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The Co-Use of Opioid Medications and Alcohol Prevention Study (COAPS) involves revision of and participation in an existing alcohol intervention adaptation session, providing the expertise needed for clinical trials associated with the intervention. 

The opioid epidemic continues to result in serious negative consequences in the US. While some improvements have been observed for reductions in prescribing in recent years; high rates of misuse, subsequent OUD, and overdose persist. Among the most high-risk behaviors for those taking opioid medications is co-use with alcohol. The Centers for Disease Control and Prevention has stated: “…there is no safe level of alcohol use for people using opioids.” Previous research, including that of our team, shows that a significant portion of those regularly using opioid medications—particularly filling opioids at community pharmacies—are involved in the co-use of alcohol. This study proposes to leverage pharmacists’ special training in medication interactions and safety; adapt a previously developed intervention for opioid medication misuse; test its acceptability, feasibility, and preliminary efficacy; and identify barriers/facilitators to large-scale research and system-level implementation. Results will inform a subsequent powered multisite trial examining the impact of the ABI-MTM intervention on reducing the co-use of opioid medications and alcohol and improving public health nationally.


  1. Adapt and manualize an Alcohol-targeted Brief Intervention-Medication Therapy Management intervention.
  2. Test the Feasibility, Acceptability, and Preliminary Efficacy of ABI-MTM for Community Pharmacy for Patients with Concomitant Alcohol and Opioid Medication Use.
  3. Identify Pharmacy System/Practice-Level Barriers and Facilitators for Universal Alcohol Screening/Intervention among Patients with Opioid Medications.


    Principal Investigator (PI):

    • Gerald Cochran, PhD, MSW

    Multiple Principal Investigator (MPI):

    • Kenneth Hohmeier, PharmD


    • Alina Cernasev, PharmD, PhD
    • Adam J. Gordon, MD, MPH
    • Ralph Tarter, PhD
    • Craig Field, PhD

    Study Staff:

    • Project Manager: Kristi Carlston
    • Clinical Research Coordinator: Grace Broussard, SSW


    The COAPS Study is coordinated in partnership between University of Utah Health and the University of Tennessee Health Science Center.

    UT HSC Website

    UT HSC Logo


    This study is sponsored by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The mission of the NIAAA is to generate and disseminate fundamental knowledge about the adverse effects of alcohol on health and well-being, and apply that knowledge to improve diagnosis, prevention, and treatment of alcohol-related problems, including alcohol use disorder, across the lifespan.

    NIAAA Website

    NIAAA Logo


    Have Questions?

    Contact Grace Broussard at or (385) 315-0698 for more information.

    COAPS Flyer