Publications

2017

Lin, J, Sondekamp, J, Cunningham, D, Deroost, K, Tshitenge,T, McLaughlin, S, Lamb, T, Spencer-Dean, B, Hosking, C, Ramesar, J, Janse, C, Graham, C, O’Garra, A and Langhorne, J. (2017) Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria. Scientific Reports, 7: 41722 PMID: 28155887

 

2016

Joyner C, Moreno A, Meyer EV, Cabrera-Mora M; MaHPIC Consortium, Kissinger JC, Barnwell JW, Galinski MR. (2016). Plasmodium cynomolgi infections in rhesus macaques display clinical and parasitological features pertinent to modelling vivax malaria pathology and relapse infections. Malaria Journal 15(1):451  PMID: 27590312

Hudson, LE, McDermott, CD, Stewart, TP, Hudson, WH, Fasken, MB, Corbett, AH and Lamb, TJ. (2016). Characterization of the Probiotic Yeast Saccharomyces boulardii in the Healthy Mucosal Immune System. PLoS One 11(4) e0153351 PMID: 27064465

Hudson, LE, Stewart, TP, Fasken, M, Corbett, AH and Lamb, TJ. (2016) Transformation of Probiotic Yeast and their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice. J Vis Exp 108 PMID: 26890281

 

2015

Mimche, PN, Brady, LM, Bray, CF, Hudson, LE, Fenne DW, Keeton, S, Lamb, TJ. (2015). Expression of the receptor tyrosine kinase EphB2 on dendritic cells is modulated by Toll-like receptor ligation but is not required for T cell activation. PLoS One 10(9): e0138835   PMID: 26407069

Matar CM, Anthony N, Jacobs N, Priyamvada L, Engwerda C, Speck, SH* and Lamb TJ*(2015). Gammaherpes virus co-infection impairs the generation of anti-malaria immunity turning a non-lethal malaria infection into a lethal one. PLOS pathogens 11(5):e1004858 PMID:25996913 *co-corresponding authors

Mimche, PN, Brady, LM, Bray, CF, Thapa, M, McDermott, CD, King, TP, Quicke, K, Lee, CM, Mimche, SM, Grakoui, A, Morgan, ET and Lamb TJ (2015) The receptor tyrosine kinase EphB2 contributes to liver fibrosis during mouse malaria infection. Hepatology 62(3): pp900-14 PMID: 25784101

 

2014

Hudson, LE, Fasken, MB, McDermott, CD, Kuiper, EG, Guiliano, DB, Corbett, AH and Lamb, TJ (2014). Functional heterologous protein expression by genetically engineered probiotic yeast Saccharomyces boulardii. PLOS One 9 (11): e112660 PMID: 25391025

2013

Abanyie FA, McCracken C, Kirwan P, Molloy SF, Asaolu SO, Holland CV, Gutman J and Lamb TJ (2013). Ascaris co-infection does not alter malaria-induced anaemia in a cohort of Nigerian preschool children. Malaria Journal 12(1): e1. PMID: 23282136

 

2012

Freitas do Rosario, AP, Lamb, TJ, Spence, P, Stephens, R, Lang, A, Roers, A, Muller, W, O’Garra, A and Langhorne, J (2012). IL-27 promotes IL-10 production by effector Th1 CD4+ T cells; a critical mechanism for protection from severe immunopathology during malaria infection. Journal of Immunology, 188 (3), pp1178-90 PMID: 22205023

 

2010

Fairlie-Clarke, KJ, Lamb, TJ, Langhorne, J, Graham, AL and Allen, JE (2010). Antibody isotype analysis of malaria-nematode co-infection: problems and solutions associated with cross-reactivity. BMC Immunology 11, p6 PMID: 20163714

 

2009

Saunders, A, Lamb, TJ, Pascall, J, Hutchings, A, Dion, C, Carter, C, Hepburn, L, Miller, JR, Langhorne, J and Butcher, GW (2009). No impact of malaria infection or immunisation on the expression of the immune GTPase GIMAP1 at the protein or mRNA levels. Malaria Journal, 8, p53. PMID: 19338674

 

2008

Cadman, ET, Sponaas, AM, Voisine, CV, Lamb, TJ, Ndung’u, F, Jarra, W, Harrison, V and Langhorne, J  (2008). Alterations of splenic microarchitecture in malaria are induced independently of Toll-like receptors 2, 4, 9 or MyD88, and may affect antibody affinity. Infection and Immunity, 76 (9), pp3924-3931. PMID: 18559428

Lamb, TJ and Langhorne, J. (2008) The severity of anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently from the number of circulating parasites. Malaria Journal, 7 p68 PMID: 18439291

Fenton, A, Lamb, TJ and Graham, AL (2008). Optimality analysis of Th1 /Th2 immune responses during microparasite co-infection. Parasitology 28 pp1-13. PMID: 18442426

Lamb, TJ, Harris, A, Le Goff, L, Read, AF and Allen, JE. (2008). Litomosoides sigmodontis: vaccine-induced immune responses against Wolbachia surface protein can enhance the survival of filarial nematodes during primary infection. Experimental Parasitology 118(2) pp285-289 PMID: 17919582

 

2007

Lamb, TJ, Voisine, C, Koernig, S, Egan, CA, Harnett, W and Langhorne, J. (2007) The pathology of Plasmodium chabaudi infection is not ameliorated by the secreted filarial nematode immunomodulatory molecule, ES-62. Parasite Immunology 29 pp271-276.  PMID:17430551

 

2005

Lamb, TJ, Graham, AL, Le Goff, L and Allen, JE (2005). Co-infected C57BL/6 mice mount appropriately polarized and compartmentalized cytokine responses to Litomosoides sigmodontis and Leishmania major but disease progression is altered. Parasite Immunology 27(9) pp317-324. PMID: 16149989

Graham, AL, Taylor, MD, Le Goff, L, Lamb, TJ and Allen, JE (2005). Quantitative appraisal of murine filariasis confirms host strain differences but reveals that BALB/c females are more susceptible than males to Litomosoides sigmodontis. Microbes and Infection 7(4) pp612-618. PMID: 15820154

Graham, AL, Lamb, TJ, L, Read, AF and Allen, JE (2005). Malaria-filaria co-infection in mice makes malarial disease more severe unless filarial infection achieves patency. Journal of Infectious Diseases 191(3) pp410-421 PMID:15633101

 

2004

*Lamb, TJ, Le Goff, L, Kurniawan, A, Read, AF, Guiliano, DB, Fenn, K, Blaxter, M and Allen, JE (2004). The larval stage contributes to the majority of the response against Wolbachia surface protein in filarial nematode infection. Journal of Infectious Diseases 189(1) pp120-127 PMID: 14702162  *Paper recommended to the Faculty of 1000

 

2002

Le Goff, L, Lamb TJ, Graham, AL, Harcus, Y and Allen, JE. (2002). IL4 is required to prevent filarial nematode development in resistant but not susceptible strains of mice. International Journal for Parasitology 32(10) pp1277-1282 PMID: 12204227

 

2001

Djikeng A, Ferreira L, D'Angelo M, Dolezal P, Lamb T, Murta S, Triggs V, Ulbert S, Villarino A, Renzi S, Ullu E, Tschudi C (2001) Characterisation of a candidate Trypanosoma brucei U1 snRNA gene. Molecular and Biochemical Parasitology 113 (1) pp109-115. PMID: 11254959

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