The Division of Microbiology and Immunology (M&I) at the University of Utah was established in 2011, evolving from the Division of Experimental Pathology that was founded in the 1970s. As a core unit within the Department of Pathology, the Division of M&I is comprised of internationally recognized research laboratories dedicated to advancing fundamental and translational knowledge in the biomedical sciences. Research in the Division encompasses broad and interdisciplinary areas, including host–microbe interactions, autoimmunity, tumor immunology, immunometabolism, neuroinflammation, immunotherapies, vaccine development, immunoinformatics, and more. The Division also plays a central role in the academic mission of the University of Utah by directing the M&I Graduate Program, which confers a PhD degree, and by providing a rigorous and supportive training environment for postdoctoral scholars. Through these efforts, the Division is committed to educating and mentoring the next generation of scientific leaders. Under the leadership of Division Head Ryan O’Connell, PhD, the Division of M&I fosters a collegial, professional, and highly collaborative culture that underpins its success in research, training, and service to the broader scientific and medical communities.