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Sharon Eccles Steele Center for Translational Medicine (SCTM)

Breaking New Ground

The Sharon Eccles Steele Center for Translational Medicine (SCTM) was founded in 2009 to effectively turn scientific discoveries into clinical diagnostic tools and therapies for patients suffering from blinding diseases.

The SCTM is primarily focused on developing treatments for age-related macular degeneration (AMD), a leading cause of vision impairment among adults age 55 and over. AMD affects more than 20 million individuals in the United States, and its prevalence is projected to double by 2050. AMD causes a gradual loss of vision that results in significantly reduced quality of life and often depression. Progression to the late stage of AMD often leads to irreversible vision loss.

With the support of committed donors, SCTM Executive Director Gregory S. Hageman, PhD, and his team have turned a series of groundbreaking discoveries into scientifically sound strategies to prevent the onset of all forms of AMD or to slow their progression.

 

From left, SCTM Executive Director Gregory S. Hageman, PhD; Sharon Eccles Steele; and Moran CEO Randall J Olson, MD.
From left, SCTM Executive Director Gregory S. Hageman, PhD; Sharon Eccles Steele; and Moran CEO Randall J Olson, MD.

Research

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Helping Patients

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Publications

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In the News

SCTM Shares its Research with the World

Moran’s SCTM team broke new ground in 2021 to turn genetic discoveries into new AMD treatment strategies.

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New Research on Genetics and AMD Progression

SCTM research links patient genetics to rates of AMD progression and vision loss.

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Research Focuses on AMD Genetic Protections

New research hones in on AMD genetic protection to advance new treatment approaches.

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New Potential Therapy for AMD Identified

HtrA1 augmentation is potential therapy for Chromosome 10-driven age-related macular degeneration.

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New Perspectives on AMD

An international collaboration of scientists is advocating for a new way of thinking about and finding treatments for AMD.

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Reading Identified as Key Measure of AMD Visual Decline

Beyond the Eye Chart: Scientists identify reading ability and speed as crucial measures of AMD visual decline.

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New Hope for AMD Treatments

Tireless efforts by the SCTM research team have translated a deeper genetic understanding into a new therapy that stands to change the outlook for AMD patients and their families.

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The Origins of the SCTM

Be Undaunted: A Look back by Gregory S. Hageman, PhD

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