Moderate/Severe Traumatic Brain Injury (TBI) and Accelerated Aging
This study investigates how a history of moderate-severe TBI impacts aging/health in later life.
Purpose
This study seeks to better understand the impact traumatic brain injury (TBI) has on aging and overall health later in life. Many studies have investigated the immediate impact of TBI, but our lab is expanding that to the effects less studied that occur later in life.
Methods
Our lab hopes to see how aging is impacted and how comorbidities impact life 20 years after a TBI. This will be done by obtaining neuroimaging, cognitive testing, and sweat patch biomarkers to see if there are any biomarkers related to aging and TBI.
Background
A large study including individuals with moderate to severe TBI was completed 20 years ago with cognitive testing and neuroimaging data. This study utilizes the same original test battery to better understand how a history of TBI may impact these results 20 years later. The original data will be retrospectively analyzed on their previous visit. These individuals will then be further studied as many of them keep returning for treatment of TBI comorbidities. Our goal is to include 50 out of the original 500 participants by contacting these individuals based on where they are receiving treatment.
Inclusion criteria:
Individuals (both male and female) with a moderate to severe TBI obtained at least 15 years ago, who are 40 years or older, are encouraged to participate.
Exclusion criteria:
Exclusions for participation are an inability to comply with instructions, and any contradictions for undergoing MRI (e.g., pacemaker, claustrophobia, etc.).
Resources
Click on the following links to learn more:
You can also visit the Physical Medicine and Rehabilitation lab website.
