Paine.
Zaily Connell and Laura McCullough (Formosa Lab) published, 'The interaction between the Spt6-tSH2 domain and Rpb1 affects multiple functions of RNA Polymerase II,' in Nucleic Acids Research.
Alan Blakely is a first author on a paper accepted to Nature Chemical Biology that reports the discovery of a new class of snail venom insulins, development of a potent humanized variant of these insulins, and cryoEM structures of one of these humanized venom insulins in complex with the human insulin receptor. This work is collaborative with the labs of Helena Safavi-Hemami and Danny Chou.
Qian Xue submitted her manuscript on the regulation of focal adhesions during single cell migration in vivo. This work was in collaboration with current and former members of the lab: Sophia Varady, Trinity Waddell, and James Carrington.
Congratulations to Yongxiang Zhao, whose paper titled “Structural Basis for Inhibition of the Cation-chloride Cotransporter NKCC1 by the Diuretic Drug Bumetanide” was accepted for publication at Nature Communications.
Congratulations to Yongxiang Zhao and Qinzhe Wang, whose paper titled “Structure of the Human Cation-chloride Cotransport KCC1 in an Outward-open State” was accepted for publication at PNAS.
Daniel Greiner submitted a paper to “Current Protocols in Immunology” with Jarrod Johnson’s lab, titled: Genetic modification of primary human myeloid cells to study cell migration, activation, and organelle dynamics"
The Shen and Hill labs have a collaborative manuscript that has been accepted for publication in Nature Communications. The manuscript entitled, "Active conformation of the p97-p47 complex" describes the structure of the world's most important protein, the p97 AAA ATPase, in the act of unfolding a protein substrate. The work was led by former postdocs Yang Xu and Han Han, with support from Ian Cooney and Alina Guo.
Daniel Greiner’s manuscript was accepted to Current Protocols, in collaboration with Jarrod Johnson’s lab.
Julio Fierro and Qian Xue’s review was accepted to Frontiers in Cell and Developmental Biology.
Sarah Hansen published a first author paper in eLife reporting her Ph.D. research with Dr. Aaron Hoskins called:
"Multi-Step Recognition of Potential 5' Splice Sites by the Saccharomyces cerevisiae U1 snRNP".
Congratulations to PhD student Megan Okada, whose paper entitled "Critical Role for Isoprenoids in Apicoplast Biogenesis by Malaria Parasites" was accepted and published in eLife.