Selected Publications
- Modeling complex age-related eye disease. Becker S, L'Ecuyer Z, Jones BW, Zouache MA, McDonnell FS, Vinberg F. Prog Retin Eye Res. 2024 May;100:101247.
- Greater Outflow Facility Increase After Targeted Trabecular Bypass in Angiographically Determined Low-low Regions. Strohmaier CA, Wanderer D, Zhang X, Agarwal D, Toomey CB, Wahlin K, Zhang HF, Stamer WD, Weinreb RN, McDonnell FS, Huang AS. Ophthalmol Glaucoma. 2023 Nov-Dec;6(6):570-579.
- Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms. McDowell CM, Kizhatil K, Elliott MH, et al. Invest Ophthalmol Vis Sci. 2022 Feb 1;63(2):12.
- Differential Lysyl oxidase like 1 expression in pseudoexfoliation glaucoma is orchestrated via DNA methylation. Greene AG, Eivers SB, McDonnell F, et al. Exp Eye Res. 2020 Dec;201:108349.
- Shear Stress in Schlemm's Canal as a Sensor of Intraocular Pressure. McDonnell F, Perkumas KM, Ashpole NE, et al. Sci Rep. 2020 Apr 2;10(1):5804. doi: 10.1038/s41598-020-62730-4. PubMed PMID: 32242066; PubMed Central PMCID: PMC7118084.
- Pharmacological regulation of outflow resistance distal to Schlemm's canal. McDonnell F, Dismuke WM, Overby DR, Stamer WD. Am J Physiol Cell Physiol. 2018 Jul 1;315(1):C44-C51.
- Consensus recommendations for trabecular meshwork cell isolation, characterization and culture. Keller KE, Bhattacharya SK, Borrás T, Brunner TM, et al. Exp Eye Res. 2018 Jun;171:164-173.
- Increased Substrate Stiffness Elicits a Myofibroblastic Phenotype in Human Lamina Cribrosa Cells. Liu B, Kilpatrick JI, Lukasz B,et al. Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):803-814.
- Increased Global DNA Methylation and Decreased TGFβ1 Promoter Methylation in Glaucomatous Lamina Cribrosa Cells. McDonnell FS, McNally SA, Clark AF, et al. J Glaucoma. 2016 Oct;25(10):e834-e842.
- Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFβ1 Expression in Human Trabecular Meshwork Cells. McDonnell F, Irnaten M, Clark AF, et al. PLoS One. 2016;11(4):e0153354.
- The role of epigenetics in the fibrotic processes associated with glaucoma. McDonnell F, O'Brien C, Wallace D. J Ophthalmol. 2014;2014:750459.