Depression is a life-threatening medical illness with far-reaching implications.
- 16.1 million U.S. adults suffered a major depressive episode in 2015 .
- In the United States, suicide is the 10th leading cause of death overall and ranks second for the young (ages 15–34).
- 1.3 million persons attempted suicide and there were twice as many suicides (44 193) as homicides (17 193) .
- Worldwide, 300 million suffer depression and 800,000 completed suicide [3,4].
- Depression increases medical morbidity and mortality. It worsens outcomes from stroke, myocardial infarction and diabetes . Depression increases postoperative: infection, acute and chronic pain, delirium and mortality .
- Depression increases absenteeism and unemployment; decreases productivity and income. The U.S. economic burden was estimated at $210.5 billion in 2010 .
- Each year, millions of patients suffering from major depression do not receive effective therapy, and others receive relief only after many months of serial medication trials .
- The societal costs of Treatment Resistant Depression (TRD) have been estimated at $38 billion annually in the United States – 30% of the costs of all cancers combined .
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3. WHO. Depression fact sheet. 2017. Available at http://www.who.int/mediacentre/ factsheets/fs369/en/Accessed 21 March 2018.
4. WHO. Suicide fact sheet. 2018. Available at http://www.who.int/mediacentre/ factsheets/fs398/en/. Accessed 21 March 2018.
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