PREPARE 2 Study

PREPARE 2 Study

Study Overview

This trial aims to understand how ketamine, a medication sometimes used for pain and depression, works in women who have just had a cesarean delivery compared to others. Researchers seek to determine if ketamine behaves differently in the body after childbirth, focusing on its processing and effects. The trial includes two groups: women who have had a cesarean delivery and healthy men and women who have not recently been pregnant. Women who have recently had a cesarean delivery and are not planning to breastfeed or need ketamine for pain management might be suitable for this trial. As a Phase 1 trial, the research focuses on understanding how the treatment works in people.

Participate in the PREPARE 2 Study

Investigators

Principal Investigator: Grace Lim, MD, MSc, MBA
Co-Investigators: 

  • Amy Monroe, MPH, MBA
  • Steve Caritis, MD
  • Robert McCarthy, PharmD
  • Eydie Moses-Kolko, MD
  • Raman Venkataramanan, PhD
  • Christine Warrick, MD
  • Marcela Smid, MD
  • Rana Jawish, MD

Contact

For more information about whether you qualify to participate in this trial, please contact the study coordinator.

Natalie Bennion, MPH
PREPARE-2-study@hsc.utah.edu
(385) 209-1185

Trial Criteria

Peripartum Group

Subjects must meet all the following criteria to be eligible to enroll in the study.

  • A woman of at least 18 years of age
  • Delivering your baby via c-section at University of Utah Health
  • Delivering your baby at 37 weeks' gestational age or greater

Control Group

Subjects must meet all the following criteria to be eligible to enroll in the study.

  • At least 18 years of age
  • Have had a doctors appointment and blood tests within the past year
  • Are not currently pregnant or breastfeeding
  • Are not currently undergoing hormonal therapy