Selected Publications
- Extracellular vesicles as emerging players in glaucoma: Mechanisms, biomarkers, and therapeutic targets. Namdari M, McDonnell FS. Vision Res. 2025 Jan;226:108522.
- Consensus Recommendations for Studies of Outflow Facility and Intraocular Pressure Regulation Using Ex Vivo Perfusion Approaches. Acott TS, Fautsch MP, Mao W, Ethier CR, Huang AS, Kelley MJ, Aga M, Bhattacharya SK, Borras T, Bovenkamp D, Chowdhury UR, Clark AF, Dibas MI, Du Y, Elliott MH, Faralli JA, Gong H, Herberg S, Johnstone MA, Kaufman PL, Keller KE, Kelly RA, Krizaj D, Kuehn MH, Li HL, Lieberman R, Lin SC, Liu Y, McDonnell FS, McDowell CM, McLellan GJ, Mzyk P, Nair KS, Overby DR, Peters DM, Raghunathan V, Rao PV, Roddy GW, Sharif NA, Shim MS, Sun Y, Thomson BR, Toris CB, Willoughby CE, Zhang HF, Freddo TF, Fuchshofer R, Hill KR, Karimi A, Kizhatil K, Kopcyznski CC, Liton P, Patel G, Peng M, Pattabiraman PP, Prasanna G, Reina-Torres E, Samples EG, Samples JR, Steel CL, Strohmaier CA, Subramanian P, Sugali CK, van Batenburg-Sherwood J, Wong C, Youngblood H, Zode GS, White E, Stamer WD. Invest Ophthalmol Vis Sci. 2024 Dec 2;65(14):32.
- Modeling complex age-related eye disease. Becker S, L'Ecuyer Z, Jones BW, Zouache MA, McDonnell FS, Vinberg F. Prog Retin Eye Res. 2024 May;100:101247.
- Greater Outflow Facility Increase After Targeted Trabecular Bypass in Angiographically Determined Low-low Regions. Strohmaier CA, Wanderer D, Zhang X, Agarwal D, Toomey CB, Wahlin K, Zhang HF, Stamer WD, Weinreb RN, McDonnell FS, Huang AS. Ophthalmol Glaucoma. 2023 Nov-Dec;6(6):570-579.
- Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms. McDowell CM, Kizhatil K, Elliott MH, et al. Invest Ophthalmol Vis Sci. 2022 Feb 1;63(2):12.
- Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation. Greene AG, Eivers SB, McDonnell F, et al. Exp Eye Res. 2020 Dec;201:108349.
- Shear Stress in Schlemm's Canal as a Sensor of Intraocular Pressure. McDonnell F, Perkumas KM, Ashpole NE, et al. Sci Rep. 2020 Apr 2;10(1):5804. doi: 10.1038/s41598-020-62730-4. PubMed PMID: 32242066; PubMed Central PMCID: PMC7118084.
- Pharmacological regulation of outflow resistance distal to Schlemm's canal. McDonnell F, Dismuke WM, Overby DR, Stamer WD. Am J Physiol Cell Physiol. 2018 Jul 1;315(1):C44-C51.
- Consensus recommendations for trabecular meshwork cell isolation, characterization and culture. Keller KE, Bhattacharya SK, Borrás T, Brunner TM, et al. Exp Eye Res. 2018 Jun;171:164-173.
- Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells. Liu B, Kilpatrick JI, Lukasz B,et al. Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814.
- Increased Global DNA Methylation and Decreased TGFβ1 Promoter Methylation in Glaucomatous Lamina Cribrosa Cells. McDonnell FS, McNally SA, Clark AF, et al. J Glaucoma. 2016 Oct;25(10):e834-e842.
- Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells. McDonnell F, Irnaten M, Clark AF, et al. PLoS One. 2016;11(4):e0153354.
- The role of epigenetics in the fibrotic processes associated with glaucoma. McDonnell F, O'Brien C, Wallace D. J Ophthalmol. 2014;2014:750459.