Swami U, Monga V, Bossler AD, Zakharia Y, Milhem M (). Durable Clinical Benefit in Patients with Advanced Cutaneous Melanoma after Discontinuation of Anti-PD-1 Therapies Due to Immune-Related Adverse Events. . Journal of Oncology.
Kessel A, McFarland TR, Sayegh N, Morton K, Sirohi D, Kohli M, Swami U, Nussenzveig R, Agarwal N, Maughan BL (). Randomized phase II trial of radium-223 (RA) plus enzalutamide (EZ) versus EZ alone in metastatic castration-refractory prostate cancer (mCRPC): Final efficacy and safety results. Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 135). [Abstract]. 39.
Barata PC, Swami U, Kessel A, Jaeger E, Wesolowski S, Chipman J, Bilen MA, Heath EI, Nandagopal L, Vaena DA, Maughan BL, Nussenzveig R, Yandell M, Kohli M, Agarwal N, Sartor OA (). Landscape of circulating tumor DNA (ctDNA) abnormalities in advanced prostate cancer (aPCa): Distinctions in African American (AA) versus Caucasian (Ca) patients. Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. J Clin Oncol 39, 2021 (suppl 6; abstr 156). [Abstract]. 39.
Barata PC, Swami U, Kessel A, Jaeger E, Wesolowski S, Chipman J, Bilen MA, Heath EI, Nandagopal L, Vaena DA, Maughan BL, Nussenzveig R, Yandell M, Kohli M, Agarwal N, Sartor OA (). Landscape of circulating tumor DNA (ctDNA) abnormalities in advanced prostate cancer (aPCa): Distinctions in African American (AA) versus Caucasian (Ca) patients. (suppl 6; abstr 156). [Abstract]. 39.
Puri, S, Kerrigan, K (). Phase Ib Study to Evaluate the Safety and Efficacy of Osimertinib in Combination with Ipilimumab in EGFR Mutated NSCLC [Abstract]. 16(3, S344), P15.02.
Kerrigan K, Sinnott J, Haaland B, Puri S, Akerley W, Patel S (). Real World Survival Outcomes of Patients with Limited Stage Small Cell Lung Cancer (LS-SCLC) by Choice of Platinum Chemotherapy. Abstract submitted for 2021 World Conference on Lung Cancer (IASLC). September 8-14, 2021 [Abstract].
Li H, Swami U, Boucher KM, Gupta S, Hawks J, Sirohi D, Agarwal N, Maughan BL (). Combination therapy with avelumab (Ave) and cabozantinib (Cabo) in patients (pts) with newly diagnosed metastatic clear cell renal cell carcinoma (mccRCC). Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. J Clin Oncol 39, 2021 (suppl 6; abstr 334). [Abstract]. 39.
Sayegh N, Swami U, Barata PC, Lilly MB, Nussenzveig R, Hensel C, Bryce AH, Bilen MA, Heath EI, Nandagopal L, Garje R, Saylor PJ, Babiker HM, Vaena DA, Kohli M, Pal SK, Sartor O, Agarwal N (). Real-world prevalence of homologous recombination repair gene (BRCA1/2 and ATM) mutations (HRRm) in patients (pts) with advanced prostate cancer (aPC) as detected by comprehensive genomic profiling (CGP) of circulating cell-free DNA (cfDNA). Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 256). [Abstract]. 39.
Rathkopf DE, Chi KN, Olmos D, Cheng HH, Agarwal N, Graff JN, Sandhu SK, Hayreh V, Lopez-Gitlitz A, Francis PSJ, Attard G (). AMPLITUDE: A study of niraparib in combination with abiraterone acetate plus prednisone (AAP) versus AAP for the treatment of patients with deleterious germline or somatic homologous recombination repair (HRR) gene-altered metastatic castration-sensitive prostate cancer (mCSPC). Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. J Clin Oncol 39, 2021 (suppl 6; abstr TPS176). [Abstract]. 39.
Reisinger R, Wesolowski S, Swami U, Barata PC, Hernandez EJ, Nussenzveig R, Lemmon G, Peterson B, Hensel C, Bilen MA, Heath EI, Nandagopal L, Saylor PJ, Babiker HM, Kohli M, Pal SK, Lilly MB, Yandell M, Sartor AO, Agarwal N (). Differences in the genomic landscape of advanced prostate cancer (aPC) patients (pts) with BRCA1 versus BRCA2 mutations as detected by machine learning analysis of the comprehensive genomic profile (CGP) of cell-free DNA (cfDNA). Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. J Clin Oncol 39, 2021 (suppl 6; abstr 162). [Abstract]. 39.
Swami U, McFarland TR, Haaland B, Kessel A, Nussenzveig R, Sayegh N, Hahn AW, Rathi N, Sirohi D, Esther J, Li H, Kohli M, Maughan BL, Goldkorn A, Agarwal N (). Association of circulating tumor cells (CTC) with survival outcomes in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in a real-world cohort. Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 59). [Abstract]. 39.
Zakharia Y, Reis R, Garje R, Swami U, Born JM, Brown JA, Nepple KG, Abuqayas B, Rajput M, Bellizzi A, Sieren JC, Rustum YM (). Phase I with expansion clinical trial of seleno-l-methionine (SLM) in combination with axitinib in patients with relapsed clear cell renal cell carcinoma (ccRCC): Bench to bedside. (suppl 6; abstr 322). [Abstract]. 39.
Barata PC, Swami U, Kessel A, Jaeger E, Wesolowski S, Chipman J, Bilen MA, Heath EI, Nandagopal L, Vaena DA, Maughan BL, Nussenzveig R, Yandell M, Kohli M, Agarwal N, Sartor OA (). Landscape of circulating tumor DNA (ctDNA) abnormalities in advanced prostate cancer (aPCa): Distinctions in African American (AA) versus Caucasian (Ca) patients. Proc Am Soc Clin Oncol, Abst 156. [Abstract].
De Bono JS, Mateo J, Fizazi K, Saad F, Shore N, Sandhu S, Chi KN, Sartor O, Agarwal N, Olmos D, Thiery-Vuillemin A, Twardowski P, Roubaud G, Ozguroglu M, Kang J, Burgents J, Gresty C, Corcoran C, Adelman CA, Hussain M (). Final overall survival (OS) analysis of PROfound: Olaparib vs physician’s choice of enzalutamide or abiraterone in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) and homologous recombination repair (HRR) gene alterations. Poster Presentation. ESMO Virtual Congress 2020, September 19-21, 2020. Annals of Oncology 31, 2020 (suppl 4; abstr 6100). [Abstract].
Loriot Y, Balar AV, Petrylak DP, Tagawa ST, Rezazadeh A, Flechon A, Jain R, Agarwal N, Bupathi M, Barthelemy P, Beuzeboc P, Palmbos PL, Kyriakopoulos CE, Pouessel D, Sternberg CN, Hong Q, Goswami T, Itri LM, Grivas P (). TROPHY-U-01 cohort 1 final results: A phase II study of sacituzamab govitecan (SG) in metastatic urothelial cancer (mUC) that has progressed after platinum (PLT) and checkpoint inhibitors (CPI). Proffered Paper. ESMO Virtual Congress 2020, September 19-21, 2020. Annals of Oncology 31, 2020 (suppl 4; abstr LBA24). [Abstract].
Eric D Johnson, MD Katerina Butler, PharmD and Sumati Gupta, MBBS (August 2021). Bone Health in Patients With Prostate Cancer: An Evidence-Based Algorithm. Federal Practitioner, (Special Issue), S20-S26.
Kerrigan, K (). Real-World Survival Outcomes of Patients with Malignant Pleural Mesothelioma by Physician’s Choice of First-line Platinum Chemotherapy. [Abstract]. 16(3 S122-123), OA09.05.
Chi KN, Chowdhury S, Bjartell A, Chung BH, de Santana Gomes AJP, Given R, Soto AJ, Merseburger AS, Ozguroglu M, Uemura H, Ye D, Triantos S, Mundle S, McCarthy SA, Larsen JS, Sun Weili, Bevans K, Zhang K, Bandyopadhyay N, Agarwal N, For the TITAN Investigators (). Final analysis results from TITAN: A phase III study of apalutamide (APA) versus placebo (PBO) in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) receiving androgen deprivation therapy (ADT). Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 11). [Abstract]. 39.
Li H, Swami U, Boucher KM, Gupta S, Hawks J, Sirohi D, Sirohi D, Agarwal N, Maughan BL (). Combination therapy with avelumab (Ave) and cabozantinib (Cabo) in patients (pts) with newly diagnosed metastatic clear cell renal cell carcinoma (mccRCC). J Clin Oncol 39, (suppl 6; abstr 334). [Abstract]. 39.
Reisinger R, Wesolowski S, Swami U, Barata PC, Hernandez EJ, Nussenzveig R, Lemmon G, Peterson B, Hensel C, Bilen MA, Heath EI, Nandagopal L, Saylor PJ, Babiker HM, Kohli M, Pal SK, Lilly MB, Yandell M, Sartor AO, Agarwal N (). Differences in the genomic landscape of advanced prostate cancer (aPC) patients (pts) with BRCA1 versus BRCA2 mutations as detected by machine learning analysis of the comprehensive genomic profile (CGP) of cell-free DNA (cfDNA). J Clin Oncol 39, (suppl 6; abstr 162). [Abstract]. 39.
Sayegh N, Swami U, Barata PC, Lilly MB, Nussenzveig R, Hensel C, Bryce AH, Bilen MA, Heath EI, Nandagopal L, Garje R, Saylor PJ, Babiker HM, Vaena DA, Kohli M, Pal SK, Sartor OA, Agarwal N (). Real-world prevalence of homologous recombination repair gene (BRCA1/2 and ATM) mutations (HRRm) in patients (pts) with advanced prostate cancer (aPC) as detected by comprehensive genomic profiling (CGP) of circulating cell-free DNA (cfDNA), (suppl 6; abstr 256). J Clin Oncol [Abstract]. 39.
Swami U, McFarland TR, Haaland B, Kessel A, Nussenzveig R, Sayegh N, Hahn AW, Rathi N, Sirohi D, Esther J, Li H, Kohli M, Maughan BL, Goldkorn A, Agarwal N (). Association of circulating tumor cells (CTC) with survival outcomes in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in a real-world cohort. Abst 59 [Abstract].
Kwan EM, Dai C, Fettke H, Hauser C, Bukczynska P, Ng N, Foroughi S, Graham LJK, Mahon KL, Tan W, Wang A, Zhao Z, Zheng T, Zhou K, Yu JJ, Du P, Horvath L, Jia S, Kohli M, Azad A (). Plasma cell-free DNA profiling of PI3K/Akt pathway aberrations in two multi-institutional independent metastatic castration-resistant prostate cancer (mCRPC) cohorts. Abst 159 [Abstract].
Reisinger R, Wesolowski S, Swami U, Barata PC, Hernandez EJ, Nussenzveig R, Lemmon G, Peterson B, Hensel C, Bilen MA, Heath EI, Nandagopal L, Saylor PJ, Babiker HM, Kohli M, Pal SK, Lilly MB, Yandell M, Sartor AO, Agarwal N (). Differences in the genomic landscape of advanced prostate cancer (aPC) patients (pts) with BRCA1 versus BRCA2 mutations as detected by machine learning analysis of the comprehensive genomic profile (CGP) of cell-free DNA (cfDNA). Proc Am Soc Clin Oncol, Abst 162. [Abstract].
McFarland TR, Nussenzveig R, Swami U, Sayegh N, Kessel A, Sharma P, Li H, Kohli M, Maughan BL, Pal SK, Agarwal N (). Comprehensive genomic profiling of matched primary prostate cancer tissue and cell-free DNA (cfDNA) to assess ontogeny of BRCA1/BRCA2 mutations. J Clin Oncol 39, (suppl 6; abstr 166). [Abstract]. 39.
Kessel A, McFarland TR, Sayegh N, Morton K, Sirohi D, Kohli M, Swami U, Nussenzveig R, Agarwal N, Maughan BL (). Randomized phase II trial of radium-223 (RA) plus enzalutamide (EZ) versus EZ alone in metastatic castration-refractory prostate cancer (mCRPC): Final efficacy and safety results. (suppl 6; abstr 135). [Abstract]. 39.
Diab A, Hamid O, Thompson J, Ros W, Eskens F, Doi T, Hu-Lieskovan S, Klempner S, Ganguly B, Fleener C, Wang X, Jo T, Liao K, Salek-Ardakani S, Taylor C, Chou J, El-Khoueiry A (). A Phase I, Open-Label, Dose-Escalation Study of the OX40 Agonist Ivuxolimab in Patients With Locally Advanced or Metastatic Cancers. Clin Cancer Res.
Kerrigan, K (). Management of Patients with EGFR and ALK-Mutated Advanced Non-Small Cell Lung Cancer Post-TKI Therapy – A Real-World Survival Analysis. [Abstract]. 16(3), 89.05.
Zengin ZB, Weipert C, Hsu J, Salgia N, Hensel C, Maughan BL, Rathi N, Goel D, Agarwal N, Choueiri TK, Pal SK (). Illustration of temporal evolution in patients with metastatic renal cell carcinoma (mRCC) using both circulating tumor DNA (ctDNA) and tissue-based genomic data. Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 347). [Abstract]. 39.
Zengin ZB, Weipert C, Hsu J, Salgia N, Hensel C, Maughan BL, Rathi N, Goel D, Agarwal N, Choueiri TK, Pal SK (). llustration of temporal evolution in patients with metastatic renal cell carcinoma (mRCC) using both circulating tumor DNA (ctDNA) and tissue-based genomic data. Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. J Clin Oncol 39, 2021 (suppl 6; abstr 347). [Abstract]. 39.
Freeman MM, Jaeger E, Zhu J, Phone A, Nussenzveig R, Caputo S, Ravindranathan D, Layton JL, Nandagopal L, Kessel A, Desai A, Koshkin VS, Basu A, Bilen MA, Swami U, Garcia JA, Agarwal A, Burgess EF, Sartor OA, Barata PC (). Multi-institutional evaluation of the clinical outcomes and genomic correlates of African Americans with metastatic castration-sensitive prostate cancer (mCSPC)(suppl 6; abstr 17). [Abstract]. 39.
Swami U, McFarland TR, Haaland B, Kessel A, Nussenzveig R, Sayegh N, Hahn AW, Rathi N, Sirohi D, Esther J, Li H, Kohli M, Maughan BL, Goldkorn A, Agarwal N (). Association of circulating tumor cells (CTC) with survival outcomes in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in a real-world cohort. (suppl 6; abstr 59). [Abstract]. 39.
McFarland TR, Nussenzveig R, Swami U, Sayegh N, Kessel A, Sharma P, Li H, Kohli M, Maughan BL, Pal SK, Agarwal N (). Comprehensive genomic profiling of matched primary prostate cancer tissue and cell-free DNA (cfDNA) to assess ontogeny of BRCA1/BRCA2 mutations. Proc Am Soc Clin Oncol, Abst 166. [Abstract].
Pal S, Tsao C, Suarez C, Kelly W, Pagliaro L, Vaishampayan UN, Loriot Y, Srinivas S, McGregor BA, Panneerselvam A, Curran D, Choueiri TK, Agarwal N (). Cabozantinib (C) in combination with atezolizumab (A) as first-line therapy for advanced clear cell renal cell carcinoma (ccRCC): Results from the COSMIC-021 study. Proffered Paper. ESMO Virtual Congress 2020, September 19-21, 2020. Annals of Oncology 31, 2020 (suppl 4; abstr 7020). [Abstract].
Grivas P, Sternberg CN, Agarwal N, Petrylak DP, Tagawa ST, Hong Q, Gladden A, Kanwal C, Goswami T, Loriot Y (). TROPHY-U-01 Cohort 3: Sacituzumab govitecan (SG) and pembrolizumab (pempbro) in patients (pts) with progression or recurrence of metastatic urothelial cancer (mUC) after platinum (PLT)-based therapy. Poster Presentation. ESMO Virtual Congress 2020, September 19-21, 2020. Annals of Oncology 31, 2020 (suppl 4; abstr 796TiP). [Abstract].
Puri S, Naqash AR, Elliot A, Oliver T, Kerrigan K, Patel S, Seeber A, Kocher F, Uperty D, Mamdani H, Kulkarni A, Lopes G, Halmos B, Borghaei H, Akerley W, Liu S, Korn WM, Owonikoko T (). Real-world multi-omic characterization of small cell lung cancer subtypes reveals differential expression of clinically relevant biomarkers. Abstract accepted for 2021 ASCO Annual Meeting. [Abstract].
Rathi N, Maughan BL, Agarwal N, Swami U (). The tango of immunotherapy and targeted therapy in metastatic renal cell carcinoma, http://tcr.amegroups.com/article/view/30099. Translational Cancer Research.
Matsubara N, De Bono JS, Olmos D, Procopio G, Kawakami S, Uran Y, van Alphen RJ, Flechon A, Carducci MA, Choi YD, Hotte SJ, Korbenfeld EP, Kramer G, Agarwal N, Dearden S, Gresty C, Kang J, Poehlein CH, Harrington E, Hussain MHA (). Olaparib efficacy in patients with metastatic castration-resistant prostate cancer (mCRPC) carrying circulating tumor (ct) DNA alterations in BRCA1, BRCA2 or ATM: Results from the PROfound study. Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 27). [Abstract]. 39.
Makrakis D, Castellano D, de Kouchkovsky I, Park JJ, Bilen MA, Agarwal N, Zakharia Y, Morales-Barrera R, Devitt ME, Nelson AA, Gatrell BA, Tripathi A, Bamias A, Rodriguez-Vida A, Liu S, McKay RR, Buznego LAA, Murgic J, Grivas P, Khaki AR (). Association between prior radical surgery (RS) and outcomes with immune checkpoint inhibitor (ICI) therapy for advanced urothelial carcinoma (aUC).Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. J Clin Oncol 39, 2021 (suppl 6; abstr 444). [Abstract]. 39.
Agarwal N, Azad A, Carles J, Chowdhury S, McGregor BA, Merseburger AS, Oudard S, Saad F, Soares A, Panneerselvam A, Wang F, Pal SK (). A phase III, randomized, open-label, study (CONTACT-02) of cabozantinib plus atezolizumab versus second novel hormone therapy (NHT) in patients (pts) with metastatic, castration-resistant prostate cancer (mCRPC). Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr TPS190). [Abstract]. 39.
Schmidt AL, Xie W, Gan CL, Wells C, Dudani S, Donskov F, Porta C, Suarez C, Szabados B, Wood L, Morales JMR, Tran B, Bjarnason GA, Yuasa T, Beuselinck B, Hansen AR, Agarwal N, Bakouny Z, Heng DYC, Choueiri TK (). The very favorable metastatic renal cell carcinoma (mRCC) risk group: Data from the International Metastatic RCC Database Consortium (IMDC). Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 339). [Abstract]. 39.
Graham J, Wells C, Dudani S, Gan CL, Donskov F, Lee JL, Kollmannsberger CK, Pal SK, Beuselinck B, Hansen AR, North SA, Bjarnason GA, Agarwal N, Kanesvaran R, Wood L, Hotte SJ, McKay RR, Choueiri TK, Hen DYC (). Effectiveness of first-line immune checkpoint inhibitors (ICI) in advanced non-clear cell renal cell carcinoma (ccRCC). 2021 Genitourinary Cancers Symposium, February 11-13, 2021. J Clin Oncol 39, 2021 (suppl 6; abstr 316). [Abstract]. 39.
Zengin ZB, Weipert C, Hsu J, Salgia N, Saam J, Choueiri TK, Agarwal N, Pal S (). Assessment of circulating cell-free tumor DNA (ctDNA) in 847 patients (pts) with metastatic renal cell carcinoma (mRCC) and concordance with tissue-based testing. Proffered Paper. ESMO Virtual Congress 2020, September 19-21, 2020. Annals of Oncology 31, 2020 (suppl 4; abstr 7010). [Abstract].
McGregor BA, Agarwal N, Suarez C, Tsao C, Kelly W, Pagliaro L, Vaishampayan UN, Castellano D, Loriot Y, Werneke S, Curran D, Choueiri TK, Pal S (). Cabozantinib (C) in combination with atezolizumab (A) in non-clear cell renal cell carcinoma (nccRCC): Results from cohort 10 of the COSMIC-021 study. Poster Presentation. ESMO Virtual Congress 2020, September 19-21, 2020. Annals of Oncology 31, 2020 (suppl 4; abstr 709P). [Abstract].
Agarwal N, Evans R, Abrams K, Dequen-OByrne P, McCrea C, Muston D, Gresty C, Ghate S, Fan L, Hettle R, Hawkins N (). Exploring the impact of treatment switching on the interim overall survival (OS) results of the PROfound study.Poster Presentation. ESMO Virtual Congress 2020, September 19-21, 2020. Annals of Oncology 31, 2020 (suppl 4; abstr 622P). [Abstract].
Kerrigan, K (). Real World Characterization of Advanced Non-Small Cell Lung Cancer in Never Smokers [Abstract]. 14(10), P1.01-35.
Kerrigan, K (). MA14.09 Real-World Survival of Relapsed Compared to De-Novo Stage IV Diagnosis of Advanced Non-Small Cell Lung Cancer [Abstract]. 14(10), S307-308.
Kerrigan, K (). Real-World Survival Outcomes of Patients with Malignant Pleural Mesothelioma by Choice of Second-line Therapy. [Abstract]. 16(3, S199), FP05.01.
McFarland TR, Nussenzveig R, Swami U, Sayegh N, Kessel A, Sharma P, Li H, Kohli M, Maughan BL, Pal SK, Agarwal N (). Comprehensive genomic profiling of matched primary prostate cancer tissue and cell-free DNA (cfDNA) to assess ontogeny of BRCA1/BRCA2 mutations. Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 166). [Abstract]. 39.
Li H, Swami U, Boucher KM, Gupta S, Hawks J, Sirohi D, Agarwal N, Maughan BL (). Combination therapy with avelumab (Ave) and cabozantinib (Cabo) in patients (pts) with newly diagnosed metastatic clear cell renal cell carcinoma (mccRCC). Poster Presentation. 2021 Genitourinary Cancers Symposium, February 11-13, 2021. J Clin Oncol 39, 2021 (suppl 6; abstr 334). [Abstract]. 39.
Freeman MM, Jaeger E, Zhu J, Phone A, Nussenzveig R, Caputo S, Ravindranathan D, Layton JL, Nandagopal L, Kessel A, Desai A, Koshkin VS, Basu A, Bilen MA, Swami U, Garcia JA, Agarwal N, Burgess EF, Sartor AO, Barata PC (). Multi-institutional evaluation of the clinical outcomes and genomic correlates of African Americans with metastatic castration-sensitive prostate cancer (mCSPC). 2021 Genitourinary Cancers Symposium, February 11-13, 2021. (suppl 6; abstr 17). [Abstract]. 39.
Kessel A, McFarland TR, Sayegh N, Morton K, Sirohi D, Kohli M, Swami U, Nussenzveig R, Agarwal N, Maughan BL (). Randomized phase II trial of radium-223 (RA) plus enzalutamide (EZ) versus EZ alone in metastatic castration-refractory prostate cancer (mCRPC): Final efficacy and safety results. Abst 135. [Abstract].
Wang X, Haaland B, Hu-Lieskovan S, Colman H, Holmen SL (2021). First line immunotherapy extends brain metastasis free survival, improves overall survival, and reduces the incidence of brain metastasis in patients with advanced melanoma. Cancer Reports.
Reisinger R, Santos VS, Nussenzveig R, Wesolowski S, Hernandez EJ, Henrie AR, Maughan BL, Swami U, Yandell M, Grivas P, Agarwal N (2021). Genomic predictors of response to PD-1 axis inhibitors in metastatic urothelial cancer (mUC) patients using machine learning analysis of tissue comprehensive genomic profiling (CGP). J Clin Oncol 39, (suppl 15; abstr 4542). [Abstract]. 39.
Swami U, McFarland TR, Haaland B, Kessel A, Nussenzveig R, Sayegh N, Hahn AW, Rathi N, Sirohi D, Esther J, Li Haoran, Kohli M, Maughan BL, Goldkorn A, Agarwal N (2021). Correlation of baseline circulating tumor cells (CTC) and associated genomic profile with survival outcomes in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in a real-world cohort. (suppl 15; abstr 5077). [Abstract]. 39.
Swami U, Hong A, El-Chaar NN, Nimke D, Ramaswamy K, Bell EJ, Sandin R, Agarwal N (2021). Real-world first-line (1L) treatment patterns in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in a U.S. health insurance database. (suppl 15; abstr 5072). [Abstract]. 39.
Barata PC, Reisinger R, Bilen MA, Heath EI, Nandagopal L, Swami U, Kessel A, Jaeger E, Wesolowski S, Chipman J, Mack A, Ravindranathan D, Maughan BL, Nussenzveig R, Yandell M, Kohli M, Lilly MB, Sartor AO, Agarwal N (2021). Differences in the tumor genomic landscape between African Americans (AA) and Caucasians (CA) advanced prostate cancer (aPC) patients (pts) by comprehensive genomic profiling (CGP) of cell-free DNA (cfDNA). (suppl 15; abstr 5058). [Abstract]. 39.
Florou V, Floudas CS, Maoz A, Naqash AR, Hildebrand G, Sokol E, Frampton GM, Puri S, Swami U, Wilky BA, Hosein PJ, Trent JC, Lopes G, Park W, Garrido-Laguna I (2021). Real-world pan-cancer landscape of frameshift mutations (FSM) and their role in predicting responses to immune checkpoint inhibitors (ICI) in patients (pts) with tumors with low tumor mutational burden (TMB). (suppl 15; abstr 2599). [Abstract]. 39.
Agarwal N, Chowdhury S, Bjartell A, Chung BH, Gomes AJPS, Given R, Juarez A, Merseburger AS, Ozguroglu M, Uemura H, Ye D, Brookman-May SD, Mundle S, McCarthy SA, Lefresne F, Dibaj S, Bevans KB, Chi KN (2021). Health-related quality of life (HRQoL) and patient-reported outcomes at final analysis of the TITAN study of apalutamide (APA) versus placebo (PBO) in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) receiving androgen deprivation therapy (ADT). [Abstract]. 39.
Makrakis D, Talukder R, Carril L, de Kouchkovsky I, Park JJ, Bilen MA, McKay RR, Agarwal N, Zakharia Y, Devitt ME, Pinato DJ, Hoimes CJ, Gartrell BA, Tripathi A, Bamias A, Drakaki A, Murgic J, Lorenzo GD, Grivas P, Khaki AR (2021). Outcomes of patients (pts) with advanced urothelial carcinoma (aUC) treated with immune checkpoint inhibitors (ICIs): Associations with age, race, sex and smoking history. [Abstract]. 39.
Barata PC, Reisinger R, Bilen MA, Heath EI, Nandagopal L, Swami U, Kessel A, Jaeger E, Wesolowski S, Chipman J, Mack A, Ravindranathan D, Maughan BL, Nussenzveig R, Yandell M, Kohli M, Lilly MB, Sartor AO, Agarwal N (2021). Differences in the tumor genomic landscape between African Americans (AA) and Caucasians (CA) advanced prostate cancer (aPC) patients (pts) by comprehensive genomic profiling (CGP) of cell-free DNA (cfDNA). [Abstract]. 39.
Duarte C, Beuselinck B, Weise N, Dizman N, Collier K, Li H, Martinez N, Elias CR, Rose TL, Brugarolas J, Agarwal N, Mortazavi A, Pal SK, McKay RR, Hu J, Lam ET (2021). Treatment outcomes in renal cell carcinoma patients with metastases to the pancreas and other sites. [Abstract]. 39.
Reisinger R, Santos VS, Nussenzveig R, Wesolowski S, Hernandez EJ, Henrie AR, Maughan BL, Swami U, Yandell M, Grivas P, Agarwal N (2021). Genomic predictors of response to PD-1 axis inhibitors in metastatic urothelial cancer (mUC) patients using machine learning analysis of tissue comprehensive genomic profiling (CGP). [Abstract]. 39.
George DJ, Agarwal N, Rider JR, Li B, Shirali R, Sandin R, Hong A, Russell D, Ramaswamy K, Freedlan SJ (2021). Real-world treatment patterns among patients diagnosed with metastatic castration-sensitive prostate cancer (mCSPC) in community oncology settings. [Abstract]. 39.
Agarwal NAzad A, Shore ND, Carles J, Fay AP, Dunshee C, Karsh LI, Paccagnella ML, Santo ND, Elmeliegy M, Lin X, Niyazov A, Czibere A, Fizazi K (2021). TALAPRO-2: A phase 3 randomized study of enzalutamide (ENZA) plus talazoparib (TALA) versus placebo in patients with new metastatic castration-resistant prostate cancer (mCRPC). [Abstract]. 39.
Agarwal N, Oudard S, Rodriguez JMMP, Schweizer MT, Flechon A, Gordoa TA, Nacerddine K, Lithio A, Johnston EL, Smith MR (2021). CYCLONE 1: A phase 2 study of abemaciclib in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with a novel hormonal agent and taxane-based chemotherapy [Abstract]. 39.
Agarwal N, Tangen C, Hussain MH, Gupta S, Plets M, Lara P, Harzstark A, Twardowski P, Paller CJ, Zylla DM, Zibelman MR, Levine EG, Roth BJ, Goldkorn RA, Vaena DA, Kohli M, Crispino T, Vogelzang NJ, Thompson IM, Quinn DI (2021). SWOG S1216:A phase III randomized trial comparing androgen deprivation therapy (ADT) plus TAK-700 with ADT plus bicalutamide in patients (pts) with newly diagnosed metastatic hormone-sensitive prostate cancer (mHSPC) (NCT01809691) [Abstract]. 39.
Swami U, McFarland TR, Haaland B, Kessel A, Nussenzveig R, Sayegh N, Hahn AW, Rathi N, Sirohi D, Esther J, Li Haoran, Kohli M, Maughan BL, Goldkorn A, Agarwal N (2021). Correlation of baseline circulating tumor cells (CTC) and associated genomic profile with survival outcomes in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in a real-world cohort. [Abstract]. 39.
Vaia Florou, Charalampos S Floudas, Asaf Maoz, Abdul Rafeh Naqash, Gregory Hildebrand, Ethan Sokol, Garrett M Frampton, Sonam Puri, Umang Swami, Breelyn A Wilky, Peter Joel Hosein, Jonathan C Trent, Gilberto Lopes, Wungki Park, Ignacio Garrido-Laguna (ASCO 2021). Real-world pan-cancer landscape of frameshift mutations (FSM) and their role in predicting responses to immune checkpoint inhibitors (ICI) in patients (pts) with tumors with low tumor mutational burden (TMB). [Abstract]. 39(2021), (suppl 15: abstr 2599).
Amanda Gammon, Ambreen Khan, Joanne M Jeter (2021). Evaluation of cohort diversity in development and validation studies of hereditary cancer genetic risk assessment models. [Abstract].
Freedland SJ, Agarwal N, Ramaswamy K, Sandin R, Russell D, Hong A, Yang H, Gao W, Hagan K, George DJ (2021). Real-world utilization of advanced therapies and racial disparity among patients with metastatic castration-sensitive prostate cancer (mCSPC): A Medicare database analysis. [Abstract]. 39.
Swami U, Hong A, El-Chaar NN, Nimke D, Ramaswamy K, Bell EJ, Sandin R, Agarwal N (2021). Real-world first-line (1L) treatment patterns in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) in a U.S. health insurance database. [Abstract]. 39.
Tannir NM, Agarwal N, Porta C, Lawrence NJ, Motzer RJ, Lee RJ, Jain RK, Davis NB, Appleman LJ, Goodman OB, Stadler WM, Gandhi SG, Geynisman DM, Mellado RIB, Figlin RA, Powles T, Akella LV, Orford KW, Escudier B (2021). CANTATA: Primary analysis of a global, randomized, placebo (Pbo)-controlled, double-blind trial of telaglenastat (CB-839) + cabozantinib versus Pbo + cabozantinib in advanced/metastatic renal cell carcinoma (mRCC) patients (pts) who progressed on immune checkpoint inhibitor (ICI) or anti-angiogenic therapies. [Abstract]. 39.
Kelley KC, Grossman KF, Brittain-Blankenship M, Thorne KM, Akerley WL, Terrazas MC, Kosak KM, Boucher KM, Buys SS, McGregor KA, Werner TL, Agarwal N, Weis JR, Sharma S, Ward JH, Kennedy TP, Sborov DW, Shami PJ (2021). A Phase 1 dose-escalation study of disulfiram and copper gluconate in patients with advanced solid tumors involving the liver using S-glutathionylation as a biomarker. https://doi.org/10.1186/s12885-021-08242-4 [Abstract]. 21, 510.
Kwan EM, Dai C, Fettke H, Hauser C, Docanto MM, Bukczynska P, Ng N, Foroughi S, Graham LK, Mahon K, Tan W, Wang X, Zhao Z, Zheng T, Zhou K, Yu J, Du P, Horvath LG, Jia S, Kohli M, Azad AA (2021). Plasma Cell–Free DNA Profiling of PTEN-PI3K-AKT Pathway Aberrations in Metastatic Castration-Resistant Prostate Cancer. JCO Precision Oncology, (5), 622-637.
Stringer-Reasor EM, May JE, Olariu E, Caterinicchia V, Li Y, Chen D, Della Manna DL, Rocque GB, Vaklavas C, Falkson CI, Nabell LM, Acosta EP, Forero-Torres A, Yang ES (2021). An open-label, pilot study of veliparib and lapatinib in patients with metastatic, triple-negative breast cancer. . Breast Cancer Res, 23(1).
Kerrigan K, Puri S, Sinnott J, Haaland B, Akerley W, Patel S (2021). Management of Patients with EGFR and ALK-Mutated Advanced Non-Small Cell Lung Cancer Post-TKI Therapy – A Real-World Survival Analysis [Abstract]. 16(3), S690.
Kerrigan K, Chipman J, Jo YJ, Haaland B, Johnson E, Puri S, Varghese T, Akerley W, Patel S (2021). Real-World Survival Outcomes of Patients with Malignant Pleural Mesothelioma by Choice of Second-line Therapy [Abstract]. 16(3), S57-S698.
Puri S, Patel S, Chalmers A, Kerrigan K, Loertscher E, George S, Boucher K, Akerley W (2021). Phase 1b Study to Evaluate the Safety and Efficacy of Osimertinib in Combination with Ipilimumab in EGFR Mutated NSCL [Abstract]. 16(3), S344.
Kerrigan K, Chan J, Vagher J, Kohlmann W, Naumer A, Anson J, Low S, Schiffman J, Maese L (2021). Lung Cancer in Li Fraumeni Syndrome. JCO Precision Oncology. Mar 2021. DOI: 10.1200/PO.20.00468. JCO Precis Oncol.
Neal J, Lim F, Felip E, Gentzler R, Patel S, Baranda J, Fang B, Squillante C, Simonelli M, Werneke S, Curran D, Aix SP (2021). Cabozantinib Plus Atezolizumab in NSCLC Patients Previously Treated with a Checkpoint Inhibitor: Results from COSMIC 021 [Abstract]. 16(3), S230-S231.
Fitzgerald L, Sinnott J, Trunk A, Chalmers A, Akerley W, Patel S (2021). Real World Outcomes of Advanced Non-Small Cell Lung Cancer (NSCLC) With Attention to Carboplatin Area Under the Curve (AUC) = 5 Versus 6 [Abstract]. 16(3), S238-S239.
Kerrigan K, Chipman J, Jo YJ, Haaland B, Johnson E, Puri S, Varghese T, Akerley W, Patel S (2021). Real-World Survival Outcomes of Patients with Malignant Pleural Mesothelioma by Physician’s Choice of First-line Platinum Chemotherapy. 2020 World Conference on Lung Cancer. [Abstract]. 16(3), S122-S123.
Kerrigan K, Wang X, Haaland B, Adamson B, Patel S, Puri S, Akerley W (2021). Real World Characterization of Advanced Non-Small Cell Lung Cancer in Never Smokers by Actionable Mutation Status. doi: https://doi.org/10.1016/j.cllc.2021.01.013 [Abstract].
Hu-Lieskovan S, Malouf GG, Jacobs I, Chou J, Liu L, Johnson ML (2021). Addressing resistance to immune checkpoint inhibitor therapy - an urgent unmet need. [Review]. Future Oncol.
Patel SB, Tuan J (2021). A Community Perspective: Latest 340B Program’s Effect on Cancer Centers. https://dailynews.ascopubs.org/do/10.1200/ADN.21.200434/full/.
Sohal D, Duong MT, Chang R, Xue Y, Delman D, Garrido-Laguna I, Mulvihill SJ, Affolter K, Washington MK, Beg MS, Wang-Gillam A, Wade JL, Gandhi N, Ahmad SA, Lowy AM, Chiorean EG, Guthrie KA, Hochster HS, Philip PA, Beatty GL (2021). Immunologic predictors of therapeutic response to neoadjuvant chemotherapy for pancreatic ductal adenocarcinoma (PDA) in SWOG S1505. [Abstract]. 39(2021), (suppl 3; abstr 419).
Naqash AR, Kihn-Alarcon AJ, Stavraka C, Kerrigan K, Vareki M, Pinato DJ, Puri S (2021). The Role of Gut Microbiome in Modulating Response to Immune Checkpoint Inhibitor Therapy in Cancer. Ann Transl Med.
Parsons M, Lloyd S, Johnson SB, Scaife CL, Garrido-Laguna I, Tao R (2021). The implications of treatment delays in adjuvant therapy for cholangiocarcinoma patients. [Abstract]. 39(2021), (suppl 3: abstr 291).
Kerrigan K, Wang X, Haaland B, Adamson B, Patel S, Puri S, Akerley W (2021). Real World Characterization of Advanced Non-Small Cell Lung Cancer in Never Smokers by Actionable Mutation Status. Clin Lung Cancer.
Miotke L, Nevala-Plagemann CD, Ying J, Florou V, Haaland B, Garrido-Laguna I (2021). Real-world outcomes in recurrent versus de novo metastatic pancreatic adenocarcinoma. [Abstract]. 39(2021), (suppl 3: abstr 387).
Sohal D, Duong MT, Chang R, Xue Y, Delman D, Garrido-Laguna I, Mulvihill SJ, Affolter K, Washington MK, Beg MS, Wang-Gillam A, Wade JL, Gandhi N, Ahmad SA, Lowy AM, Chiorean EG, Guthrie KA, Hochster HS, Philip PA, Beatty GL (2021). Immunologic predictors of therapeutic response to neoadjuvant chemotherapy for pancreatic ductal adenocarcinoma (PDA) in SWOG S1505. [Abstract]. 39(2021), (suppl 3; abstr 419.
Poran A, Scherer J, Bushway ME, Besada R, Balogh KN, Wanamaker A, Williams RG, Prabhakara J, Ott PA, Hu-Lieskovan S, Khondker ZS, Gaynor RB, Rooney MS, Srinivasan L (2020). Combined TCR Repertoire Profiles and Blood Cell Phenotypes Predict Melanoma Patient Response to Personalized Neoantigen Therapy plus Anti-PD-1. Cell Reports Medicine, 1(8).
Janku F, Park H, Call SG, Madwani K, Oki Y, Subbiah V, Hong DS, Naing A, Velez-Bravo VM, Barnes TG, Hagemeister FB, Falchook GS, Karp DD, Wheler JJ, Piha-Paul SA, Garrido-Laguna I, Shpall EJ, Fayad LE, Neelapu SS, Meric-Bernstam F, Kurzrock R, Fanale MA (2020). Safety and Efficacy of Vorinostat Plus Sirolimus or Everolimus in Patients with Relapsed Refractory Hodgkin Lymphoma. Clin Cancer Res, 1(26(21)), 5579-5587.
Meza L, Bergerot PG, Agarwal N, Pal SK (2020). Is there a role for novel TKI/ICI combinations in metastatic renal cell carcinoma? Definitely maybe. PMID: 33121996. Annals of Oncology.
Yung Lyou, Petros Grivas, Jonathan E Rosenberg, Jean Hoffman-Censits, David I Quinn, Daniel P Petrylak, Matthew Galsky, Ulka Vaishampayan, Ugo De Giorgi, Sumati Gupta, Howard Burris, Jessica Rearden, Ai Li, Hao Wang, Maribel Reyes, Susan Moran, Siamak Daneshmand, Dean Bajorin, Sumanta K Pal (2020). Hyperphosphatemia Secondary to the Selective Fibroblast Growth Factor Receptor 1-3 Inhibitor Infigratinib (BGJ398) Is Associated with Antitumor Efficacy in Fibroblast Growth Factor Receptor 3-altered Advanced/Metastatic Urothelial Carcinoma PMID: 32847703 DOI: 10.1016/j.eururo.2020.08.002 Yung Lyou et al. Eur Urol.2020. Eur Urol 2020 Aug 23;S0302-2838(20)30616-3.doi: 10.1016/j.eururo.2020.08.002. Online ahead of print. . Eur Urol, 20(S0302).
Shilpa Gupta, Guru Sonpavde, Christopher J Weight, Bradley Alexander McGregor, Sumati Gupta, Benjamin Louis Maughan, Xiao X Wei, Ewan Gibb, Bharat Thyagarajan, David Johnson Einstein, Christopher B Dechet, William Thomas Lowrance, Paari J Murugan, Kerry L Kilbridge, Neeraj Agarwal, Elai Davicioni, Markus Eckstein, Matthew Mossanen, Mark A Preston, and Badrinath R Konety (2020). Pl Results from BLASST-1 (Bladder Cancer Signal Seeking Trial) of nivolumab, gemcitabine, and cisplatin in muscle invasive bladder cancer (MIBC) undergoing cystectomy. [Abstract]. 38(6_suppl), 439-439.
Torrejon DY, Abril-Rodriguez G, Champhekar AS, Tsoi J, Campbell KM, Kalbasi A, Parisi G, Zaretsky JM, Garcia-Diaz A, Puig-Saus C, Cheung-Lau G, Wohlwender T, Krystofinski P, Vega-Crespo A, Lee CM, Mascaro P, Grasso CS, Berent-Maoz B, Comin-Anduix B, Hu-Lieskovan S, Ribas A (2020). Overcoming Genetically Based Resistance Mechanisms to PD-1 Blockade. Cancer Discov, 10(8), 1140-1157.
Chae YK, Hong F, Vaklavas C, Cheng HC, Hammerman P, Mitchell EP, Zwiebel JA, Ivy SP, Gray RJ, Li S, McShane LM, Rubinstein LV, Patton D, Williams PM, Hamilton SR, Mansfield A, Conley BA, Arteaga CL, Harris LN, ODwyer PJ, Chen AP, Flaherty KT (2020). A Phase II Study of AZD4547 in Patients with Tumors harboring Aberrations in the FGFR Pathway: Results from the NCI-MATCH Trial (EAY131) Sub-protocol W. J Clin Oncol, 38(21), 2407-2417.
Florou V, Nevala-Plagemann C, Barber K, Mastroianni J, Cavalieri C, Garrido-Laguna I (June 2020). Immune checkpoint inhibition re-challenge after a planned treatment interruption in patients with pancreatic adenocarcinoma with mismatch repair deficient tumors. [Abstract]. Proceedings of the American Association for Cancer Research, June 2020.
Florou V, Nevala-Plagemann C, Mulvihill S, Garrido-Laguna I (June 2020). Pancreatic acinar carcinoma - a rare entity with a targetable BRAF V600E mutation. [Abstract]. Proceedings of the American Association for Cancer Research, June 2020.
Vaishnavi A, Scherzer M, Kinsey C, Garrido-Laguna I, McMahon M (2020). Combined TRKA and MEK1/2 Inhibition Forestalls the Onset of Acquired Resistance in a New Preclinical Model of NTRK1+ Pancreatic Cancer. [Abstract].
Channaoui N, Khan A, Wiesman C et al (2020). Summary report of the 2019 Diversity and Inclusion Task Force of the National Society of Genetic Counselors. J Genet Couns.
Praful Ravi, Gregory Russell Pond, Leonidas Nikolaos Diamantopoulos, Rohit K Jain, William Paul Skelton, Sumati Gupta, Jonathan David Tward, Kathleen Olson, Parminder Singh, Camilla Marisa Grunewald, Guenter Niegisch, Jae-Lyun Lee, Andrea Gallina, Marco Bandini, Andrea Necchi, Matthew Mossanen, Bradley Alexander McGregor, Catherine Curran, Petros Grivas, and Guru Sonpavde (6/2020). Dissecting outcomes of patients (pts) with <ypT2N0 disease after neoadjuvant chemotherapy (NAC) for muscle invasive bladder cancer (MIBC): Results from a large, international, multicenter collaboration. [Abstract]. 38(15_suppl), 5043-5043.
Benjamin Louis Maughan, Andrew W Hahn, Roberto Nussenzveig, John Hoffman, Kathryn Morton, Sumati Gupta, Julia Anne Batten, Jared Thorley, Josiah Hawks, Victor Sacristan Santos, Gayatri Nachaegari, Xuechen Wang, Kenneth M Boucher, Benjamin Haaland, and Neeraj Agarwal (6/2020). Randomized phase II trial of radium-223 (RA) plus enzalutamide (EZ) versus EZ alone in metastatic castration-refractory prostate cancer (mCRPC): Long-term follow up of secondary endpoints. [Abstract]. 38(6_suppl), 125-125.
Sergiusz Wesolowski Roberto Nussenzveig, Victor Sacristan Santos, John Esther, Divyam Goel, Umang Swami, Sumati Gupta, Benjamin Louis Maughan, Mark Yandell, Petros Grivas, and Neeraj Agarwal (6/2020). Genomic correlates of response to PD-1 axis inhibitors (IO) in metastatic urothelial cancer (mUC) using explainable artificial intelligence (AI). [Abstract]. 38(6_suppl), 570-570.
Lesli Ann Kiedrowski, Roby Antony Thomas, Nicholas J Vogelzang, Guru Sonpavde, Sumati Gupta, Theodore Stewart Gourdin, Bishoy Morris Faltas, Rebecca Nagy, Richard B Lanman, and Petros Grivas (6/2020). FGFR2/3 genomic alterations (GA) in cell-free (cf)DNA from patients (pts) with advanced urothelial carcinoma (aUC). [Abstract]. 38(6_suppl), 565-565.
Yung Lyou, Petros Grivas, Jonathan E Rosenberg, Jean H Hoffman-Censits, David I Quinn, Daniel Peter Petrylak, Matt D Galsky, Ulka N Vaishampayan, Ugo De Giorgi, Sumati Gupta, Howard A Burris, Jessica Rearden, Yining Ye, Hao Wang, Susan Moran, Siamak Daneshmand, Dean F Bajorin, and Sumanta K Pal (06/2020). Relationship between hyperphosphatemia with infigratinib (BGJ398) and efficacy in FGFR3-altered advanced/metastatic urothelial carcinoma (aUC). [Abstract]. 38(6_suppl), 576-576.
Benjamin Louis Maughan, Roberto Nussenzveig, Umang Swami, Sumati Gupta, and Neeraj Agarwal (06/2020). Prospective trial of nivolumab (Nivo) plus radium-223 (RA) in metastatic castration-resistant prostate cancer (mCRPC) evaluating circulating tumor DNA (ctDNA) levels as a biomarker of response. [Abstract]. 38(6_suppl), TPS267-TPS267.
Benjamin Louis Maughan, Andrew W Hahn, Roberto Nussenzveig, John Hoffman, Kathryn Morton, Sumati Gupta, Julia Anne Batten, Jared Thorley, Josiah Hawks, Victor Sacristan Santos, Gayatri Nachaegari, Xuechen Wang, Kenneth M Boucher, Benjamin Haaland, and Neeraj Agarwal (6/2020). Randomized phase II trial of radium-223 9RA) plus enzalutamide (EZ) versus EZ alone in metastatic castration-refractory prostate cancer (mCRPC): Long-term follow up of secondary endpoints. [Abstract]. 38(6_suppl), 125-125.
Benjamin Louis Maughan, Alejandro Sanchez, Brock B ONeil, William Thomas LowranceChristopher B Dechet, Danel Joseph Albertson, Deepika Sirohi, Sumati Gupta, Umang Swami, and Neeraj Agarwal (6/2020). A phase 1b/II trial of perioperative intratumoral MVA-BN-brachyury (MVA) plus systemic PROSTVAC and atezolizumab (Atezo) for intermediate-risk and high-risk localized prostate cancer (AteoVax). [Abstract]. 38(6_suppl), TPS382-TPS382.
Petros Grivas, Yohann Loriot, Susan Feyerabend, Rafael Morales-Barrera, Min Yuen Teo, Nicholas J Vogelzang, Enrique Grande, Yousef Zakharia, Nabil Adra, Ajjai Shivaram Alva, Andrea Necchi, Sumati Gupta, Debra Hannah Josephs, Alejo Rodriguez-Vida, Sandy Srinivas, Kenton Wride, Daleen Thomas, Rachel Dusek, Dale L Nepert, and Simon Chowdhury (06/2020). Rucaparib for recurrent, locally advanced, or metastatic urothelial carcinoma (mUC): Results from ATLAS, a phase II open-label trial. [Abstract]. 38(6_suppl), 440-440.
Lin E, Hahn AW, Nussenzveig R, Wesolowski S, Maughan BL, McFarland TR, Rathi N, Sartor AOO, Sonpavde G, Swami U, Kohli M, Rich TA, Yandell M, Agarwal N (2020). Genomic alterations associated with the progression from castration-sensitive to castration-resistant metastatic prostate cancer based on machine learning analysis of cell-free DNA genomic profile (suppl; abstr e17596). [Abstract]. 38.
Meric-Bernstam F, Calvo E, Moreno V, Chung HC, Park YH, Bang Y-J, Rosen LS, Mita MM, Garrido-Laguna I, Leung ACF, Dube H, Zhong W, Chen X, Dawaher R, Curigliano G (May 2020). A phase I dose escalation study evaluating the safety and tolerability of a novel anti-HER2 antibody-drug conjugate (PF‑06804103) in patients with HER2-positive solid tumors. [Abstract]. 38(suppl; abstr 1039 American Society of Clinical Oncology Annual Meeting).
Swami U, Sinnott JA, Haaland B, Maughan BL, Rathi N, McFarland TR, Kohli M, Nussenzveig R, Pal SK, Agarwal N (2020). Overall survival (OS) with docetaxel (D) vs novel hormonal therapy (NHT) with abiraterone (A) or enzalutamide (E) after a prior NHT in patients (Pts) with metastatic prostate cancer (mPC): Results from a real-world dataset (suppl; abstr 5537). [Abstract]. 38.
Garrido-Laguna I, Dillon PM, Anthony SP, Janat-Amsbury M, Ashenbramer N, Warner SL, Mouritsen L, Wade ML, Whatcott C, Bearss D, Fu S (Mary 2020). A phase I, first-in-human, open-label, dose‑escalation, safety, pharmacokinetic, and pharmacodynamic study of oral TP‑3654 administered daily for 28 days to patients with advanced solid tumors. [Abstract]. May 2020.
Neal JW, Lim FL, Felip E, Gentzler RD, Patel SB, Baranda J, Fang B, Squillante CM, Simonelli M, Werneke S, Curran D, Aix SP (2020). Cabozantinib in combination with atezolizumab in non-small cell lung cancer (NSCLC) patients previously treated with an immune checkpoint inhibitor: Results from cohort 7 of the COSMIC-021 study. (suppl) abstr 9610 [Abstract]. 38.
Pokorny R, McPherson JP, Grossmann KF, Luckett C, Voorhies BN, Sageser DS, Wallentine J, Tolman Z, Hu-Lieskovan S, Swami U (2020). Clinical outcomes with early-elective discontinuation of PD-1 inhibitors (PDi) at one year in patients (pts) with metastatic melanoma (MM) (suppl; abstr 10048). [Abstract]. 38.
Swami U, Haaland B, Maughan BL, Nussenzveig R, Esther J, Kessel A, Pal SK, Grivas P, Agarwal N (2020). Comparative effectiveness of second-line (2L) single-agent atezolizumab (A), nivolumab (N), and pembrolizumab (P) in patients (Pts) with locally advanced or metastatic urothelial cancer (aUC) who progressed on platinum-based systemic chemotherapy (plat-chemo): Results from a real-world dataset (suppl; abstr 5032). [Abstract]. 38.
Braithwaite M, Nevala-Plagemann CD, Baron K, Haaland B, Pappas LM, Garrido-Laguna I (May 2020). Real-world outcomes of patients with BRAF-mutated mCRC treated in the United States. [Abstract]. 38(suppl; abstr 4030 American Society of Clinical Oncology Annual Meeting).
McKean W, Moser J, Rimm D, Hu-Lieskovan S (2020). Biomarkers in Precision Cancer Immunotherapy: Promise and Challenges. In ASCO Educational Book 40 (2020) (pp. e275-e291).
Kim R, Sanoff H, Poklepovic A, Soares H, Kim J, Lyu J, Liu Y, Kim D (2020). A multi-institutional phase II trial of regorafenib in refractory advanced biliary tract cancer. Accepted. . Cancer.
Vaklavas C, Roberts BS, Varley KE, Lin NU, Liu MC, Rugo HS, Puhalla S, Nanda R, Storniolo AM, Carey LA, Saleh MN, Li Y, Delossantos JF, Grizzle WE, LoBuglio AF, Myers RM, Forero-Torres A on behalf of the Translational Breast Cancer Research Consortium (2020). TBCRC 002: A phase II, randomized, open label trial of preoperative letrozole with or without bevacizumab in post-menopausal women with newly diagnosed stage II/III hormone receptor positive and HER2 negative breast cancer. Breast Cancer Res, 22(1).
Bensimon AG, Zhong Y, Swami U, Briggs A, Young J, Feng Y, Song Y, Signorovitch J, Adejoro O, Chakravarty A, Chen M, Perini RF, Geynisman DM (2020). Cost-effectiveness of pembrolizumab in combination with axitinib as first-line treatment for advanced renal cell carcinoma [Abstract]. 38.
Maughan BL, Sanchez A, ONeil BB, Lowrance WT, Dechet CB, Albertson DJ, Sirohi D, Gupta S, Swami U, Agarwal N (2020). A phase Ib/II trial of perioperative intratumoral MVA-BN-brachyury (MVA) plus systemic PROSTVAC and atezolizumab (Atezo) for intermediate-risk and high-risk localized prostate cancer (AtezoVax) [Abstract]. 38.
Wesolowski S, Nussenzveig R, Santos VS, Esther J, Goel D, Swami U, Gupta S, Maughan BL, Yandell M, Grivas P, Agarwal N (2020). Genomic correlates of response to PD-1 axis inhibitors (IO) in metastatic urothelial cancer (mUC) using explainable artificial intelligence (AI) [Abstract]. 38.
Swami U, Isaacsson Velho PI, Nussenzveig R, Santos VS, Erickson S, Dharmaraj D, Alva AS, Vaishampayan UN, Esther J, Hahn AW, Maughan BL, Antonarakis ES, Agarwal N (2020). Impact of somatic SPOP (Speckle-Type POZ protein) mutation (mtSPOP) on response to systemic therapy and survival outcome in men with de novo metastatic castration-sensitive prostate cancer (d-mCSPC). [Abstract]. 38.
Maughan BL, Nussenzveig R, Swami U, Gupta S, Agarwal N (2020). Prospective trial of nivolumab (Nivo) plus radium-223 (RA) in metastatic castration-resistant prostate cancer (mCRPC) evaluating circulating tumor DNA (ctDNA) levels as a biomarker of response [Abstract]. 38.
Lin E, Wesolowski S, Nussenzveig R, McFarland TR, Swami U, Maughan BL, Yandell M, Agarwal N (2020). Identification of genomic alterations in signaling pathways associated with poor survival in newly diagnosed metastatic prostate cancer (mCSPC) using artificial intelligence (AI) [Abstract]. 38.
Esther J, Swami U, Chipman J, McFarland TR, Hahn AW, Sirohi D, Sharma P, Nussenzveig R, Agarwal N, Maughan BL (2020). Genomic alterations in visceral versus nonvisceral “metastatic” site tumor tissue in metastatic prostate cancer (mPC) [Abstract]. 38.
Hahn AW, Kessel A, McFarland TR, Swami U, Nussenzveig R, Esther J, Goel D, Sirohi D, Maughan BL, Agarwal N (2020). Response to systemic therapy and survival outcomes in de-novo (D1) metastatic castration-sensitive prostate cancer (mCSPC) versus mCSPC with prior local therapy (D0 [Abstract]. 38.
Parisi G, Saco J, Salazar F, Tsoi J, Krystofinski P, Puig Saus C, Zhang R, Zhou J, Cheung-Lau G, Garcia AJ, Grasso CS, Tavar R, Hu-Lieskovan S, Mackay S, Zalevsky J, Bernatchez C, Diab A, Wu A, Comin-Anduix B, Charych DH, Ribas A (Jan 2020). Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist. Nat Commun, 11(1), 660.
Pauley K, Koptiuch C, Greenberg S, Gammon A, Nevala-Plagemann C, Vagher J, Espinel W, Gilcrease GW, Kohlmann W, Garrido-Laguna I (2020). Case series examining somatic test results for patients with hereditary cancer syndromes associated with gastrointestinal cancer risk [Abstract]. 38(2020), (suppl 4; abstr 680).
Baron K, Nevala-Plagemann CD, Moser J, Haaland B, Wang X, Garrido-Laguna I (2020). Survival outcomes based on sequence of therapy using FOLFIRINOX and nab-paclitaxel + gemcitabine in metastatic pancreatic ductal adenocarcinoma [Abstract]. 38(2020), (suppl 4; abstr 657).
Parsons M, Tao R, Lloyd S, Johnson SB, Scaife CL, Garrido-Laguna I, Varghese T (2020). Refusal of surgery results in inferior survival in esophageal cancer [Abstract]. 38(2020), (suppl 4; abstr 364).
Vaklavas C, Blume SW, Grizzle WE (2020). Hallmarks and Determinants of Oncogenic Translation Revealed by Ribosome Profiling in Models of Breast Cancer. . Translational Oncology, 13(2), 452-470.
Rieth JM, Swami U, Greenlee J, Zanaty M, Bossler A, Jennings B, Henry M, Vanneste M, Mott S, Milhem MM (2019). Impact of surgery on outcomes in melanoma patients with brain metastases in the era of immunotherapy. The 16TH International Congress of the Society for Melanoma Research (SMR) [Abstract].
Kaur A, Swami U, Fatima M, Ginn M, Stein J, Gao Y, Zakharia Y, Singh Y (2019). Safety of Immune Checkpoint Inhibitors in Patients Treated for Cancer with Pre-existing Autoimmune Diseases, 2019 ACR/ARP Annual Meeting [Abstract].
Khan A, Cohen S A, Weir C, Greenberg S (2019). Analysis of Key Factors in the Implementation of new Service Delivery Models in Genetic Counseling Practice [Abstract].
Kerrigan, K, Haaland B, Adamson B, Patel S, Akerley W (2019). MA14.09 Real-World Survival of Relapsed Compared to De-Novo Stage IV Diagnosis of Advanced Non-Small Cell Lung Cancer [Abstract]. 14(10), S307-S308.
Kerrigan K, Haaland B, Adamson B, Patel S, Akerley W (2019). P1.01-35 Real World Characterization of Advanced Non-Small Cell Lung Cancer in Never Smokers [Abstract]. 14(10), S369-S370.
Lim F, Ponce S, Patel S, Van Herpen C, Kurkjian C, Lou Y, Liu Y, Ramsingh G, Pal S, Neal J (2019). P1.01-113 Phase 1b Trial of Cabozantinib or Cabozantinib Plus Atezolizumab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) [Abstract]. 14(10), S405-S406.
Zhu Y, Smith DJ, Zhou Y, Li YR, Yu J, Lee D, Wang YC, Di Biase S, Wang X, Hardoy C, Ku J, Tsao T, Lin LJ, Pham AT, Moon H, McLaughlin J, Cheng D, Hollis RP, Campo-Fernandez B, Urbinati F, Wei L, Pang L, Rezek V, Berent-Maoz B, Macabali MH, Gjertson D, Wang X, Galic Z, Kitchen SG, An DS, Hu-Lieskovan S, Kaplan-Lefko PJ, De Oliveira SN, Seet CS, Larson SM, Forman SJ, Heath JR, Zack JA, Crooks GM, Radu CG, Ribas A, Kohn DB, Witte ON, Yang L (Oct 2019). Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell, 25(4), 542-557.e9.
Sacristan Santos V, Esther J, Maughan B, Wesolowski S, Lin E, Hahn A, Sirohi D, Rathi N, Swami U, Nussenzveig R, Agarwal N (2019). Molecular characterization of metastatic urothelial carcinoma (mUC) in prior or current smokers (PCS) vs non-smokers (NS [Abstract]. 30(5).
Moser J, Wei G, Colonna S, Grossmann KF, Patel S, Hyngstrom J (2019). Comparative-effectiveness of pembrolizumab vs nivolumab for patients with metastatic melanoma [Abstract]. 30.
Coleman RL, Fleming GF, Brady MF, Swisher EM, Steffensen KD, Friedlander M, Okamoto A, Moore KN, Ben-Baruch N, Werner TL, Oaknin A, Nam JH, Leath CA, Nicum S, Cella D, Sullivan DM, Ansell PJ, Dinh MH, Aghajanian C, Bookman MA (2019). VELIA/GOG-3005: Integration of veliparib with front-line chemotherapy+maintenance in women with high-grade serous carcinoma of ovarian, fallopian tube, or primary peritoneal origin [Abstract]. 30, 895-896.
Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen Y, Ciombor KK, Cohen SA, Cooper HS, Deming DA, Garrido-Laguna I, Grem JL, Hoffe SE, Hubbard J, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Nurkin S, Overman MJ, Parikh A, Patel H, Pedersen KS, Saltz LB, Schneider C, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Johnson-Chilla A, Gregory KM, Gurski LA (2019). Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw, 17(9), 1109-1133.
Saif MW, Parikh R, Ray D, Kaye JA, Kurosky SK, Thomas K, Ramirez RA, Halfdanarson TR, Beveridge TJR, Mirakhur B, Nagar SP, Soares HP (2019). Medical record review of transition to lanreotide following octreotide for neuroendocrine tumors. J Gastrointest Oncol, 10(4), 647-687.
Siena S, Demetri G, Doebele R, Chae Y, Conkling P, Garrido-Laguna I, Garrido P, Rolfo C, Sigal D, Eng S, Simmons B, Ye C, Ciardiello F (July 2019). Entrectinib in NTRK-fusion positive gastrointestinal cancers: integrated analysis of patients enrolled in three trials (STARTRK-2, STARTRK-1, and ALKA-372-001) [Abstract]. 2019(Abstract #0-024).
Nevala-Plagemann C, Moser J, Gilcrease GW, Garrido-Laguna I (Jul 2019). Survival of patients with metastatic HER2 positive gastroesophageal cancer treated with second-line chemotherapy plus trastuzumab or ramucirumab after progression on frontline chemotherapy plus trastuzumab [Abstract]. J Clin Oncol, 4(4), e000539.
Nevala-Plagemann C, Moser J, Gilcrease GW, Garrido-Laguna I (July 2019). Survival of patients with metastatic HER2 positive gastro-oesophageal cancer treated with second-line chemotherapy plus trastuzumab or ramucirumab after progression on front-line chemotherapy plus trastuzumab. ESMO Open, 4(4), e000539.
Al-Toubah T, Schell M, Cives M, Zhou JM, Soares H, Strosberg JR (2019). A Phase II Study of Ibrutinib in Advanced Neuroendocrine Neoplasms. Neuroendocrinology, doi: 10.1159/000502383.
Hu-Lieskovan S, Ott P, Naing A, Gates S, Kohler V, Curran R, Besada R, Bushway M, Scherer J, Balogh K, Scuito T, Ting Y, Rooney M, Harjanto D, Huang Z, Huang Y, Ware Y, Lamb A, Cleary L, Moles M, Gaynor R, Goldstein M, Brail L, Greshock J, Srinivasan L (July 2019). The personalized vaccine, NEO-PV-01 with anti-PD1, induces neoantigen-specific de novo immune responses in patients with advanced metastatic melanoma: correlations with clinical outcome [Abstract]. 79(13 Supplement), Abstract 942.
Hu-Lieskovan S, Braiteh F, Grilley-Olson J, Potluri S, Wang X, Forgie A, Bonato V, Chou J, Johnson M (July 2019). Predictive biomarkers and pharmacodynamic (PD) changes in tumor RNA expression in a phase I study of anti PD-1 monoclonal antibody (mAb) PF-06801591 [Abstract]. 79(13 Supplement), Abstract CT046.
Chiorean EG, Guthrie KA, Philip PA, Swisher EM, Jalikis F, Pishvaian MJ, Berlin J, Noel MS, Suga JM, Garrido-Laguna I, Cardin DB, Lew DL, Lowy AM, Hochster HS (2019 Annual ASCO Meeting). Randomized phase II study of second-line modified FOLFIRI with PARP inhibitor ABT-888 (Veliparib) (NSC-737664) versus FOLFIRI in metastatic pancreatic cancer (mPC): SWOG S1513 [Abstract]. 37(2019), (suppl; abstr 4014).
Johnson ML, Braiteh F, Grilley-Olson JE, Chou J, Davda J, Forgie A, Li R, Jacobs I, Kazazi F, Hu-Lieskovan S (May 2019). Assessment of Subcutaneous vs Intravenous Administration of Anti-PD-1 Antibody PF-06801591 in Patients With Advanced Solid Tumors: A Phase 1 Dose-Escalation Trial. JAMA Oncol.
Yap T, Papadopoulos K, LoRusso P, Wong D, Hu-Lieskovan S, Holz J-B (May 2019). A first-in-human phase I study of FS118, an anti-LAG-3/PD-L1 bispecific antibody in patients with solid tumors that have progressed on prior PD-1/PD-L1 therapy [Abstract]. 37(15 Supplement), TPS2652.
Hu-Lieskovan S, Lisberg A, Zaretsky J, Wells D, Han M, Shintaku I, Wolf B, Abarca P, Slamon D, Goldman JW, Dubinett S, Ribas A, Garon EB (May 2019). Tumor characteristics associated with benefit from pembrolizumab in advanced non-small cell lung cancer. Clin Cancer Res.
Fares CM, Van Allen EM, Drake CG, Allison JP, Hu-Lieskovan S (Jan 2019). Mechanisms of Resistance to Immune Checkpoint Blockade: Why Doesn't Checkpoint Inhibitor Immunotherapy Work for All Patients? In ASCO Educational Book 39 (2019) (pp. 147-164).
Chi KN, Agarwal N, Bjartell A, Chung BH, Gomes AJPS, Given RW, Soto AJ, Merseburger AS, Ozguroglu M, Uemura H, Ye D, Deprince K, Naini V, Li J, Cheng S, Yu MK, Zhang K, Larsen JS, McCarthy SA, Chowdhury S (2019). First results from TITAN: A phase III double-blind, randomized study of apalutamide (APA) versus placebo (PBO) in patients (pts) with metastatic castration-sensitive prostate cancer (mCSPC) receiving androgen deprivation therapy (ADT) (suppl; abstr 5006) [Abstract]. 37.
Rathkopf DE, Saleh MN, Tsai FYC, Bilen MA, Rosen LS, Gottardis M, Infante JR, Adams BJ, Liu L, Theuer CP, Freddo JL, Agarwal N (2019). An open label phase 1/2A study to evaluate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of TRC253, an androgen receptor antagonist, in patients with metastatic castration-resistant prostate cancer (suppl; abstr e16542) [Abstract]. 37.
Appleman LJ, Puligandla M, Pal SK, Harris W, Agarwal N, Costello BA, Ryan CW, Pins M, Kolesar J, Vaena DA, Parikh RA, Hashmi M, Dutcher JP, DiPaola RS, Haas NB, Carducci MA (2019). Randomized, double-blind phase III study of pazopanib versus placebo in patients with mtastatic renal cell carcinoma who have no evidence of disease following metastasectomy: A trial of the ECOG-ACRIN cancer research group (E2810) (suppl; abstr 4502). [Abstract]. 37.
Hahn AW, Lin E, Esther J, Anderson N, Rathi N, Yandell M, Maughan BL, Agarwal N (2019). Genomic landscape of metastatic hormone senstitive prostate cancer (mHSPC) vs. metastatic castration-refractory prostate cancer (mCRPC) by circulating tumor DNA (ctDNA) (suppl; abstr 5043) [Abstract]. 37.
Grivas P, Puligandla M, Cole S, Courtney KD, Dreicer R, Gartrell BA, Cetnar JP, Dallera M, Galsky MD, Jain RK, Maughan BL, Agarwal N, Koshkin VS, Hahn NM, Carducci MA (2019). PrE0807 phase Ib feasibility trial of neoadjuvant nivolumab (N)/lirilumab (L) in cisplatin-ineligible muscle-invasive bladder cancer (BC) (suppl; abstr TPS4594). [Abstract]. 37.
Lin E, Nussenzveig R, Hahn AW, Yandell M, Harshman LC, Agarwal N, Tripathi A (2019). Immune correlates of CD73 expression in patients with urothelial carcinoma (UC) (suppl; abstr 4548) [Abstract]. 37.
Tripathi A, Lin E, Nussenzveig R, Yandell M, Pal SK, Agarwal N (2019). An analysis from The Cancer Genome Atlas database (suppl; abstr e16591) [Abstract]. 37.
Agarwal N, Shore ND, Dunshee C, Karsh LI, Sullivan B, Santo ND, Elmeliegy M, Lin X, Quek RGW, Czibere AG, Fizazi K (2019). TALAPRO-2 (P2) of the placebo-controlled phase 3 study of talazoparib (TALA) with enzalutamide (ENZA) in metastatic castration-resistant prostate cancer (mCRPC) (suppl; abstr TPS5092) [Abstract]. 37.
Lin E, Hahn AW, Sonpavde G, Lilly MB, Nussenzveig R, Ledet E, Pal SK, Grivas P, Rich TA, Raymond VM, Sartor O, Yandell M, Agarwal N (2019). Profiling of genomic alterations in MAPK/ERK signaling in a large cohort of metastatic prostate cancer (mPC) patients (suppl; abstr 5032) [Abstract]. 37.
Bandini M, Pederzoli Filippo, Madison R, Briganti A, Plimack ER, Ross JS, Niegisch G, Yu EY, Bamias A, Agarwal N, Sridhar SS, Rosenberg JE, Bellmunt J, Galsky MD, Gallina A, Salonia A, Montorsi F, Ali SM, Chung J, Necchi A (2019). Squamous-cell carcinoma variant histology (SCC-VH) in muscle-invasive bladder cancer (MIBC): A comprehensive clinical, genomic, and therapeutic assessment from multiple datasets (suppl; abstr 4535) [Abstract]. 37.
Grunewald CM, Henn A, Galsky MD, Plimack ER, Harshman LC, Yu EY, Crabb SJ, Pal SK, Alva AS, Powles T, Giorgi UD, Agarwal N, Bamias A, Ladoire S, Necchi A, Vaishampayan UN, Sternberg CN, Bellmunt J, Baniel J, Niegisch G (2019). Impact of timing of adjuvant chemotherapy following radical cystectomy for bladder cancer on patient survival (suppl; abstr e16017) [Abstract]. 37.
Agarwal N, Shore ND, Dunshee C, Karsh LI, Sullivan B, Santo ND, Elmeliegy M, Lin X, Czibere AG, Fizazi K (2019). Clinical and safety outcomes of TALAPRO-2: A two-part phase III study of talazoparib (TALA) in combination with enzalutamide (ENZA) in metastatic castration-resistant prostate cancer (mCRPC) (suppl; abstr 5076) [Abstract]. 37.
Tagawa ST, Petrylak DP, Grivas P, Agarwal N, Sternberg CN, Hernandez C, Siemon-Hryczyk P, Goswami T, Loriot Y (2019). TROPHY-U-01: A phase II open-label study of sacituzumab govitecan (IMMU-132) in patients with advanced urothelial cancer after progression on platinum-based chemotherapy and/or anti-PD-1/PD-L1 checkpoint inhibitor therapy (suppl; abstr TPS3153) [Abstract]. 37.
Necchi A, Pal SK, Ross JS, Madison R, Agarwal N, Sonpavde G, Joshi M, Yin M, Miller VA, Grivas P, Chung J, Ali SM (2019). Comprehensive genomic profiling (CGP) of upper-tract (UTUC) and bladder (BUC) urothelial carcinoma reveals opportunities for therapeutic and biomarker development (suppl; abstr 4581) [Abstract]. 37.
Tannir NM, Agarwal N, Pal SK, Formiga MN, Guo J, Tagliaferri MA, Hannah AL, Zhang JY, OKeeffe BA, Cho DC (2019). A phase III randomized open label study comparing bempegaldesleukin (NKTR-214) plus nivolumab to sunitinib or cabozantinib (investigator’s choice) in patients with previously untreated advanced renal cell carcinoma(suppl; abstr TPS4595) [Abstract]. 37.
Allen CT, Lee S, Norberg SM, Kovalovsky D, Ye H, Clavijo PE, Hu-Lieskovan S, Schlegel R, Schlom J, Strauss J, Gulley JL, Trepel J, Hinrichs CS (May 2019). Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis. Journal for Immunotherapy of Cancer, 7(1), 119.
Nowicki T, Berent-Maoz B, Cheung-Lau G, Huang RR, Wang X, Tsoi J, Kaplan-Lefko P, Cabrera P, Tran J, Pang J, Macabali M, Garcilazo IP, Carretero IB, Kalbasi A, Cochran A, Grasso C, Hu-Lieskovan S, Chmielowski B, Comin-Anduix B, Singh A, Ribas A (Apr 2019). A Pilot Trial of the Combination of Transgenic NY-ESO-1-reactive Adoptive Cellular Therapy with Dendritic Cell Vaccination With or Without Ipilimumab. Clin Cancer Res, 25(7), 2096-2108.
Tannir NM, Agarwal N, Dawson NA, Motzer RJ, Jacobs CM, Choueiri TK, Hrom JS, Geynisman DM, Davis NB, Figlin RA, OKeeffe MK, Parikh JR, Vaena DA, Liu PY, OKeeffe B, Tran X, Escudier B (2019). CANTATA: Randomized, international, double-blind study of CB-839 plus cabozantinib versus cabozantinib plus placebo in patients with metastatic renal cell carcinoma (suppl 7S; abstr TPS682) [Abstract]. Journal of Clinical Oncology, 37.
Hahn AW, Drake CG, Denmeade SR, Zakharia Y, Maughan BL, Kennedy EP, Link CJ, Vahanian NN, Hammers HJ, Agarwal N (2019). Efficacy of alpha-1,3-galactosyltransferase-expressing allogeneic renal cell carcinoma immunotherapy in patients (pts) with refractory metastatic renal cell carcinoma (mRCC) (suppl 7S; abstr 590) [Abstract]. Journal of Clinical Oncology, 37.
Agarwal N, Pal SK, Lauer RC, Chatta GS, Goel S, Singh P, Sundararajan S, Heaton C, Peterson C, Benaim E, Tagawa ST (2019). Results of a phase II study to evaluate the safety and efficacy of RX-0201 in combination with everolimus in subjects with metastatic renal cell carcinoma (mRCC) (suppl 7S; abstr 646) [Abstract]. Journal of Clinical Oncology, 37.
Pal SK, Vaishampayan UN, Castellano DE, Necchi A, Van Herpen CML, Ramsingh G, Loriot Y, Agarwal N (2019). Phase 1b (COSMIC-021) trial of cabozantinib (C) in urothelial carcinoma (UC) or C in combination with atezolizumab (A) in patients (pts) with UC, castrate resistant prostate cancer (CRPC) or renal cell carcinoma (RCC) (suppl 7S; abstr TPS683) [Abstract]. Journal of Clinical Oncology, 37.
Hahn AW, Haaland B, Rathi N, Dizman N, Maughan BL, Pal SK, Agarwal N (2019). Receipt of systemic therapy in older versus younger patients (pts) with metastatic renal cell carcinoma (mRCC) (suppl 7S; abstr 580) [Abstract]. Journal of Clinical Oncology, 37.
Agarwal N (2019). Why I Attend. 2019 Genitourinary Oncology Symposium (GU ASCO) https://dailynews.ascopubs.org/do/10.5555/ADN.19.190070/full/ [Web]. San Francisco, CA.
Tagawa ST, Petrylak DP, Grivas P, Agarwal N, Sternberg CN, Siemon-Hryczyk P, Goswam T, Loriot Y (2019). TROPHY-u-01: A phase II open-label study of sacituzumab govitecan (IMMU-132) in patients with advanced urothelial cancer after progression on platinum-based chemotherapy and/or anti-PD-1/PD-L1 checkpoint inhibitor therapy (suppl 7S; abstr TPS495) [Abstract]. Journal of Clinical Oncology, 37.
Ko L, Lilly MB, Hahn AW, Nussenzveig R, Moses MM, Ledet E, Manogue C, Cotogno P, Lewis BE, Layton JL, Agarwal N, Sartor AO, Barata PC (2019). Genomic changes of AR in ctDNA prior to enzalutamide in men with mCRPC after abiraterone acetate (suppl 7S; abstr 320) [Abstract]. Journal of Clinical Oncology, 37.
Griswold CR, Bailey EB, Mauser JC, Boucher KM, Agarwal N, Gupta S, Maughan BL (2019). Risk factors for venous thromboembolism (VTE) during chemotherapy in patients with germ cell tumors (GCT) (suppl 7S; abstr 520) [Abstract]. Journal of Clinical Oncology, 37.
Tward JD, ONeil B, Stephenson RA, Agarwal N, Farr T, Petragallo R, Lowrance WT (2019). Survival outcomes for adjuvant or salvage radiation in men with pN+M0 prostate cancer (suppl 7S; abstr 276) [Abstract]. Journal of Clinical Oncology, 37.
Teerlink C, Hahn AW, Esther J, Rathi N, Farnham JM, Agarwal N, Cannon-Albright L (2019). Genome-wide association study of metastatic prostate cancer (suppl 7S; abstr 160) [Abstract]. Journal of Clinical Oncology, 37.
Lin E, Hahn AW, Sonpavde G, Lilly MB, Nussenzveig R, Ledet E, Pal SK, Grivas P, Rich TA, Raymond VM, Sartor AO, Yandell M, Agarwal N (2019). Discovery of targetable mutational signatures in advanced prostate cancer (aPC) using machine learning and next-generation sequencing (NGS) of circulating tumor DNA (ctDNA) (suppl 7S; abstr 226) [Abstract]. Journal of Clinical Oncology, 37.
Pal SK, Szeto C, Reddy SK, Nussenzveig R, Lam RY, Scholz MC, Agarwal N (2019). Concomitant characterization of androgen receptor (AC) and immune checkpoints (ICs) in cell-free (cf) DNA and RNA from patients with metastatic castration resistant prosate cancer (mCRPC) (suppl 7S; abstr 286) [Abstract]. Journal of Clinical Oncology, 37.
Agarwal N, Shore ND, Dunshee C, Karsh LI, Sullivan B, Santo ND, Elmeliegy M, Casey M, Quek RGW, Czibere A, Fizazi K (2019). TALAPRO-2: A two-part, placebo-controlled phase III study of talazoparib (TALA) with enzalutamide (ENZA) in metastatic castration-resistant prostate cancer (mCRPC) (suppl 7S; abstr TPS337) [Abstract]. Journal of Clinical Oncology, 37.
Berry S, Giraldo N, Nguyen P, Green B, Xu H, Ogurtsova A, Soni A, Succaria F, Wang D, Roberts C, Stein J, Engle E, Pardoll D, Anders R, Cottrell T, Taube JM, Tran B, Voskboynik M, Kuo J, Bang YL, Chung HC, Ahn MJ, Kim SW, Perera A, Freeman D, Achour I, Faggioni R, Xiao F, Ferte C, Lemech C, Meric-Bernstam F, Werner T, Hodi S, Messersmith W, Lewis N, Talluto C, Dostalek M, Tao A, McWhirter S, Trujillo D, Luke J, Xu C, BoMarelli, Qi J, Qin G, Yu H, Jenkins M, Lo KM, Halle JP, Lan Y, Taylor M, Vogelzang N, Cohn A, Stepan D, Shumaker R, Dutcus C, Stepan D, Guo M, Schmidt E, Taylor M, Vogelzang N, Di Simone C, Jain S, Richards D, Encarnacion C, Rasco D, Shumaker R, Dutcus C, Stepan D, Guo M, Schmidt E, Taylor M, Vogelzang N, Encarnacion C, Cohn A, Di Simone C, Rasco D, Richards D, Taylor M, Dutcus C, Stepan D, Shumaker R, Guo M, Schmidt E, Mier J, An J, Yang YY, Lee WH, Yang J, Kim JK, Kim HG, Paek SH, Lee JW, Woo J, Kim JB, Kwon H, Lim W, Paik NS, Kim YK, Moon BI, Janku F, Tan D, Martin-Liberal J, Takahashi S, Geva R, Gucalp A, Chen X, Subramanian K, Mataraza J, Wheler J, Bedard P (2019). Correction to: 33rd Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2018). J Immunother Cancer.
Garrido-Laguna I, Krop I, Burris HA 3rd, Hamilton E, Braiteh F, Weise AM, Abu-Khalaf M, Werner TL, Pirie-Shepherd S, Zopf CJ, Lakshminarayanan M, Holland JS, Baffa R, Hong DS (2019). First-in-human, phase I study of PF-06647263, an anti-EFNA4 calicheamicin antibody-drug conjugate, in patients with advanced solid tumors. Int J Cancer.
Vaishnavi A, Scherzer M, Kinsey C, Garrido-Laguna I, McMahon M (2019). MEK1/2 Inhibition Forestalls the Onset of Acquired Resistance to Entrectinib in a New Preclinical Model of TPR-NTRK1 Driven Pancreatic Cancer [Abstract].
Gruhl J, Francis SR, Tao R, Solomon BL, Nevala-Plagemann CD, Garrido-Laguna I, Lloyd S (01/18/2019). The impact of histology (adenocarcinoma vs. SCC) on outcomes in nonmetastatic pancreatic cancer.Presented ASCO 2019 Gastrointestinal Cancers Symposium [Abstract]. J Clin Oncol, 37(2019), suppl 4 abstr 419.
Pelzer U, Bendell JC, Womack MS, Bahary N, Macarulla T, Borazanci EH, Levy DE, Mo G, Ramage SC, Garrido-Laguna I (01/18/2019). A phase Ib study evaluating olaratumab in combination with nab-paclitaxel and gemcitabine in first-line treatment of metastatic pancreatic cancer.Presented AASCO 2019 Gastrointestinal Cancers Symposium [Abstract]. J Clin Oncol, 37(2019), suppl 4; abstr 330.
P Twardowski, J YCWong, SKPal, B LMaughan, P H Frankel, K Franklin, M Junqueira, M RPrajapati, G Nachaegari, D Harwood, N Agarwal (12/28/2018). Randomized phase II trial of Sipuleucel-T immunotherapy preceded by sensitizing radiation therapy and sipuleucel-T alone in patients with metastatic castrate resistant prostate cancer [Abstract]. Cancer Treatment and Research Communications (doi: 10.1016/j.ctarc.2018.100116), 20 December 2018, 100116.
Sirohi D, Smith SC, Agarwal N, Maughan BL (November 2018). Unclassified renal cell carcinoma: diagnostic difficulties and treatment modalities [Abstract]. Dove Medical Press, 2018(10), 205-217.
Hu-Lieskovan S, Govindan R, Naing A, Friedlander T, Margolin K, Lin J, Bhardwaj N, Hellmann M, Srinivasan L, Greshcok J, Moles M, Gaynor R, Goldstein M, Ott P (November 2018). The personal vaccine, NEO-PV-01 with anti-PD1, induces neoantigen-specific de novo tumor-related immunity in patients with advanced cancer [Abstract]. Abstract O7.
Hu-Lieskovan S, Govindan R, Naing A, Griedlander T, Marolin K, Lin J, Bhardwaj N, Hellmann M, Srinivasan L, Greshcok J, Moles M, Gaynor R, Goldstein M, Ott P (November 2018). PAK4 inhibition reverses immune cell exclusion and overcomes resistance to checkpoint blockade therapy [Abstract]. Abstract O39.
Evans E, Bussler H, Mallow C, Reilly C, Torno S, Scrivens M, Howell A, Balch L, Leonard J, Fisher T, Allen C, Clavijo P, Lesinki G, Wu C, Hu-Lieskovan S, Ribas A, Greengard E, Smith E, Zauderer M (November 2018). Reprogramming suppressive myeloid cells in tumor microenvironment with pepinemab, first-in-class Semaphorin 4D Mab, enhances combination immunotherapy [Abstract]. O20.
Sharma S, Moore KN, Mettu NB, Garrido-Laguna I, Ulahannan SV, Khemka V, Kapoun A, Faoro L, Bendell J (Nov 2018). Initial results from a phase 1a/b study of etigilimab (OMP-313M32), an anti-T cell immunoreceptor with lg and ITIM domains (TIGIT) antibody, in advanced solid tumors [Abstract]. SITC 2018, Washington, D.C.
Coman G, Moser J, Hyngstrom J, Grossmann K, Patel SB, Colonna S, Andtbacka R (2018). Overall Survival of Patients Treated with Single Agent Ipilimumab or Combination Nivolumab and Ipilimumab in Second Line Setting After Progression on Frontline Anti-PD-1 Therapy [Abstract].
Solomon BL, Garrido-Laguna I (1/11/2018). Novel Therapies in Pancreatic Cancer: Opportunities and Challenges for Precision Medicine. 2018 Gastrointestinal Cancers Symposium Daily News (January 11, 2018). San Francisco.
Bethune MT, Li XH, Yu J, McLaughlin J, Cheng D, Mathis C, Moreno BH, Woods K, Knights AJ, Garcia-Diaz A, Wong S, Hu-Lieskovan S, Puig-Saus C, Cebon J, Ribas A, Yang L, Witte ON, Baltimore D (Oct 2018). Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules. Proc Natl Acad Sci U S A.
Ott P, Govindan R, Niang A, Friedlander T, Margolin K, Lin J, Bhardwaj N, Hellmann M, Srinivasan L, Greshock J, Moles M, Gaynor R, Goldstein M, Hu-Lieskovan S (October 2018). A Personal Neoantigen Vaccine, NEO-PV-01, with anti-PD1 Induces Broad De Novo Anti-Tumor Immunity in Patients with Metastatic Melanoma, NSCLC, and Bladder Cancer [Abstract]. 29(Supplement 8), viii400-viii441.
Hamid O, Hu-Lieskovan S, Ros W, Diab A, El-Khoueiry A, Thompson J, Eskens F, X Doi T, Wasser J, Spano J, Angevin E, Rizvi N, Wasser J, Ott P, Chiappori A, Joh T, Krupka H, Potluri S, Wang X, Ganguly B, Chou J, Doi T (October 2018). Pharmacodynamic (PD) changes in tumors and peripheral blood T cell receptor (TCR) repertoire in a phase I study combining OX40 (PF-04518600) and 4-1BB (utomilumab) agonistic monoclonal antibodies (mAbs) [Abstract]. 29(Supplement 8), viii400-viii441.
Gaffney DK, Hasibe M, Kepka D, Maurer KA, Werner TL (2018). Too many women are dying from cervix cancer: Problems and solutions. Gynecol Oncol.
A NecchiD Pouessel, R Leibowitz-Amit, A Flechon, S Gupta, P Barthelemy, M Maio, X Zhu, E Asatiani, G Serbest, H Zhen, Y Loriot (10/01/2018). Interim results of fight-201, a phase II, open-label, multicenter study of INCB054828 in patients (pts) with metastatic or surgically unresectable urothelial carcinoma (UC) harboring fibroblast growth factor (FGF)/FGF receptor (FGFR) genetic alterations (GA). [Abstract]. ESMO Annual Meeting 2018.
Patel SB, Akerley WL, Ose D, Haydell T, Martineau J, Dunson WA, Chalmers AW, Cannon L, Meropol NJ, Haaland B (2018). Prognostic value of patient-reported outcomes (PROs) in advanced cancer [Abstract]. Journal of Clinical Oncology, 36.
McPherson JP, Patel SB, Igumnova E, Pettit J, Ose D, Haydell T, Martineau J, Meropol NJ, Beck AC (2018). Real-time assessment of resource utilization and subsequent cost analysis in cancer patients (pts) near the end of life (EOL) [Abstract]. Journal of Clinical Oncology, 36.
Necchi A, Pond GR, Moschini M, Plimack ER, Niegisch G, Yu EY, Bamias A, Agarwal N, Vaishampayan U, Theodore C, Sridhar SS, Rosenberg JE, Bellmunt J, Gallina A, Colombo R, Montorsi F, Briganti A, Galsky MD (2018). Development of a Prediction Tool for Exclusive Locoregional Recurrence After Radical Cystectomy in Patients With Muscle-Invasive Bladder Cancer. PMID: 30292628 [Abstract]. Clinical Genitourinary Cancer.
Tripathi A, Agarwal N (2018). Editorial Comment. PMID: 30189185 [Abstract]. The Journal of Urology.
Kingsford R, Pitt D, Low S, Weaver L, Moehle J, Cohen Al, Werner TL (2018). How to Be a Principal Investigator: Developing and Implementing of a Practical Training Program [Abstract]. 10th Annual AACI CRI Meeting Abstract Template.
Schrijver LH, Olsson H, Phillips KA, Terry MB, Goldgar DE, Kast K, Engel C, Mooij TM, Adlard J, Barrowdale D, Davidson R, Eeles R, Ellis S, Evans DG, Frost D, Izatt L, Porteous ME, Side LE, Walker L, Berthet P, Bonadona V, Leroux D, Mouret-Fourme E, Venat-Bouvet L, Buys SS, Southey MC, John EM, Chung WK, Daly MB, Bane A, van Asperen CJ, Gomez Garcia EB, Mourits MJE, Roos-Blom MJ, Friedlander ML, McLachlan SA, Singer CF, Foretova L, Gerdes AM, Caldes T, Olah E, Jakubowska A, Nogues C, Andrieu N, Easton DF, van Leeuwen FE, Hopper JL, Milne RL, Antoniou AC, Rookus MA, on behalf of EMBRACE, GENEPSO, BCFR, HEBON, kConFab, and IBCCS (2018). Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study. doi: 10.1093/jncics/pky023. JNCI Cancer Spectrum, 2(3).
Diab A, Hamid O, Thompson J, Schellens J, Eskens F, Doi T, Hu-Lieskovan S, Long H Joh T, Potluri S, Wang X, Fleener C, Taylor C, Ganguly B, Chou J, El-Khoueiry A (July 2018). Pharmacodynamic changes in tumor RNA expression and the peripheral blood T cell receptor (TCR) repertoire in a Phase I study of OX40 agonistic monoclonal antibody (mAb) PF-04518600 (PF-8600 [Abstract]. 78(13 Supplement), Abstract CT010.
Nowicki T, Berent-Maoz B, Huang R, Wang X, Cheung-Lau G, Kaplan-Lefko P, Cabrera P, Tran J, Carretero I, Grasso C, Hu-Lieskovan S, Chmielowski B, Comin-Anduix B, Singh A, Ribas A (July 2018). A pilot trial of the combination of transgenic NY-ESO-1-reactive adoptive cellular therapy with dendritic cell vaccination with or without ipilimumab in patients with sarcoma and melanoma [Abstract]. 78(13 Supplement), CT008.
Abril-Rodriguez G, Grasso C, Zaretsky J, Berent-Maoz B, Hu-Lieskovan S, Ribas A (July 2018). Role of PAK4 in cancer immune cell exclusion [Abstract]. 78(13 Supplement), Abstract 4755.
Parisi G, Saco J, Bergara F, Krstofinski P, Zhang R, Saus C, Hu-LIeskovan S, Comin-Anduix B, Wu A, Charych D, Ribas A (July 2018). Enhanced expansion and tumor targeting of adoptively transferred T cells with NKTR-214 [Abstract]. 78(13 Supplement), Abstract 3566.
Ott P, Ramaswamy G, Naing A, Friedlander T, Margolin K, Lin J, Bhardwaj N, Hellmann M, Srinivasan L, Greshock J, Moles M, Gaynor R, Goldstein M, Hu-Lieskovan S (July 2018). A personal neoantigen vaccine, NEO-PV-01, with anti-PD1 induces broad de novo anti-tumor immunity in patients with metastatic melanoma, NSCLC, and bladder cancer [Abstract]. 89(13 Supplement), Abstract CT125.
Evans E, Bussler H, Mallow C, Reilly C, Torno S, Scrivens M, Howell A, Balch L, Leonard J, Fisher T, Allen C, Clavijo P, Lesinski G, Wu C, Hu-Lieskovan S, Ribas A, Greengard E, Smith E, Zauderer M (July 2018). Shifting the tumor microenvironment with first-in-class Semaphorin 4D mab for combination immunotherapy [Abstract]. 78(13 Supplement), Abstract 1762.
Kugel CH 3rd, Douglass SM, Webster MR, Kaur A, Liu Q, Yin X, Weiss SA, Darvishian F, Al-Rohil RN, Ndoye A, Behera R, Alicea GM, Ecker BL, Fane M, Allegrezza MJ, Svoronos N, Kumar V, Wang DY, Somasundaram R, Hu-Lieskovan S, Ozgun A, Herlyn M, Conejo-Garcia JR, Gabrilovich D, Stone EL, Nowicki TS, Sosman J, Rai R, Carlino MS, Long GV, Marais R, Ribas A, Eroglu Z, Davies MA, Schilling B, Schadendorf D, Xu W, Amaravadi RK, Menzies AM, McQuade JL, Johnson DB, Osman I, Weeraratna AT (Jun 2018). Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations. . Clin Cancer Res.
Yousef Zakharia, Olivier Rixe, John Harris Ward, Joseph J Drabick, Montaser F Shaheen, Mohammed M Milhem, David Munn, Eugene Paul Kennedy, Nicholas N Vahanian, Charles J Link, Robert R McWilliams, University of Iowa Hospitals and Clinics, Holden Comprehensive Cancer Center, Iowa City, IA, GRU Cancer Center, Augusta, GA, Huntsman Cancer Inst Univ of Utah, Salt Lake City, UT, Penn State Hershey Medical Center, Hershey, PA, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, Georgia Cancer Center, Augusta University, Augusta, GA, NewLink Genetics Corporation, Ames, IA, Mayo Clinic, Rochester, MN (06/04/2018). Phase 2 trial of the IDO pathway inhibitor indoximod plus checkpoint inhibition for the treatment of patients with advanced melanoma.Presented at 2018 ASCO Annual meeting June 4, 2018. [Abstract]. J Clin Oncology, 36(suppl. abstr 9512).
Petros Grivas, Gregory Russell Pond, Rebecca J Nagy, Pedro C Barata, Prateek Mendiratta, Dharmesh Gopalakrishnan, Alexandra Drakaki, Sumati Gupta, Neeraj Agarwal, Jue Wang, Bishoy Faltas, Ulka N Vaishampayan, Gurudatta Naik, Bradley Alexander McGregor, Sumanta K Pal, Lesli Ann Kiedrowski, Richard B Lanman, Guru Sonpavde (06/01/2018). Association of circulating tumor (ct)-DNA genomic alterations (GA) with outcomes in metastatic urothelial carcinoma (mUC). ASCO Annual Meeting 2018 [Abstract].
Pant S, Spira AI, Cho SBC, Goel S, Hoimes CJ, Alva AS, Balaraman R, Bauer TM, Lowry PA, Ramaekers RC, Siegel RD, Werner TL, Tannir NM, Faltaos D, Potvin D, Neuteboom ST, Christensen J, Chao RC, Kyriakopoulos C (2018). Evalution of the spectrum selective RTK inhibitor sitravatinib in clear cell renal cell carcinoma (ccRCC) refractory to anti-angiogenic therapy (AAT) [Abstract]. J Clin Oncol, 36.
Hu-Lieskovan S, Torrejon D, Zaretsky J, Tsoi J, Cheung-Lau G, Vega-Crespo A, Meeth K, Prins R, Graeber T, Besenberg M, Grasso C, Comin-Anduix B, Rbias A (June 2018). Reversing resistance to PD-1 blockade by combination of talimogene laherparepvec (T-VEC) with pembrolizumab (pembro) in advanced melanoma patients following progression on a prior PD-1 inhibitor: SWOG S1607 (NCT#02965716) [Abstract]. 36(15 Supplement), TPS9603.
Vandersalde A, Latkovic-Taber M, Hu-Lieskovan S, Grossmann K, Sosman J, Campos D, Wu M, Ribas A36 (June 2018). Combining ipilimumab (ipi) and nivolumab (nivo) in advanced melanoma following progression on a PD-1 inhibitor (SWOG S1616) [Abstract]. 36(15 Supplement), TPS9597.
Kendra K, Moon J, Hu-Lieskovan S, Carson III W, Campos D, Cochran A, Wu M, Ribas A (June 2018). SWOG S1512: A phase II and pilot trial of Pembrolizumab in patients with resectable or unresectable desmoplastic melanoma (DM) [Abstract]. 36(15 Supplement), TPS9608.
Hu-Lieskovan S, Torrejon D, Zaretsky J, Tsoi J, Cheung-Lau G, Vega-Crespo A, Meeth K, Prins R, Graeber T, Besenberg M, Grasso C, Comin-Anduix B, Rbias A (June 2018). CD4 cells are essential in the complete anti-tumor response to PD1 blockade in a syngeneic murine melanoma model with activated WNT signaling [Abstract]. 36(15 Supplement), 12013.
Lu H, Cummings A, Goldman J, Lisberg A, Hu-Lieskovan S, Grogan T, Gukasyan J, Madrigal J, Carroll J, Bornazyan K, Jones B, Noor Z, Zaretsky J, Elashoff D, Slamon D, Dubinett S, Garon E (June 2018). Human leukocyte antigen (HLA) B44 supertype and immunotherapy outcomes in non-small cell lung cancer (NSCLC) [Abstract]. 36(15 Supplement), Abstract 3025.
Bahary N, Wang-Gillam A, Haraldsdottir S, Somer BG, Lee JS, ORourke MA, Nayak-Kapoor A, Beatty GL, Liu M, Delman D, Rossi GR, Kennedy EP, Vahanian NN, Link CJ, Garrido-Laguna I (2018 ASCO Annual Meeting). Phase 2 trial of the IDO pathway inhibitor indoximod plus gemcitabine / nab-paclitaxel for the treatment of patients with metastatic pancreas cancer. [Abstract]. J Clin Oncol 36, 2018 (suppl; abstr 4015).
Boothe D, Clyde JW, Christensen M, Patel SB, Lloyd S (2018). A comprehensive analysis of clinical trials including both immunotherapy and radiation therapy. J Radiat Oncol, 7(3), 223-232.
Boothe D, Clyde JW, Christensen M, Patel SB, Lloyd S (2018). A comprehensive analysis of clinical trials including both immunotherapy and radiation therapy [Abstract]. (7), 223–232.
Bailey EB, Merriman J, Maughan B, Poole A, Tantravahi SK, Agarwal AM, Batten JA, Patel SB, Pal Sumanta K, Stenehjem DD, Agarwal N (2018). Effect of treatment dose reductions in the setting of hand-foot syndrome on survival outcomes in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor receptor inhibitors. J Oncol Pharm Pract, 3, 190-197.
Park J, Blackburn BE, Rowe K, Snyder J, Wan Y, Deshmukh V, Newman M, Fraser A, Smith K, Herget K, Burt L, Werner TL, Gaffney DK, Lopez A, Mooney A (2018). Rural-metropolitan disparities in ovarian cancer survival: A statewide population-based study. Ann Epidemiol.
Brady SW, McQuerry JA, Qiao Y, Piccolo SR, Shrestha G, Jenkins DF, Layer RM, Pedersen BS, Miller RH, Esch A, Selitsky SR, Parker JS, Anderson LA, Dalley BK, Factor RE, Reddy CB, Boltax JP, Li DY, Moos PJ, Gray JW, Heiser LM, Buys SS, Cohen AL, Johnson WE, Quinlan AR, Marth G, Werner TL, Bild AH (2018). Publisher Correction: Combating subclonal evolution of resistant cancer phenotypes. Nat Commun, 8(1), 1231.
Sumati Gupta, Andrew Butterfield, Timothy Parnell, Alexis Weston, Mohan Kaadige, Sunil Sharma (2018). Reversible LSD1 (KDM1A) inhibition with HCI2509 is growth inhibitory in bladder cancer cell lines and causes gene expression changes that reveal rational therapeutic partners [Abstract]. Presented at Targeting DNA Methylation and Chromatin for Cancer Therapy in Atlanta March 2018.
Jacob Adashek, Sumanta K Pal, Vincent M Chung, Scott T Tagawa, Joel Picus, Hani M Babiker, Sumati Gupta, Raymond Couric Wadlow, Julie Poore, Christine Peterson, Ely Benaim (2018). Preliminary results from an ongoing phase 2a study of RX-3117, an oral nucleoside analogue to treat advanced urothelial cancer (aUC). ASCO Annual Meeting 2018 [Abstract].
Pishvaian MJ, Rolfo CD, Liu SV, Multani PS, Maneval EC, Garrido-Laguna I (January 2018). Clinical benefit of entrectinib for patients with metastatic pancreatic cancer who harbor NTRK and ROS1 fusions. [Abstract]. J Clin Oncol 36, 2018 (suppl 4S., abstr 521).
Bendell JC, Pelzer U, Womack MS, Borazanci EH, Bahary N, Garrido-Laguna I, Maur M, Prater T, Levy DE, Cronier D, Ramage S, Macarulla T, Cannon S (January 2018). A phase 1b (open-label)/phase 2 (randomized, double-blinded) study evaluating nab-paclitaxel and gemcitabine with or without olaratumab in first-line treatment of metastatic pancreatic cancer. [Abstract]. J Clin Oncol 36, 2018 (suppl 4S; abstr TPS524).
Eroglu Z Zaretsky J Hu-Lieskovan S Kim DW, Algazi A, Johnson D, Liniker E, Kong B, Munhoz R, Rapisuwon S, Chmielowski B, Homet Moreno B, Cherry G, Berent-Maoz B, Comin-Anduix B, Wang X, Tumeh PC, Shintaku IP, Hugo W, Lo RS, Sosman JA, Joseph R, Postow M, Hwu W-J, Messina J, Long G, Ribas A Equal contribution as first authors, Corresponding authors (Jan 2018). High response to PD-1 blockadein desmoplastic melanoma. Nature, 553(7688), 347-350.
Nevala-Plagemann CD, Francis S, Cavalieri CC, LLoyd S, Garrido-Laguna I (January 2018). The effect of adjuvant chemotherapy in patients without local nodal metastases following neoadjuvant chemoradiotherapy and esophagectomy for locally advanced esophageal cancer. [Abstract]. J Clin Oncol 36, 2018 (suppl 4S; abstr 111).
Francis S, Nevala-Plagemann CD, Cavalieri CC, Lloyd S, Garrido-Laguna I (January 2018). Postoperative chemotherapy in patients who are pN+ following neoadjuvant chemoradiation for locally advanced esophageal cancer. [Abstract]. J Clin Oncol 36, 2018 (suppl 4S, abstr 97).
Swami U, Monga V, Knutson T, Bossler A, Zakharia Y, Milhem M (2018). Prognostic markers for progression free survival (PFS) to anti PD-1 therapies in metastatic melanoma [Abstract]. J Clin Oncol, 36(suppl; abstr e21527).
Dang C, Ewer MS, Delaloge S, Ferrero JM, Verrill M, Colomer R, Vieira C, de la Cruz Merino L, Lucas J, Werner TL, Douthwaite H, Bradley D, Waldron-Lynch M, Eng-Wong J, Swain SM (2017). Safety of adjuvant treatment with pertuzumab plus trastuzumab after neoadjuvant anthracycline-based chemotherapy in patients with HER2-positive localized breast cancer: Updated results from the BERENICE study. 2017 San Antonio Breast Cancer Symposium.
Evans E, Bussler H, Mallow C, Reilly C, Torno S, Scrivens M, Foster C, Howell A, Balch L, Leonard J, Fisher T, Jenkins D, Allen C, Clavijo P, Hu-Lieskovan S, Ribas A, Smith E, Zauderer M (November 2017). Targeting the tumor microenvironment with first-in-class Semaphorin4D MAb for combination immunotherapy. [Abstract]. 5(87), Abstract P268.
Reynolds KL, Bedard PL, Lee SH, Lin CC, Tabernero J, Alsina M, Cohen E, Baselga J, Blumenschein G Jr, Graham DM, Garrido-Laguna I, Juric D, Sharma S, Salgia R, Seroutou A, Tian X, Fernandez R, Morozov A, Sheng Q, Ramkumar T, Zubel A, Bang YJ (2017). A Phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer. BMC Cancer, Sep 12; 17(1), 646.
Hamid O, Ros W, Thomson J, Hu-Lieskovan S, Eskens F, Diab A, Doi T, Wasser J, Spano J, Rizvi N, Angevin E, Chiappori A, Ott P, Ganguly B, Fleener C, Dell V, Liao K, Tenshang J, Chou J, El-Khoueiry A (September 2017). Safety, Pharmacokinetics and Pharmacodynamics Data from a Phase I Dose-Escalation Study of OX40 Agonistic Monoclonal Antibody (mAb) PF-04518600 in Combination with Utomilumab, A 4-1BB Agonistic mAb [Abstract]. 28(5 Supplement), v403-v427.
Hu-Lieskovan S, Braiteh F, Grilley-Olson J, Chou J, Davda J, Jin B, Forgie A, Rassam D, Youssef S, Johnson M (September 2017). Safety, Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of PF‑06801591, an anti-PD1 antibody administered intravenously (IV) or subcutaneously (SC) [Abstract]. 28(5 Supplement), v403-v427.
Ott P, Naing A, Ramaswamy G, Margolin K, Moles M, Gaynor R, Goldstein M, Hu-Lieskovan S (September 2017). An open-label, Phase IB study of NEO-PV-01 + Adjuvant with Nivolumab in Patients with Melanoma, Non-Small Cell Lung Carcinoma, or Transitional Cell Carcinoma of the Bladder. [Abstract]. 28(5 Supplement), v403-v427.
Ahmad Halwani, Zachary Burningham, Kelli M Rasmussen, Vikas Patil, Sujata Narayanan, Shih-Wen Lin, Susheela Carroll, Ling-I Hsu, Julie Graff, Robert Dreicer, Sumati Gupta, Clarke Low, Brian C Sauer (2017). Practice Patterns in Metastatic Castration-Resistant Prostate Cancer (mCRPC): Evidence From the Veterans Health Administration [Abstract]. ESMO Annual Meeting 2017.
Sumanta Pal, Vincent Chun, Scott Tagawa, Joel Picus, Sumati Gupta, Julie Poore, Christine Peterson and Ely Benaim (2017). RX-3117, an Oral Hypomethylating Agent to Treat Advanced Solid Tumors (ST): Interim results from an Ongoing Phase 2a Study in Metastatic Bladder Cancer [Abstract]. ESMO Annual Meeting 2017.
Poole A, Gill D, Hahn AW, Johnson E, Carroll E, Boucher K, Nussenzveig R, Maughan B, Agarwal N (2017). Incidence and Characterization of Antiandrogen Withdrawal Syndrome After Discontinuation of Treatment With Enzalutamide in Castration-resistant Prostate Cancer. Clin Genitourin Cancer, S1558-7673(10.1016/j.).
Parisi G, Saco J, Hu-Lieskovan S, Zhang R, Krystofinski P, Puig Saus C, Charych D, Ribas A (July 2017). Antitumor activity of NKTR-214 in combination with pmel-1 ACT in an aggressive murine melanoma model [Abstract]. 77(13 Supplement), Abstract 2671.
Zaretsky J, Garcia-Diaz A, Shin D, Escuin-Ordinas H, Hugo W, Hu-Lieskovan S, Eroglu Z, Torrejon D, Tumeh P, Lo R, Ribas A (July 2017). Mechanisms of resistance to anti-PD-1 immunotherapy through interferon pathway mutations [Abstract]. 77(13 Supplement), Abstract NG04.
Torrejon D, Zaretsky J, Shin D, Onyshchenko M, Abril-Rodriguez G, Vega-Crespo A, Puig-Saus C, Cheung-Lau G, Long C, Comin-Anduix B, Hu-Lieskovan S, Ribas A (July 2017). Interrogating resistance mechanisms to PD-1 blockade therapy with CRISPR [Abstract]. 35(15 Supplement), Abstract 3077.
Naing A, HuLieskovan S, Govindan R, Margolin K, Moles M, Gaynor R, Goldstein M, Ott P (July 2017). An open‐label, Phase IB study of NEO‐PV‐01 + Adjuvant with Nivolumab in Patients with Melanoma, Non‐Small Cell Lung Carcinoma, or Transitional Cell Carcinoma of the Bladder [Abstract]. 35(15 Supplement), Abstract TPS3116.
Hu-Lieskovan S, Eroglu Z, Zaretsky J, Kim D, Algazi A, Johnson D, Liniker E, Kong B, Munhoz R, Rapisuwon S, Chmielowski B, Sosman J, Scolyer R, Joseph R, Postow M, Carlina M, Hwu W-J, Long G, Ribas A (July 2017). Analysis of mutational burden and adaptive immune response in desmoplastic melanomas treated with PD-1/L1 inhibitors [Abstract]. 35(15 Supplement), Abstract 9558.
Evans E, Bussler H, Mallow C, Reilly C, Torno S, Scrivens M, Foster C, Howell A, Comeau S, Balch L, Knapp A, Leonard J, Fisher T, Hu-Lieskovan S, Ribas A, Smith E, Zauderer M (July 2017). Breaking down the barrier restricting infiltration and differentiation of APC in the tumor microenvironment with a first-in-class antibody targeting Semaphorin4D, and rational combination therapies [Abstract]. 77(13 Supplement), Abstract 3661.
Tolcher A, Sznol M, Hu-Lieskovan S, Papadopoulos KP, Patnaik A, Rasco DW, Di Gravio D, Huang B, Gambhire D, Chen Y, Thall AD, Pathan N, Schmidt EV, Chow LQ (Jun 2017). Phase Ib study of utomilumab (PF-05082566), a 4-1BB/CD137 agonist, in combination with pembrolizumab in patients with advanced solid tumors. Clin Cancer Res.
Garrido-Laguna I, Krop IE, Burris H, Hamilton EP, Braiteh FS, Weise A, Abu-Khalaf MM, Zopf C, Lakshminarayanan M, Holland JS, Baffa R, Hong DS (2017). A phase I study of PF-06647263, a novel EFNA4-ADC, in patients with metastatic triple negative breast cancer. Presented at the 2017 ASCO Annual Meeting on June 5, 2017. [Abstract]. J Clin Oncol, 35(suppl; abstr 2511).
El-Khoueiry A, Hamid O, Thompson JA, Ros W, Eskens FA, Doi T, Hu-Lieskovan S, Chou J, Liao K, Ganguly BJ, Fleener CA, Joh T, Diab A (2017). The Relationship of Pharmacodynamics (PD) and Pharmacokinetics (PK) to Clinical Outcomes in a Phase I Study of OX40 Agonistic Monoclonal Antibody (mAb) PF-04518600 (PF-8600) [Abstract]. 35(15 Supplement), Abstract 3027.
Trang H Au, Kai Wang, David Stenehjem, Ignacio Garrido-Laguna (2017). Personalized and precision medicine: integrating genomics into treatment decisions in gastrointestinal malignancies. J Gastrointest Oncol, 8(3), 387-404.
Pandha HS, Ralph C, Harrington K, Curti BD, Sanborn RE, Akerley WL, Gupta S, Rudin CM, Rosenberg JE, Kaufman DR, Schmidt EV, Grose M, Shafren D (2017). Keynote-200 phase 1b: A novel combination study of intravenously delivered coxsackievirus A21 and pembrolizumab in advanced cancer patients [Abstract]. ASCO Annual Meeting 2017.
Grivas P, Nagy RJ, Pond GR, Gupta S, Wang J, Vaishampayan UN, Pal SK, Bilen MA, Naik G, Ghatalia P, Hoimes CJ, Gopalakrishnan D, Barata P, Lanman RB, Talasaz AA, Sonpavde G (2017). Circulating tumor (ct)-DNA alterations in urothelial/bladder cancer (UC/BC): Updates on a dynamic genomic landscape [Abstract]. ASCO Annual Meeting 2017.
Choueiri TK, Larkin JMG, Oya M, Thistlethwaite FC, Martignoni M, Nathan PD, Powles T, McDermott DF, Robbins PB, Chism DD, Cho DC, Atkins MB, Gordon MS, Gupta S, Uemura H, Tomita Y, Compagnoni A, di Pietro A, Rini BI (2017). First-line avelumab + axitinib therapy in patients (pts) with advanced renal cell carcinoma (aRCC): Results from a phase Ib trial. [Abstract]. ASCO Annual Meeting 2017.
Gong J, Chung VM, Picus J, Tagawa ST, Gupta S, Poore J, Peterson C, Benaim E, Pal SK (2017). Activity of RX-3117, an oral antimetabolite nucleoside, in subjects with metastatic bladder cancer resistant to gemcitabine: Preliminary results of a phase Ia/IIb study. [Abstract]. ASCO Annual Meeting 2017.
Swami U, Monga V, Tanas M, Bossler A, Mott S, Smith B, Milhem M (2017). A pilot study targeting angiogenesis using bevacizumab combined with gemcitabine/docetaxel and valproic acid (VPA), a histone deacetylase inhibitor (HDACi) in advanced soft tissue sarcomas (STS) [poster presentation also given at the American Association for Cancer Research Special Conference on Advances in Sarcomas: From Basic Science to Clinical Translation, Philadelphia, PA, May, 18, 2017 [Abstract]. Clinical Cancer Research, 24(2 suppl), B23.
Michaelson MD, Gupta S, Agarwal N, Szmulewitz RZ, Powles T, Pili R, Bruce JY, Vaishampayan UN, Larkin JMG, Rosbrook B, Lechuga M, Valota O, Tarazi JC, Shepard DR (2017). Axitinib plus crizotinib in patients with advanced solid tumors and metastatic renal cell carcinoma (mRCC): Preliminary phase 1b results [Abstract]. Journal of Clinical Oncology.
De Bono JS, Hussain M, Thiery-Vuillemin A, Mateo J, Sartor AO, Chi KN, Fizazi K, Twardowski P, Agarwal N, Sandhu SK, Olmos D, Shore ND, Saad F, Liu S, Goessl CD, Burgents J (2017). PROfound: A randomized Phase III trial evaluating olaparib in patients with metastatic castration-resistant prostate cancer and a deleterious homologous recombination DNA repair aberration [Abstract]. Journal of Clinical Oncology.
Harshman LC, Werner L, Tripathi A, Wang X, Maughan BL, Antonarakis ES, Nakabayashi M, McKay R, Pomerantz M, Mucci LA, Taplin ME, Sweeney CJ, Lee GM, Kantoff PW (2017). The impact of statin use on the efficacy of abiraterone acetate in patients with castration-resistant prostate cancer. Prostate, 77(13)(10.1002/pr), 1303-1311.
Cohen AL, Neumayer L, Boucher K, Factor R, Shtrestha G, Wade M, Lamb G, Arbogast Ky, Piccolo S, Riegert J, Schabel M, Bild A, Werner TL (4/2017). A Window of Opportunity Study of Valproic Acid in Breast Cancer Testing a Gene Expression Biomarker [Abstract]. JCO Precision Oncology, 1(April 2017), 1-11.
Tao R, Lloyd S, Burt L, Whisenant J, Garrido-Laguna I, Das P (2017). Pelvic Reirradiation for the Treatment of Locally Recurrent Rectal Cancer. Current Colorectal Cancer Reports, 13(2), 175-82.
Ahmad Halwani, Kelli M Rasmussen, Vikas Patil, Zachary Burningham, Sujata Narayanan, Shih-Wen Lin, Susheela Carroll, Ling-I Hsu, Julie N Graff, Robert Dreicer, Sumati Gupta, Clarke Low, Brian C, Saier (2017). Racial Disparities in Metastatic Castrate-Resistant Prostate Cancer (mCRPC): Evidence from the Veteran’s Health Administration (VHA) AACR [Abstract]. Prostate Cancer: Advances in Basic, Translational, and Clinical Research meeting 2017.
Kelli M Rasmussen, Vikas Patil, Zachary Burningham, Sujata Narayanan, Shih-Wen Lin, Susheela Carroll, Ling-I Hsu, Julie Graff, Robert Dreicer, Sumati Gupta, Clarke Low, Brian C Sauer, Ahmad Halwani (2017). The role of academic affiliation in the treatment of metastatic castrate-resistant prostate cancer in the Veterans Health Administration Abstract- AVAHO 2017 [Abstract]. AVAHO 2017.
Gill DM, Stenehjem DD, Cheng HH, Kessler ER, Hahn AW, Gupta S, Alex A, Patel S, Chittoria N, Twardowski P, Vaishampayan UN, Agarwal N (2017). Association of time from definitive therapy (DT) to start of androgen deprivation therapy (ADT) for metastatic disease and survival outcomes in men with new metastatic hormone-sensitive prostate cancer (mHSPC) [Abstract]. Journal of Clinical Oncology, 35(6S suppl), abstract 265.
Poole A, Gill DM, Hahn AW, Johnson E, Carroll E, Batten JA, Gupta S, Boucher KM, Maughan BL, Agarwal N (2017). Incidence and characterization of antiandrogen withdrawal syndrome (AAWS) after enzalutamide (ENZA) in patients (pts) with metastatic castration-refractory prostate cancer (mCRPC). [Abstract]. GU ASCO 2017.
Hahn AW, Gill DM, Streeter J, Bailey EB, Carroll E, Aryal L, Batten JA, Gupta S, Agarwal N, Maughan BL (2017). Intra-individual genomic diversity between circulating tumor cell-free DNA (cfDNA) and tumor tissue testing in metastatic renal cell carcinoma (mRCC) [Abstract]. GU ASCO 2017.
Gupta S, Albertson DJ, Parnell T, Dalley B, O Shea J, Weston A, Butterfield A, Pappas LM, Schiffman JD, Sharma S, Agarwal N (2017). Clinical and translational investigation of pan-HDAC inhibition in advanced urothelial carcinoma (UC) [Abstract]. GU ASCO 2017.
Gupta S, Albertson DJ, Gaston D, Heilbrun ME, Agarwal N, Liu T, Miller VA, Ross JS, Milis SZ, Ali SM (2017). Comprehensive genomic sequencing of urothelial tumors to identify rare driver genomic alterations in SMARCB1 in a subset of patients [Abstract]. GU ASCO 2017.
Carroll E, Gill DM, Poole A, Hahn AW, Bailey EB, Streeter J, Batten JA, Gupta S, Agarwal N, Maughan BL (2017). Genomic diversity between primary tumor tissue and tumor circulating cell-free DNA (cfDNA) in patients (pts) with metastatic prostate cancer [Abstract]. GU ASCO 2017.
Grivas P, Nagy RJ, Pond GR, Gupta S, Wang J, Vaishampayan UN, Pal SK, Bilen MA, Naik G, Ghatalia P, Gopalakrishnan D, Barata P, Lanman RB, Talasaz AA, Sonpavde G (2017). Circulating tumor (ct)-DNA alterations in advanced urothelial carcinoma: Association with outcomes and evolution with therapy. [Abstract]. GU ASCO 2017.
Gill DM, Stenehjem DD, Cheng HH, Kessler ER, Hahn, AW, Gupta S, Alex A, Patel SB, Chittoria N, Twardowski P, Vaishampayan UN, Agarwal N (2017). Association of time from definitive therapy (DT) to start of androgen deprivation therapy (ADT) for metastatic disease and survival outcomes in men with new metastatic hormone-sensitive prostate cancer (mHSPC) [Abstract]. GU ASCO 2017.
Sharma P, Hu-Lieskovan S, Wargo J, Ribas A (February 2017). Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy. [Review]. Cell, 168(4), 707-723.
Patel S, Mason CC, Glenn MJ, Paxton CN, South ST, Cessna MH, Asch J, Cobain EF, Bixby DL, Smith LB, Reshmi S, Gastier-Foster JM, Schiffman JD, Miles RR (2017). Genomic analysis of adult B-ALL identifies potential markers of shorter survival. Leuk Res, 56, 44-51.
Pendurti G, Shah U, Swami U, Hou Y, Ghalib MH, Chaudhary I, Polineni R, Klobocista M, Mukherjee P, Chuy JW, Kaubisch A, Rajdev L, Aparo S, Goel S (2017). Developing a novel prognostic model to predict overall survival (OS) and 90 day mortality rate (90DM) for metastatic colorectal cancer (mCRC) patients in phase I trials [Abstract].
Goel S, Moran T, Coronado C, Ramirez SV, Chaudhary I, Ghalib MH, Swami U, Hou Y, Carcereny E, Alcantara J, Dios JLI, Miguel BD, Buges C, Rosell R (2017). Phase I dose-finding and pharmacokinetic study of a combination of elisidepsin (E) and erlotinib (T) in patients (pts) with advanced solid tumors [Abstract].
Carmicheal H, Matsen C, Freer P, Kohlmann W, Stein M, Buys SS, Colonna S, MD (2017). Breast cancer screening of pregnant and breastfeeding women with BRCA mutations. doi: 10.1007/s10549-017-4122-y. Review. PubMed PMID: 28138892. Breast Cancer Res Treat, 162(2), 225-230.
Shah U, Pendurti G, Swami U, Hou Y, Ghalib MH, Chaudhary I, Mani S, Goel S, Aparo S (2017). Clinical outcome for patients with metastatic colorectal cancer (mCRC) enrolled in phase I clinical trials: Single institution experience [Abstract].
Cavalieri CC, Swanson E, Whisenant JR, Weis JR, Gilcrease GW, Stenehjem DD, Sharma S, Garrido-Laguna I (Jan 2017). Pembroliuzmab in gastrointestinal (GI) malignancies with defective DNA mismatch repair (dMMR): A single institution experience. Presented at the 2017 Gastrointestinal Cancers Symposium, Poster Session C: Cancers of the Colon, Rectum, and Anus. [Abstract]. J Clin Oncology, 35(suppl 4S; abstract 792).
Theresa Louise Werner, Esther Kannapel, Melissa Chen, Judy Chen, Adam Louis Cohen (2017). Safety and PK results from a phase Ib study of AL3818 (anlotinib) hydrochloride in subjects with ovarian, cervical, and endometrial cancer [Abstract]. 35(15).
Kuzman JA, Stenehjem DD, Merriman J, Agarwal AM, Patel SB, Hahn AW, Alex A, Albertson D, Gill DM, Agarwal N (2017). Neutrophil-lymphocyte ratio as a predictive biomarker for response to high does interleukin-2 in patients with renal cell carcinoma. BMC Urology.
Hu-Lieskovan S, Ribas R (Jan/Feb 2017). New combination strategies using PD-1/ L1 checkpoint inhibitors as a backbone. [Review]. Cancer J, 23(1), 10-22.
Maughan BL, Bailey E, Gill DM, Agarwal N (2017). Incidence of Immune-Related Adverse Events with Program Death Receptor-1-and Program Death Receptor-1 Ligand-Directed Therapies in Genitourinary Cancers. Front Oncol, 7, 56.
Hu-Lieskovan S, Chmielowski B, Ribas A (2017). Cancer Immunotherapy. In Chmielowski B, Territo MC (Eds.), Manual of Clinical Oncology (Eighth Edition). Lippincott Williams & Wilkins.
Odei B, Boothe D, Suneja G, Werner TL, Gaffney DK (2017). Chemoradiation Versus Chemotherapy in Uterine Carcinosarcoma: Patterns of Care and Impact on Overall Survival [Epub ahead of Print]. Am J Clin Oncol.
Thibault J, Patel SB (2017). A Case of Mytomycin-C Induced Pulmonary Veno-Occlusive Disease [Abstract]. AVAHO Updates.
Kam AE, Chaudhary I, Ghalib MH, Shah UH, Swami U, Kuo DYS, Hwang C, Elrafei TN, Cohen B, Gartrell BA, Kaledzi E, Chuy JW, Cheng H, Rajdev L, Haigentz M Jr, Mani S, Goel S (2017). Risks and benefits of phase I trials: Eighteen-year experience from a single institution [Abstract]. J Clin Oncol, 35(suppl; abstr e18146).
Swami U, Monga V, Zakhraia Y, Milhem M (2017). Immunomodulation of pembrolizumab (pembro) treated metastatic melanoma patients (pts) after progression with sequential temozolomide (TMZ): A case series [Abstract]. J Clin Oncol, 35(suppl 7S; abstract 123).
Colonna SV, Gammon A (2016). Management of the Patient with a Genetic Predisposition for Breast Cancer. In Dr. Ismail Jatoi and Dr. Achim Rody (Eds.), Management of Breast Diseases (Second Edition).
Ribas A, Hu-Lieskovan S (November 2016). What does PD-L1 positive or negative tumors mean? Perspective for Clinical Correlates of Immunotherapy. [Review]. J Exp Med, 213(13), 2835-2840.
Shin DS, Zaretsky JM, Escuin-Ordinas H, Garcia-Diaz A, Hu-Lieskovan S, Kalbasi A, Grasso CS, Hugo W, Sandoval S, Torrejon DY, Palaskas N, Abril Rodriguez G, Parisi G, Azhdam A, Chmielowski B, Cherry G, Seja E, Berent-Maoz B, Shintaku IP, Le DT, Pardoll DM, Diaz LA, Tumeh PC, Graeber TG, Lo RS, Comin-Anduix B, Ribas A (Nov 2016). Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations. Cancer Discov.
Agarwal N (2016). Vaccine Therapy in Metastatic Renal Cell Carcinoma: Past, Present, and Future. ASCO Post. [Web]. Available: http://goo.gl/CqKjqd.
Homet Moreno B, Zaretsky JM, Garcia-Diaz A, Tsoi J, Parisi G, Robert L, Meeth K, Ndoye A, Bosenberg M, Weeraratna AT, Graeber TG, Comin-Anduix B, Hu-Lieskovan S Ribas A Corresponding Authors (Oct 2016). Response to programmed cell death-1 blockade in a murine melanoma syngeneic model requires costimulation, CD4, and CD8 T cells. Cancer Immunol Res, 4(10), 845-857.
D Stenehjem, S Gupta, M Wade, G Gilcrease, I Garrido-Laguna, JR Weis, J Whisenant, S Sharma (1 Oct 2016). A phase I dose escalation trial to assess the safety and preliminary efficacy of mFOLFOX6 combined with pembrolizumab (MK3475) in advanced gastrointestinal malignancies [Abstract]. Ann Oncol, 27(suppl_6), 1071.
Stenehjem D, Gupta S, Wade M, Gilcrease G, Garrido-Laguna I, Weis JR, Whisenant J, Sharma S (2016). A phase I dose escalation trial to assess the safety and preliminary efficacy of mFOLFOX6 combined with pembrolizumab (MK3475) in advanced gastrointestinal malignancies [Abstract]. Center for Investigational Therapeutics, Huntsman Cancer Institute, Salt Lake City, UT, USA, 2016.
Swami U, Ghalib MH, Chaudhary I, Hou JY, Aparo S, Einstein MH, Goldberg GL, Elrafei TN, Gajavelli S, Cohen B, Rajdev L, Kaubisch A, Haigentz M, Mani S, Goel S (2016). Risks and Benefits of phase I trials: Twelve years experience from a single institution [Abstract].
Swami U, Petrylak DP, Raftopoulos H, Shuster DE, Wang G, Kumar V, Martinez G, Goel S, Aisner J (2016). Phase IB study of eribulin mesylate in combination with carboplatin in patients with advanced solid tumors [Abstract].
Chaudhary I, Rajdev L, Swami U, Wilhelm F, Cohen B, Haigentz M, Kaubisch A, Goel S, Mani S, Ghalib MH (2016). Phase I dose-escalation study of ON 01910.Na in combination with oxaliplatin in patients with advanced solid tumors [Abstract].
Ohnuma T, Holland JF, Goel S, Wilck E, Lehrer D, Ghalib MH, Chaudhary I, Wilhelm F, Swami U, Mani S (2016). Final results of a Phase I dose-escalation study of ON01910.Na in combination with oxaliplatin in patients with advanced solid tumors [Abstract].
Park JW, et al, I-SPY2 Investigators (2016). Adaptive Randomization of Neratinib in Early Breast Cancer. New England Journal of Medicine, 375(1), 11-22.
Rugo HS, et al, I-SPY2 Investigators (2016). Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer. New England Journal of Medicine, 375(1), 23-34.
Tolcher A, Sznol M, Hu-Lieskovan S, Papadopoulos K, Patnaik A, Rasco D, DiGravio D, Huang8 B, Gambhire D, Chen Y, Pathan N, Wang K, Schmidt E, Chow L (June 2016). Phase 1b Study of Pf 05082566 in Combination With Pembrolizumab in Patients with Advanced Solid Tumors [Abstract]. 34(15 Supplement), Abstract 3002.
Bergerot PG, Sonpavde G, Nelson RA, Agarwal N, Costa CN, Hsu J, Choueiri TK, Pal SK (2016). Trends in neoadjuvant chemotherapy (NAC) use for muscle-invasive bladder cancer (MIBC): An updated report using the National Cancer Database (NCDB). Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 4540).
Alex A, Stenehjem DD, Twardowski P, Cheng HH, Gill DM, Buckley H, Patel SB, Kessler ER, Chittoria N, Poudel A, Vaishampayan UN, Agarwal N (2016). Impact of prior definitive therapy on survival outcomes in men with new hormone-sensitive metastatic prostate cancer (mHSPC) [Abstract]. Journal of Clinical Oncology, 34(suppl), abstr 5083.
Kuzman JA, Stenehjem DD, Patel SB, Merriman J, Gill DM, Hahn A, Agarwal AM, Gupta S, Albertson D, Alex A, Agarwal N (2016). Neutrophil-lymphocyte ratio (NLR) as a predictive biomarker for response to high dose interleukin 2 (HDIL-2) in patients with metastatic renal cell carcinoma (mRCC) [Abstract]. Journal of Clinical Oncology, 34(suppl), abstr e 16087.
Sonpavde G, Nagy RJ, Agarwal N, Gourdin TS, Naik G, Eshaghian S, Wang J, Armstrong AJ, Vaishampayan UN, Grivas P, Pal SK, Lanman RB, Talasaz A, Lilly MB (2016). Profiling of circulating tumor (ct)-DNA for potentially actionable targets in prostate cancer (PCa). Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL. [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 5035).
Alex A, Stenehjem DD, Twardowski P, Cheng HH, Gill DM, Buckley H, Patel SB, Kessler ER, Chittoria N, Poudel A, Vaishampayan UN, Agarwal N (2016). Impact of prior definitive therapy on survival outcomes in men with new hormone-sensitive metastatic prostate cancer (mHSPC). Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL. [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 5083).
Agarwal N, Tagawa ST, Chatta GS, Pal SK, Goel S, Mazhari R, Heaton C, Benaim E (2016). Results from a phase 1b/2 study of RX-0201, a novel AKT-1 antisense, combined with everolimus to treat metastatic clear cell renal carcinoma. Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL. [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 2559).
Agarwal N, Heemers H, Farnham JM, Patel SB, Gill DM, Gupta S, Teerlink C, Stephenson RA, Alex A, Cannon-Albright LA (2016). Association of single nucleotide polymorphisms (SNPs) in TPD52 gene with response to treatment with enzalutamide (ENZA) in men with metastatic castration refractory prostate cancer (mCRPC) [Abstract]. Journal of Clinical Oncology, 34(suppl), abstr 5066.
Agarwal N, Heemers H, Farnham JM, Patel SB, Gill DM, Gupta S, Teerlink C, Stephenson RA, Alex A, Cannon-Albright LA (2016). Association of single nucleotide polymorphisms (SNPs) in TPD52 gene with response to treatment with enzalutamide (ENZA) in men with metastatic castration refractory prostate cancer (mCRPC). Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 5066).
Pond GR, Sonpavde G, Plets M, Tangen CM, Hussain M, Lara P, Goldkorn A, Garzotto M, Mack PC, Higano CS, Vogelzang NJ, Thompson IM, Twardowski P, Van Veldhuizen PJ, Agarwal N, Carducci MA, Monk P, Quinn DI (2016). Validation of the association of RECIST 1.0 changes with survival in men with metastatic castration-resistant prostate cancer (mCRPC) treated on SWOG Study S0421. Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 5079).
Sonpavde G, Nelson RA, Trinh Q, Agarwal N, Nix J, Kardos S, Bellmunt J, Choueiri TK, Pal SK (2016). Adjuvant versus neoadjuvant chemotherapy for muscle-invasive bladder cancer (MIBC): Analysis of the National Cancer Database (NCDB). Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 4524).
Goldkorn A, Plets M, Agarwal N, Hussain M, Lara P, Vaena DA, MacVicar GR, Crispino T, Harzstark AL, Twardowski P, Tangen CM, Hugen CM, Xu T, Xu Y, Pinski JK, Ingles SA, Higano CS, Vogelzang NJ, Thompson IM, Quinn DI (2016). Circulating tumor cells (CTCs) in SWOG S1216: A phase 3 multicenter trial in metastatic hormone sensitive prostate cancer (mHSPC). Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL. [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 11516).
Nagy RJ, Agarwal N, Gupta S, Pal SK, Grivas P, Vaishampayan UN, Wang J, Naik G, Lanman RB, Talasaz A, Sonpavde G (2016). Circulating cell-free DNA profiling of patients with advanced urothelial carcinoma of the bladder. Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 4528).
Wells JC, Donskov F, Fraccon AP, Pasini F, Bjarnason GA, Knox JJ, Beuselinck B, Rha SY, Agarwal N, Brugarolas J, Lee JL, Pal SK, Srinivas S, Ernst DS, Vaishampayan UN, Wood L, Simpson R, Velasco G, Choueiri TK, Heng DYC (2016). Characterizing the outcomes of metastatic papillary renal cell carcinoma (papRCC). Poster Presentation. 2016 ASCO Annual Meeting, June 3-7, 2016, Chicago, IL [Abstract]. J Clin Oncol 34, 2016 (suppl; abstr 4554).
Bauer T, Adkins D, Schwartz GK, Werner TL, Alva AS, Hong DS, Carvaja RD, Saleh MN, Bazhenova L, Goel S, Eaton KD, Siegel RD, Wang D, Lauer RC, Neuteboom STC, Faltaos D, Chen I, Christensen J, Chao RC, Heist RS (2016). A first in human phase I study of receptor tyrosine kinase (RTK) inhibitor MGCD516 in patients with advanced solid tumors. [Abstract]. J Clin Oncol, 2016 ASCO Annual Meeting, 34(2016), suppl;abstr 2575.
Cohen A, Neumayer L, Factor R, Boucher K, Wade ML, Lamb JG, Arbogast K, Piccolo S, Shrestha G, Riegert J, Schabel M, Bild A, Werner TL (2016). A phase 1 window of opportunity study of valproic acid (VPA) in breast cancer testing a gene expression biomarker. [Abstract]. J Clin Oncol, 2016 ASCO Annual Meeting, 34(2016), suppl;abst 1084.
Gupta S, Weston A, Bearrs J, Thode T, Neiss A, Soldi R, Sharma S (2016). Reversible Lysine-Specific Demethylase 1 antagonist HCI-2509 inhibits growth and decreases c-myc in castration-resistant and docetaxel-resistant prostate cancer cells. Prostate Cancer Prostatic Dis.
Werner T, Sachdev J, Swisher E, Gutierrez M, Kittaneh M, Stein M, Xiong H, Dunbar M, Sullivan D, Ansell P, Hetman R, Komarnitsky P, McKee M, Tan A (2016). Veliparib (ABT-888) extended-release formulations: a phase 1 study on safety, pharmacokinetics (PK), and bioavailability in patients with advanced solid tumors. [Abstract]. J Clin Oncol, 2016 ASCO Annual Meeting, 34(2016), suppl;abstr 2579.
Boothe D, Williams, N, Odel B, Poppe M, Werner TL, Suneja G, Gaffney D (2016). The addition of adjuvant chemotherapy to radiation in high risk endometrial cancer: Survival outcomes and patterns of care. [Abstract]. J Clin Oncol, 2016 ASCO Annual Meeting, 34(2016), suppl;abstr 5587.
Nagy RJ, Agarwal N, Gupta S, Pal SK, Grivas P, Vaishampayan UN, Wang J, Naik G, Lanman RB, Talasaz AA, Sonpavde G (2016). Circulating cell-free DNA profiling of patients with advanced urotheial carcinoma of the bladderÏ [Abstract]. ASCO Annual Meeting 2016.
Agarwal N, Heemers H, Farnham JM, Patel SB, Gill D, Gupta S, Teerlink C, Stephenson RA, Alex A, Cannon-Albright LA (2016). Association of single nucleotide polymorphisms (SNPs) in TPD52 gene with response to treatment with enzalutamide (ENZA) in men with metastatic castration refractory prostate cancer (mCRPC) [Abstract]. 2016 ASCO.
Agarwal N (2016). Prognostication Based on Site of Metastatic Disease in Castration Refractory Prostate Cancer: Implications for Patient Care and Clinical Trial Design, Journal of Clinical Oncology [Podcast]. Available: https://goo.gl/YE04QE.
Agarwal N, Alex AB, Farnham JM, Patel SB, Gill D, Buckley TH, Stephenson RA, Cannon-Albright L (2016). Inherited variants in SULT1E1 and response to abiraterone acetate in men with metastatic castration refractory prostate cancer (mCRPC). J Urol.
Geiersbach K, Willmore-Payne C, Pasi Av, Paxton C, Werner TL, Xu X, Wittwer CT, Gulbahce HE, Downs-Kelly E (2016). Genomic Copy Number Analysis of HER2-Equivocal Breast Cancers. Am J Clin Pathol, Oct;146(4), 439-47.
Gupta S, Agarwal N (2016). Cancer Immunotherapy with Interleukin-2-Current Status and Future Developments. In Katrina Mountfort (Ed.), Oncology & Hematology Review (12, pp. 82-8).
Camp NJ, Lin W, Bigelow A, Burghel GJ, Mosbruger T, Parry M, Waller R, Rigas SH, Rajamanickam V, Cosby R, Brock IW, Jones B, Connley D, Sargent R, Wang G, Cannon-Albright LA, Werner TL, Factor RE, Bernard P, Knight S, Abo R, Reed MWR, Gertz J, Cox A (2016). Discordant Haplotype Sequencing Identifies Candidate Functional Variants from Disease-Association studies: Breast Cancer Risk at 2q33. doi: 10.1158/0008-5472.CAN-15-1629. PMID: 26795348. Cancer Research, 76(7), 1916-25.
Himes DO, Clayton MF, Donaldson GW, Ellington L, Buys SS, Kinney AY (2016). Breast Cancer Risk Perceptions among Relatives of Women with Uninformative Negative BRCA1/2 Test Results: The Moderating Effect of the Amount of Shared Information. PMID: 26245632. J Genet Couns, 25(2), 258-69.
Gupta S, Agarwal N (2016). Cancer Immunotherapy with Interleukin-2-Current Status and Future Developments [Web]. Immunotherapy. Available: https://goo.gl/pNFqvI.
Hugo W, Zaretsky JM, Sun L, Song C, Moreno BH, Hu-Lieskovan S, Berent-Maoz B, Pang J, Chmielowski B, Cherry G, Seja E, Lomeli S, Kong X, Kelley MC, Sosman JA, Johnson DB, Ribas A, Lo RS (Mar 2016). Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma. Cell, 165(1), 35-44.
Swami U, Abbi KKS, Dozeman L, Tricot A, Tricot GJ (2016). Cytomegalovirus and Human Herpes Virus-6 Reactivation Following Tandem Transplantation Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma (MM) [Abstract].
Robert L, Ribas A, Hu-Lieskovan S (February 2016). Combining targeted therapy with immunotherapy. Can 1 + 1 equal more than 2? [Review]. Semin Immunol, 28(1), 73-80.
Ramos, J, Wong YN, Crabb SJ, Niegisch G, Bellmunt J, Ladoire S, Hussain SA, Baniel J, Golshayan AR, Powles T, Rosenberg JE, Giorgi UD, Vaishampayan UN, Agarwal N, Pal SK, Harshman LC, Necchi A, Recine F, Galsky MD, Yu EY, RISC Investigators (2016). Venous thromboembolism (VTE) risk in patients with localized urinary tract tumors (UTT). Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 422).
Au TH, Bailey EB, Patel SB, Tantravahi SK, Agarwal N, Stenehjem DD (2016). Effect of concomitant proton pump inhibitor (PPI) on effectiveness of tyrosine kinase inhibitor (TKI) in patients with metastatic renal cell carcinoma (mRCC) [Abstract]. Journal of Clinical Oncology, 34(2S suppl), abstr 608.
Li H, Kroeger N, deVelasco G, Donskov F, Sim HW, Wells C, Stukalin I, Agarwal N, Parekh HD, Rini BI, Knox JJ, Pantuck AJ, Choueiri TK, Heng DYC (2016). The impact of active smoking on survival outcome in metastatic renal cell carcinoma patients treated with targeted therapy. Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 552).
Alex A, Stenehjem DD, Twardowski P, Cheng HH, Buckley TH, Gill DM, Patel SB, Vaishampayan U, Agarwal N (2016). Impact of prior definitive therapy on survival outcomes in men with new hormone sensitive metastatic prostate cancer (mHSPC) [Abstract]. Journal of Clinical Oncology, 34(2S suppl), abstr 269.
Parker SJ, Pond GR, Sonpavde G, Alex A, Heilbrun ME, Agarwal N (2016). Integration of bone scan (BS) and computerized tomography (CT) findings as an endpoint to assess bone metastasis in metastatic castration-resistant prostate cancer (mCRPC). Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 191).
Escudier BJ, Motzer RJ, Powles T, Tannir NM, Davis ID, Donskov F, Grunwald V, Heng DYC, Hutson T, Melichar B, Nosov D, Rini BI, Salman P, Sternberg CN, Szczylik C, Wolter P, Arroyo AM, Mangeshkar M, Agarwal N, Choueiri TK (2016). Subgroup analysis of METEOR, a randomized phase 3 trial of cabozantinib versus everolimus in patients (pts) with advanced renal cell carcinoma (RCC). Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 499).
Au TH, Bailey EB, Patel SB, Tantravahi SK, Agarwal N, Stenehjem DD (2016). Risk of hepatotoxicity with concurrent statin and tyrosine kinase inhibitor (TKI) or mTOR inhibitor (mTORi) in patients with metastatic renal cell carcinoma (mRCC) [Abstract]. Journal of Clinical Oncology, 34(2S suppl), abstr 610.
Buckley TH, Alex A, Franham JM, Gill DM, Patel SB, Teerlink C, Albright FS, Stephenson RA, Cannon-Albright LA, Agarwal N (2016). Association of single nucleotide polymorphisms (SNPs) in SULT1E1 with response to treatment with abiraterone acetate (AA) in men with metastatic castration refractory prostate cancer (mCRPC) [Abstract]. Journal of Clinical Oncology, 34(2S suppl), abstr 222.
Sonpavde G, Nagy RJ, Apolo AB, Agarwal N, Pal SK, Grivas P, Vaishampayan UN, Lanman RB, Talasaz A (2016). Circulating cell-free DNA profiling of patients with advanced urothelial carcinoma. Oral Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 358).
Au TH, Bailey EB, Patel SB, Tantravahi SK, Agarwal N, Stenehjem DD (2016). Risk of hepatotoxicity with concurrent statin and tyrosine kinase inhibitor (TKI) or mTOR inhibitor (mTORi) in patients with metastatic renal cell carcinoma (mRCC). Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 610).
Velasco G, Xie W, Donskov F, Albiges L, Beuselinck B, Srinivas S, Agarwal N, Lee JL, Brugarolas J, Wood L, Kollmannsberger CK, Rha SY, North SA, Kanesvaran R, Rini BI, Broom RJ, Yamamoto H, Kaymakcalan MD, Heng DYC, Choueiri TK (2016). DiscontinuingVEGF-targeted therapy (VEGF-TT) for progression versus toxicity impacts outcomes of second-line therapies in metastatic renal cell carcinoma (mRCC). Oral Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 503).
Davis ID, Xie W, Pezaro CJ, Donskov F, Wells C, Agarwal N, Srinivas Sandhya, Yuasa T, Beuselinck B, Wood L, Ernst DS, Kanesvaran R, Knox JJ, Pantuck AJ, Saleem S, Alva AS, Rini BI, Lee JL, Choueiri TK, Heng DYC (2016). Change in International mRCC Database Consortium (IMDC) prognostic category and implications for efficacy of second-line targeted therapy. Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 534).
Alex A, Stenehjem DD, Twardowski P, Cheng HH, Buckley TH, Gill D, Patel SB, Vaishampayan UN, Agarwal N (2016). Impact of prior definitive therapy on survival outcomes in men with new hormone sensitive metastatic prostate cancer (mHSPC). Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 269).
Gill D, Alex A, Farnham JM, Buckley TH, Patel SB, Agarwal AM, Teerlink C, Albright FS, Stephenson RA, Cannon-Albright LA, Agarwal N (2016). Association of single nucleotide polymorphism in four genes and response to androgen deprivation therapy (ADT) in men with advanced hormone sensitive prostate cancer (aHSPC). Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 224).
Gill DM, Alex A, Farnham JM, Buckley TH, Patel SB, Agarwal AM, Teerlink C, Albright FS, Stephenson RA, Cannon-Albright LA, Agarwal N (2016). Association of single nucleotide polymorphism in four genes and response to androgen deprivation therapy (ADT) in men with advanced hormone sensitive prostate cancer (aHSPC) [Abstract]. Journal of Clinical Oncology, 34(2S suppl), abstr 224.
Au TH, Bailey EB, Patel SB, Tantravahi SK, Agarwal N, Stenehjem DD (2016). Effect of concomitant proton pump inhibitor (PPI) on effectiveness of tyrosine kinase inhibitor (TKI) in patients with metastatic renal cell carcinoma (mRCC). Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 608).
Buckley TH, Alex A, Farnham JM, Gill D, Patel SB, Teerlink C, Albright FS, Stephenson, RA, Cannon-Albright LA, Agarwal N (2016). Assiciation of single nucleotide polymorphisms (SNPs) in SULT1E1 with response to treatment with abiraterone acetate (AA) in men with metastatic castration refractory prostate cancer (mCRPC). Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 222).
Bergerot PG, Nelson RA, Ye DW, Grivas P, Singh P, Agarwal N, Choueiri TK, Pal SK (2016). Risk of secondary urinary bladder cancer (UBC) in patients receiving radiotherapy for rectal cancer, prostate cancer, and gynecologic magnancies. Poster Presentation. 2016 Genitourinary Urinary Cancers Symposium, January 6-9, 2016, San Francisco, CA [Abstract]. J Clin Oncol 34, 2016 (suppl 2S; abstr 363).
Nathan Bahary, Ignacio Garrido-Laguna, Andrea Wang-Gillam, Asha Nyak-Kapoor, Eugene Kennedy, Nicholas N Vahanian, Charles J Link (2016). Results of the phase Ib portion of a phase I/II trial of the indoleamine 2,3-dioxygenase pathway (IDO) inhibitor indoximod plus gemcitabine/nab-paclitaxel for the treatment of metastatic pancreatic cancer. [Abstract]. J Clin Oncol 34, 2016 (suppl 4S; abstr 452).
Swami U, Abbi KKS, Dozeman L, Tricot A, Tricot GJ (2016). Cytomegalovirus and Human Herpes Virus-6 Reactivation Following Tandem Transplantation Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma (MM) [Abstract]. Biology of Blood and Marrow Transplantation, 22(3), S177-8.
Gupta S (2016). A Phase 2 Study of the Histone Deacetylase (HDAC) Inhibitor Mocetinostat in Patients with Urothelial Carcinoma (UC) and Inactivating Alterations of Acetyltransferase Genes [Abstract]. ASCO 2015 Annual Meeting.
Kharkar VJ, Ast A, Gupta S, Sharma S (2016). LSD2/KDM1B/AOF1 and Human Cancer Pathways: A Literature Review. Can Stu The J (1(1), pp. 1-5).
Singh P, Albertson D, Pal SK, Agarwal N (2016). Mucinous, Signet Ring, Ductal, and Sarcomatoid Variants of Prostate Cancer. In Lance Pagliaro (Ed.), Rare Genitourinary Tumors (First Edition). New York: Springer.
Agarwal N, Buckley TH, Farnham JM, Patel SB, Agarwal A, Tantravahi SK, Teerlink C, Albright FS, Stephenson RA, Alex A, Cannon-Albright LA (2016). Association of single nucleotide polymorphisms (SNPs) in STS and SULT2B1 and response to androgen deprivation therapy (ADT) in men with advanced hormone sensitive prostate cancer (aHSPC) [Abstract]. Clinical Cancer Research, 22(1 suppl), 39.
Evans E, Hu-Lieskovan S, Bussler H, Torno S, Mallow C, Reilly C, Scrivens M, Klimatcheva K, Winter LA, Kirk R, Howell A, Balch L, Veerarghavan J, Jonason Jr A, Leonard J, Paris M, Fisher T, Ribas T, Smith E, Zauderer M (December 2015). Antibody blockade of Semaphorin 4D Breaks Down Barriers To Enhance Tumoricidal Immune Infiltration And Supports Rational Immunotherapy Combinations [Abstract]. (4), Poster 1494.
Swami U, Dozeman L, Tricot A, Abbi KKS, Tricot GJ (2015). Collection of Peripheral Blood Stem Cells in Patients with Multiple Myeloma after Stem Cell Transplant: A Single Institution Experience [Abstract].
Patel SB, Mason CC, Glenn MJ, Paxton CN, South ST, Cessna MH, Asch J, Cobain EF, Bixby DL, Smith LB, Reshmi SR, Gastier-Foster JM, Schiffman JD, Miles RR (2015). Genomic analysis of adult B-ALL identifies changes in copy number profile at relapse and IKZF1/CDKN2A co-deletion at diagnosis as a marker of shorter survival [Abstract]. Blood, 126(23), 1427.
Swami U, Dozeman L, Tricot A, Abbi KKS, Tricot GJ (2015). Collection of Peripheral Blood Stem Cells in Patients with Multiple Myeloma after Stem Cell Transplant: A Single Institution Experience [Abstract]. Blood, 126(23), 5435.
Werner TL (December 2015). Chapter 4 - Breast Cancer Bone Metastases. In R. Lor Randall (Ed.), Metastatic Bone Disease: Essentials for the Orthopedic Surgeon (pp. 45-54). Springer International.
Hu-Lieskovan S, Patnaik A, Eisenberg P, Sachdev J, Weise A, PLX and Merck, Ribas T (November 2015). Phase 1/2a Study of Double Immune Suppression Blockade by Combining a CSF1R Inhibitor (Pexidartinib/PLX3397) with an anti PD-1 Antibody (Pembrolizumab) to Treat Advanced Melanoma and Other Solid Tumors [Abstract]. 26(Supplement 8), vii5.
Patel SB, Buckley TH, Tantravahi SK, Batten JA, Stenehjem DD, Alex A, Agarwal N (2015). Correlation of baseline serum testosterone (T) and serum prostate-specific antigen (PSA) at 7 months (7 mo PSA) in patients with new hormone sensitive metastatic prostate cancer (mHSPC) treated with continuous androgen deprivation therapy (cADT) [Abstract]. Journal of Clinical Oncology, 33(7 suppl), abstr 231.
Turner NC, et al, PALOMA3 Study Group (2015). Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer. New England Journal of Medicine, 373(3), 209-19.
Munster P, VanDer Noll R, Voest E, Specht J, Werner TL, Dees EC, Tan AR, Daud A, Schellens J, Lolkema MP, Griffin M, Agarwal N, Falchook GS, Kleha JF, Durante M, Smith DA, Adams L, Greshock J, Morris SR, Kurzrock R (2015). PI3K kinase inhibitor GSK2126458 (GSK458): Clinical activity in select patient (pt) populations defined by predictive markers (Study P3K112826). Oral Presentation European Society of Medical Oncology, September 2012, Vienna, Austria. [Abstract]. European Society of Medical Oncology. [Abstract]. Clinical Cancer Research.
Colonna SV, Curtin K, Kohlmann W, Wright J, Tavtigian S, Schiffman J (2015). Family history of breast cancer in Hodgkin disease and future risk of breast cancer. [Abstract]. J Clin Oncol, 33(suppl), abstr 1522.
Li H, Choueiri TK, Welss C, Agarwal N, Donskov F, Lee J, Broom RJ, Yuasa T, Rini BI, Pal SK, Wood L, Ernst DS, Kollmannsberger CK, Vaishampayan UN, Rha SY, Bjarnason GA, Knox JJ, Saleem S, Beuselinck B, Heng DYC (2015). Characteristics of metastatic renal cell carcinoma (mRCC) patients treated with delayed targeted therapy: Results from the International mRCC Consortium (IMDC). Poster Presentation. ASCO Annual Meeting May 29-June1, 2015, Chicago, IL [Abstract]. J Clin Oncol 33:5s, 2015 (suppl; abstr 4558).
Palmbos PL, Feng FY, Tomlins SA, Kelly WK, Morgans AK, Taplin M, Agarwal N, Antonarakis ES, Twardowski P, Jacobson J, Davenport MS, Daignault S, Knudsen KE, Hussain M (2015). A randomized phase II study of androgen deprivation therapy with or without PD0332991 in RB-positive metastatic hormone-sensitive prostate cancer. Poster Presentation. 2015 ASCO Annual Meeting May 29-June 1, 2015, Chicago, IL [Abstract]. J Clin Oncol 33:5s, 2015 (suppl; abstr TPS5074).
Agarwal N, Alex A, Farnham JM, Patel SB, Tantravahi SK, Teerlink C, Albright FS, Stephenson RA, Cannon-Albright LA (2015). Association of single nucleotide polymorphisms (SNPs) in ESR1 and PRMT8 and reponse to treatment with abiraterone acetate (AA) in men with metastatic castration refractory prostate cancer (mCRPC). Poster Presentation. ASCO Annual Meeting May 29-June 1, 2015, Chicago, IL [Abstract]. J Clin Oncol 33:5s, 2015 (suppl; abstr 5048).
Twardowski P, Plets M, Plimack ER, Agarwal N, Tangen CM, Vogelzang NJ, Thompson IM, Lara P (2015). SWOG 1107: Parallel (randomized) phase II evaluation of tivantinib (ARQ-197) and tivantinib in combination with erlotinib in patients (Pts) with papillary renal cell carcinoma (pRCC). Poster Presentation. 2015 ASCO Annual Meeting May 29-June 1, 2015, Chicago, IL [Abstract]. J Clin Oncol 33:5s, 2015 (suppl; abstr 4523).
Fay AP, Kwiatkowski DJ, Gray KP, Thorner A, Rini BI, Agarwal N, Ho TH, Song J, Barrios PM, Albiges L, Mendel Van Allen E, Krajewski KM, Porta C, Pal SK, Bellmunt J, McDermott DF, Heng DYC, Signoretti S, Choueiri TK (2015). Activating genomic mutations in the mTOR pathway to predict responses to everolimus and temsirolimus in patients with metastatic renal cell carcinoma (mRCC): Results from a large multi-institutional cohort. Poster Presentation. ASCO Annual Meeting May 29-June1, 2015, Chicago, IL [Abstract]. J Clin Oncol 33:5s, 2015 (suppl; abstr 4519).
Kohlmann W, Champine M, Colonna SV (May 31, 2015). Communicating Genetic Test Results to Patients and Their Families. ASCO Daily News.
Patel SB, Buckley TH, Gill D, Tantravahi SK, Batten JA, Stenehjem DD, Alex A, Agarwal N (2015). Correlation of baseline serum testosterone and serum prostate-specific antigen at 7 months in patients with new hormone sensitive metastatic prostate cancer treated with continuous androgen deprivation therapy [Abstract]. Journal of Clinical Oncology, 33(15 suppl), e16019.
Patel SB, Stenehjem DD, Hsu J, Tantravahi SK, Gill D, Agarwal A, Batten JA, Agarwal N, Pal SK (2015). Comparative effectiveness of first line vascular endothelial growth factor inhibitor followed by second line therapy with either a VEGF-TKI or an mTOR inhibitor in patients with metastatic renal cell carcinoma [Abstract]. Journal of Clinical Oncology, 33(15 suppl), e15589.
Bailey E, Tantravahi SK, Poole A, Wells C, Batten J, Merriman J, Stenehjem D, Agarwal N (May 2015). Association of hand-foot syndrome (HFS), treatment dose reductions (TDRs), and outcomes in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with vascular endothelial growth factor (VEGF) tyrosine kinase inhibitors (TKIs). Poster Presentation. 2014 ASCO Annual Meeting May 30-June 3, 2014, Chicago, IL [Abstract]. J Clin Oncol.
H Park, I Garrido-Laguna, A Naing, S Fu, GS Falchook, SA Piha-Paul, JJ Wheler, DS Hong, V Subbiah, AM Tsimberidou, AO Kaseb, Y Oki, R Zinner, S Patel, V Velez Bravo, MA Fanale, F Meric Bernstam, R Kurzrock, F Janku (2015). Phase 1 study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancies. ASCO Annual Meeting May 29-June 2,2015 [Abstract]. J Clin Oncol, 33, 2015(suppl; abstr 2584)).
K Wang, A Johnson, I Garrido-Laguna, J Chmielecki, R Yelensky, D Lipson, JA Elvin, JA Vergilio, SA Ali, V Miller, PJ Stephens, JS Ross (2015). Amplification of CRKL in human cancer: a rare event associated with potential sensitivity to targeted therapy. ASCO Annual Meeting May 29-June 2,2015. Abstract Number: 1526 [Abstract]. J Clin Oncol, 33, 2015(suppl; abstr 1526).
DS Hong, I Garrido-Laguna, IE Krop, V Subbiah, TL Werner, CM Cotter, EP Hamilton, K Velastegui, D Xuan, R Bugarini, A Gollerkeri, HA Burris (2015). First-in-human dose escalation, safety, and PK study of a novel EFNA4-ADC in patients with advanced solid tumors. ASCO Annual Meeting May 29-June 2,2015 (Abst. # to be released on May 13th) [Abstract].
WS Liang, B Salhia, A Helland, S Sekar, I Garrido-Laguna, M Fanale, Y Oki, JR Westin, RE Davis, F Meric-Bernstam, F Janku (2015). Identification of mutations in histrone modification genes in Hodgkin lymphoma. AACR 106th Annual Meeting, April 18-22 (LB-176) [Abstract].
Moore KN, Sill MW, Tenney ME, Darus CJ, Griffin D, Werner TL, Rose PG, Behrens R (2015). A Phase II Trial of Trebananib (AMG 386; IND#111071), a Selective Angiopoietin 1/2 Neutralizing Peptibody, in Patients with Persistent/Recurrent Carcinoma of the Endometrium: A Gynecologic Oncology Group Study [Abstract]. SGO March 2015, 137(supp 1), 24.
Williams NL, Werner TL, Jarboe EA, Gaffney DK (2015). Adenocarcinoma of the cervix: should we treat it differently? [Review]. Curr Oncol Rep, 2015 Apr, 17(4):17.
Gupta S, Weston A, Bearrs J, Soldi R, Sharma S (2015). Effect of LSD-1 inhibition on docetaxel resistance in prostate cancer cells [Abstract]. AACR Annual Meeting, April 2015.
Flaig TW, Tangen CM, Hussain M, Agarwal N, Mitsiades N, Deshpande HA, Vaishampayan UN, Thompson IM (February 2015). Phase II trial of abiraterone acetate (AA) treatment for metastatic prostate cancer (PC) patients with a PSA of more than four following initial androgen deprivation therapy: SWOG S1014. Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Locke JA, Pond GR, Sonpavde G, Necchi A, Giannatempo P, Paluri RK, Niegisch G, Albers P, Buonerba C, Lorenzo G, Vaishampayan UN, North SA, Agarwal N, Hussain SA, Eigl BJ (February 2015). Impact of first-line cisplatin versus non-cisplatin based chemotherapy on progression-free survival in patients with advanced urothelial carcinoma previously treated with perioperative cisplatin based chemotherapy. Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Ramos J, Casey MF, Crabb SJ, Bamias A, Harshman LC, Wong YN, Bellmunt J, De Giorgi U, Ladoire S, Powles T, Pal SK, Niegisch G, Sternberg CN, Alva AS, Agarwal N, Necchi A, Vaishampayan UN, Rosenberg JE, Galsky MD, Yu EY (February 2015). Impact of chemotherapy (CTX) on venous thromboembolism (VTE) and prognostic implications in patients with metastatic urinary tract tumors (UTT). Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Buckley TH, Patel SB, Tantravahi SK, Batten JA, Stenehjem DD, Alex A, Agarwal N (2015). Correlation of baseline serum testosterone and serum prostate-specific antigen at 7 months in patients with new hormone sensitive metastatic prostate cancer treated with continuous androgen deprivation therapy [Abstract]. Journal of Clinical Oncology, 33(7 suppl), abstr 231.
Shiven B Patel, Danielle Tometich, Zachary L Reese, Sunil Sharma, Ignacio Garrido-Laguna (2015). Exceptional responses in patients with metastatic colorectal cancer enrolled in first-in-man studies from 2002 through 2012. Presented at the 2015 Gastrointestinal Cancers Symposium [Abstract]. J Clin Oncol, 33(suppl 3 abstr 687).
Zachary L Reese, Danielle Tometich, Shiven B Patel, Sunil Sharma, Ignacio Garrido-Laguna (2015). Exceptional responses in patients with upper gastrointestinal malignancies enrolled in first-in-man studies: 2002-2012. Presented at the 2015 Gastrointestinal Cancers Symposium., Abstract 311 [Abstract]. J Clin Oncol, 33(suppl 3), abstr 311.
Agarwal N, Buckley TH, Farnham JM, Patel SB, Alex A, Teerlink C, Albright FS, Stephenson RA, Cannon-Albright LA (February 2015). Germ line predictors of response to androgen deprivation therapy in men with advanced prostate cancer. Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Albright FS, Agarwal N, Lowrance WT, Stephenson RA, Alex A, Cannon-Albright LA (February 2015). Risk for death from prostate cancer predicted from complete family history of lethal prostate cancer (LPC). Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Patel SB, Agarwal N, Hsu J, Tantravahi SK, Gill D, Vuong W, Batten JA, Stenehjem DD, Pal SK (February 2015). Everolimus (EVE) versus temsirolimus (TEM) after first-line treatment with VEGF TKI in patients with metastatic renal cell carcinoma. Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Buckley TH, Patel SB, Tantravahi SK, Batten JA, Stenehjem DD, Alex A, Agarwal N (February 2015). Correlation of baseline serum testosterone (T) and prostate-specific antigen (PSA) at 7 months (7 mo PSA) in patients (pts) with new hormone sensitive metastatic prostate cancer (mHSPC) treated with continous androgen deprivation therapy (cADT). Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Patel SB, Tantravahi SK, Gill D, Poole A, Merriman J, Batten JA, Stenehjem DD, Agarwal N (February 2015). Comparative effectiveness of first-line VEGF TKI followed by second-line therapy with either a VEGF TKI or an mTOR in patients with metastatic renal cell carcinoma. Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Cannon-Albright LA, Teerlink C, Alex A, Albright FS, Stephenson RA, Agarwal N (February 2015). A genome-wide linkage study of lethal prostate cancer predisposition gene in a set of high-risk pedigrees. Poster Presentation. 2015 Genitourinary Cancers Symposium. February 26-28, 2015. Orlando, FL [Abstract]. J Clin Oncol.
Sharma S, Hu-Lieskovan S, Dubinett SM, Moon Lee J (2015). Addressing inflammation with immunotherapy. In Dubinett S (Ed.), Inflammation and Lung Cancer (Second Edition). New York: Springer.
Agarwal N, Buckley TH, Farnham JM, Patel SB, Alex A, Teerlink C, Albright FS, Stephenson RA, Cannon-Albright LA (2015). Germline predictors of response to androgen deprivation therapy in men with advanced prostate cancer [Abstract]. Journal of Clinical Oncology, 33(7 suppl), abstr 162.
Patel SB, Tometich D, Reese ZL, Sharma S, Garrido-Laguna I (2015). Exceptional responses in patients with metastatic colorectal cancer enrolled in first-in-man studies from 2002-2012 [Abstract]. Journal of Clinical Oncology, 33(3 suppl), 687-687.
Reese ZL, Tometich D, Patel SB, Sharma S, Garrido-Laguna I (2015). Exceptional responses in patients with upper gastrointestinal malignancies enrolled in first-in-man studies: 2002-2012 [Abstract]. Journal of Clinical Oncology, 33(3 suppl), abstr 311.
Pendurti G, Shah U, Swami U, Hou Y, Ghalib MH, Chaudhary I, Polineni R, Klobocista M, Mukherjee P, Chuy JW, Kaubisch A, Rajdev L, Aparo S, Goel S (2015). Developing a novel prognostic model to predict overall survival (OS) and 90 day mortality rate (90DM) for metastatic colorectal cancer (mCRC) patients in phase I trials [Abstract]. J Clin Oncol, 33(suppl; abstr e14618).
Tantravahi SK, Patel SB, Ravulapati S, Batten J, Merriman J, Stenehjem DD, Agarwal N (2015). Long term response in metastatic renal cell carcinoma patients receiving first line therapy with vascular endothelial growth factor inhibitors with VEGF TKIs [Abstract]. Journal of Clinical Oncology, 33(7 suppl), abstr 436.
Colonna SV, Werner T (2015). Breast cancer bone metastases. In Lor Randall (Ed.), Metastatic Bone Disease: Essentials for the Orthopedic Surgeon. Springer International.
Swami U, Shah U, Goel S (2015). Marine sponge derived Eribulin in preclinical and clinical studies for cancer. In Handbook of Anticancer Drugs from Marine Origin (pp. 59-100). Cham, Switzerland: Springer International Publishing.
Gilcrease GW, Kinsey C, Stenehjem D (2015). Environmental and genetic risk factors in hepatocellular carcinoma. In Torre A, Uscanga L (Eds.), Medicina Individualizada De La Evidencia A La Práctica Clínica (pp. 155-62). Permanyer México.
Patel SB, Agarwal N, Hsu J, Tantravahi SK, Gill D, Vuong W, Batten JA, Stenehjem DD, Pal SK (2015). Everolimus (EVE) versus temsirolimus (TEM) after first-line treatment with VEGF TKI in patients with metastatic renal cell carcinoma [Abstract]. Journal of Clinical Oncology, 33(7 suppl), abstr 460.
Maughan BL, Suzman DL, Nadal R, Bassi S, Schweizer MT, Antonarakis ES (2015). Optimal sequencing of docetaxel and abiraterone in men with metastatic castration-resistant prostate cancer (mCRPC) [Abstract]. J Clin Oncol, 33(Suppl 7), abstr 252.
Patel SB, Tantravahi SK, Gill D, Poole A, Merriman J, Batten JA, Stenehjem DD, Agarwal N (2015). Comparative effectiveness of first line vascular endothelial growth factor inhibitor followed by second line therapy with either a VEGF-TKI or an mTOR inhibitor in patients with metastatic renal cell carcinoma [Abstract]. Journal of Clinical Oncology, 33(7 suppl), abstr 495.
Gupta S (2015). Epigenetics in Bladder Cancer. Focus on Phase I Newsletter.
Agarwal N, Alex A, Farnham JM, Patel SB, Tantravahi SK, Teerlink C, Albright FS, Stephenson RA, Cannon-Albright LA (2015). Association of single nucleotide polymorphisms in ESR1 and PRMT8 and response to treatment with abiraterone acetate in men with metastatic castration refractory prostate cancer [Abstract]. Journal of Clinical Oncology, 33(suppl), abstr 5048.
Goyal A, Soul D, Annunziata G, Swami U, Choudhury M (Winter 2014). A self destructing reaction to a self destructive habit: Levamisole tainted cocaine causing autoimmune vasculitis. New York Medical Journal, 8(1).
Agarwal N (2014). Perspective opinion on “Gleason score associated with time to development of neuroendocrine prostate cancer [Web]. Available: https://goo.gl/eKj1Q1.
Antonis C Antoniou, Silvia Casadei, Tuomas Heikkinen, Daniel Barrowdale, Katri Pylks, Jonathan Roberts, Andrew Lee, Deepak Subramanian, Kim De Leeneer, Florentia Fostira, Eva Tomiak, Susan L Neuhausen, Zhi L Teo, Sofia Khan, Kristiina Aittomki, Jukka S Moilanen, Clare Turnbull, Sheila Seal, Arto Mannermaa, Anne Kallioniemi, Geoffrey J Lindeman, Buys SA, Irene L Andrulis, Paolo Radice, Carlo Tondini, Siranoush Manoukian, Amanda E Toland, Penelope Miron, Jeffrey N Weitzel, Susan M Domchek, Bruce Poppe, Katheen BM Claes, Drakoulis Yannoukakos, Patrick Concannon, Jonine L Bernstein, Paul A James, Douglas F Easton, David E Goldgar, John L Hopper, Nazneen Rahman, Paolo Peterlongo, Heli Nevanlinna, Mary-Claire King, Fergus J Couch, Melissa C Southey, Robert Winqvist, William D Foulkes, Marc Tischkowitz (2014). Inherited Loss-of-Function Mutations in PALB2 and Breast Cancer Risk. N Engl J Med, 371, 497-506.
Agarwal N, Tangen C, Hussain M, Lara Jr P, Higano C, Vaena D, MacVicar G, Li H, Crispino T, Quinn D, Vogelzang N, Thompson Jr I (May 2014). SWOG S1216: A phase III randomized trial comparing androgen deprivation therapy (ADT) + TAK-700 with ADT + bicalutamide in patients with newly diagnosed metastatic hormone sensitive prostate cancer (HSPC) (NCT01809691). Poster Presentation. 2014 ASCO Annual Meeting May 30-June 3, 2014, Chicago, IL Accepted. [Abstract].
Shepard D, Bruce J, Garrido-Laguna I, et al (2014). Phase Ib study of axitinib in combination with crizotinib in patients with advanced solid tumors [Abstract]. J Clin Oncol 32:5s, 2014 (suppl; abstr TPS4596).
Hu-Lieskovan S, Mok S, Robert L, Goedert L, Comin-Anduix B, Koya RC, Ribas A (June 2014). Combinatorial effect of dabrafenib, trametinib, and adoptive cell transfer (ACT) in an immune-competent murine model of BRAFV600E mutant melanoma [Abstract]. 32(5 Supplement), Abstract 2512.
Cheng H, Li H, Higano C, Tangen C, Agarwal N, Yan J, Vogelzang N, Hussain M, Thompson Jr I, Tewari M, Yu E (May 2014). Comparison of plasma microRNAs with CTCs and PSA in patients treated on SWOG S0925, a randomized phase II study of androgen deprivation combined with cixutumumab versus androgen deprivation alone for patients with new metastatic hormone-sensitive prostate cancer. Poster discussion session. 2014 ASCO Annual Meeting May 30-June 3, 2014, Chicago, IL Accepted. [Abstract].
Galsky M, Harshman L, Crabb S, Wong YN, Yu E, Chowdhury S, Powles T, Pal SK, Moshier E, Ladoire S, Hussain S, Agarwal N, Vaishampayan U, Recine F, Berthold D, Necchi A, Theodore C, Milowsky M, Bellmunt J, Rosenberg J (May 2014). Comparative effectiveness of gemcitabine plus cisplatin (GC) versus methotrexate, vinblastine, doxorubicin, plus cisplatin (MVAC) as neoadjuvant therapy for muscle-invasive bladder cancer (MIBC). Poster discussion session. 2014 ASCO Annual Meeting May 30-June 3, 2014 Chicago, IL Accepted. [Abstract].
Merriman J, Parikh K, Tantravahi SK, Straubhar AM, Agarwal A, Sendilnathan A, Van Atta J, Batten J, Grossmann K, Samlowski W, Stenehjem D, Agarwal N (May 2014). Correlation of stable disease (SD) as best response with survival outcomes in patients (pts) with clear cell (cc) metastatic renal cell carcinoma (mRCC) treated with high-dose interleukin-2 (HD IL-2). Poster Presentation. 2014 ASCO Annual Meeting May 30–June 3, 2014, Chicago, IL [Abstract]. J Clin Oncol.
Diamond JR, Agarwal N, Bowles D, Lam ET, Werner T, Wu B, Rasmussen E, Gamelin E, Soto F, Friberg G, Sun YN, Sharma S (May 2014). Evaluation of pharmacokinetic (PK) drug-drug interactions (DDI) between trebananib (AMG 386) and paclitaxel (PTX) in patients (pts) with advanced solid tumors. Poster Presentation. 2014 ASCO Annual Meeting May 30-June 3, 2014 Chicago, IL Accepted. [Abstract].
Albiges L, Xie W, Lee JL, Rini B, Srinivas S, Bjarnason G, Ernst S, Wood L, Vaishamayan U, Rha SH, Agarwal N, Yuasa T, Pal SK, Koutsoukos K, Fay AP, Preston M, Cho E, Chin Heng DY, Choueiri T (May 2014). The impact of body mass index (BMI) on treatment outcome of targeted therapy in metastatic renal cell carcinoma (mRCC): Results from the international metastatic renal cell cancer database consortium. Poster Presentation. 2014 ASCO Annual Meeting May 30-June 3, 2014 Chicago, IL Accepted. [Abstract].
Fizazi K, Jones R, Oudard S, Efstathiou E, Saad F, De Wit R, De Bono JS, Cruz F, Fountzilas G, Ulys A, Carcano F, Agarwal N, Agus D, Bellmunt J, Petrylak P, Lee C, Tejura B, Borgstein NG, Dreicer R (May 2014). Regional differences observed in the phase 3 trial (ELM-PC 5) with orteronel (TAK-700) plus prednisone in patients with metastatic castration-resistant prostate cancer (mCRPC) that has progressed during or following docetaxel. Poster Presentation. 2014 ASCO Annual Meeting May 30-June 3, 2014 Chicago, IL Accepted. [Abstract].
Merriman J, Parikh K, Tantravahi SK, Straubhar AM, Agarwal A, Sendilnathan A, Van Atta J, Batten J, Grossmann K, Samlowski W, Stenehjem D, Agarwal N (May 2014). Correlation of stable disease (SD) as best response with survival outcomes in patients (pts) with clear cell (cc) metastatic renal cell carcinoma (mRCC) treated with high-dose interleukin-2 (HD IL-2). Poster Presentation. 2014 ASCO Annual Meeting May 30-June 3, 2014, Chicago, IL Accepted. [Abstract].
Reynolds K, Juric D, Baselga J, Garrido-Laguna I, Bang, Y et al (2014). A Phase 1 study of LJM716 in patients with esophageal squamous cell carcinoma, head and neck cancer or HER2-overexpressing metastatic breast or gastric cancer [Abstract]. J Clin Oncol 32:5s, 2014 (suppl; abstr 2517), 2014 ASCO Annual Meeting.
Yu E, Tangen C, Higano C, Agarwal N, Pal SK, Alva AS, Heath E, Tat Lam E, Gupta S, Lilly M, Inoue Y, Chi K, Vogelzang N, Quinn D, Li H, Cheng H, Plymate S, Hussain M, Thompson Jr I (May 2014). SWOG S0925: A randomized phase 2 study of androgen deprivation combined with cixutumumab versus androgen deprivation alone in patients with new metastatic hormone-sensitive prostate cancer. Oral Presentation. 2014 ASCO Annual Meeting May 30-June 3, 2014, Chicago, IL Accepted. [Abstract].
Agarwal N, Parikh K, Tantravahi SK, Van Atta J, Batten J, Sageser D, Samlowski W, Grossmann K, Wang J, Stenehjem D (May 2014). Clinical benefit (CB) of high-dose interleukin-2 (HD IL-2) in clear cell (cc) metastatic renal cell carcinoma (mRCC). Poster Presentation. 2014 ASCO Annual Meeting May 30-June 3, 2014, Chicago, IL Accepted. [Abstract]. Journal of Clinical Oncology.
Garrido-Laguna I, Tometich D, Hu Nan, Boucher K, Sharma S (2014). N of 1 Case Reports of Exceptional Responders Among Pancreatic Cancer Patients Enrolled in First-in-man studies from 2002 through 2012. Pancreatic Cancer: Innovation in Research and Treatment 2014 New Orleans, abst # B93 [Abstract].
Tantravahi SK, Stenehjem DD, Agarwal A, Kollepara SL, Batten JA, Ward M, Albertson D, Wang JF, Liu T, Agarwal N (January 2014). Clinical outcomes and survival of patients (pts) with sarcomatoid metastatic renal cell carcinoma (smRCC). Poster Presentation. 2014 Genitourinary Cancers Symposium. January 30-February 1, 2014, San Francisco, CA. [Abstract]. Journal of Clinical Oncology, 32(suppl 4), abstr 535.
Ko JJ, Xie W, Heng DY, Kroeger N, Lee JL, Rini BI, Knox JJ, Bjarnason GA, Harshman LC, Pal SK, Yuasa T, Smoragiewicz M, Donskov F, Bamias A, Wood L, Ernst DS, Agarwal N, Vaishampayan UN, Rha SY, Choueiri TK (January 2014). The international metastatic renal cell carcinoma database consortium (IMDC) model as a prognostic tool in metastatic renal cell carcinoma (mRCC) patients previously treated with first-line targeted therapy (TT). Oral Presentation. 2014 Genitourinary Cancers Symposium. January 30-February 1, 2014, San Francisco, CA. [Abstract]. Journal of Clinical Oncology, 32(suppl 4), abstr 398.
Heng DY, Rini BI, Beuselinck B, Lee JL, Knox JJ, Bjarnason GA, Pal SK, Kollmannsberger CK, Yuasa T, Srinivas S, Donskov F, Bamias A, Wood L, Ernst DS, Agarwal N, Vaishampayan UN, Rha SY, Kim JJ, Kanesvaran R, Choueiri TK (January 2014). Cytoreductive nephrectomy (CN) in patients with synchronous metastases from renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC). Oral Presentation. 2014 Genitourinary Cancers Symposium. January 30-February 1, 2014, San Francisco, CA. [Abstract]. Jorunal of Clinical Oncology, 32(suppl 4), abstr 396.
Batten JA, Samlowski W, Parikh K, Sendilnathan A, Van Atta J, Batten JA, Sagesser D, Grossmann K, Tantravahi SK, Stenehjem DD, Agarwal N (January 2014). The association between rigors and overall survival (OS) in metastatic renal cell carcinoma (mRCC) patients treated with high-dose interleukin-2 (HD IL-2) Poster Presentation. 2014 Genitourinary Cancers Symposium. January 30-February 1, 2014, San Francisco, CA. [Abstract]. Journal of Clinical Oncology, 32(suppl 4), abstra 487.
Cheng HH, Nadal R, Gulati R, Azad A, Twardowski P, Vaishampayan U, Agarwal N, Heath E, Pal SK, Rehman H, Leiter A, Batten J, Montgomery RB, Galsky MD, Chi KN, Antonarakis ES, Yu EY (January 2015). The Effect of Prior Abiraterone (Abi) Use on the Efficacy of Enzalutamide (Enza) in Men with mCRPC. Poster Presentation. 2014 Genitourinary Cancers Symposium. January 30-February 1, 2014, San Francisco, CA. [Abstract]. Journal of Clinical Oncology, 32(suppl 4), abstr 18.
Parikh K, Stenehjem DD, Sendilnathan A, Crispin H, VanAtta J, Batten JA, Sagesser D, Grossmann K, Samlowski W, Tantravahi SK, Agarwal N (January 2014). Conditional survival of metastatic renal cell carcinoma (mRCC) patients treated with high dose interleukin-2 (HD-IL2). Poster Presentation. 2014 Genitourinary Cancers Symposium. January 30-February 1, 2014, San Francisco, CA. [Abstract]. Journal of Clinical Oncology, 32(suppl 4), abstr 460.
Tsao CK, Agarwal N, Apolo AB, Lee KM, Godbold JH, Oh WK, Galsky MD (January 2014). Phase Ib/II trial of gemcitabine, cisplatin, plus lenalidomide as first-line therapy for patients with metastatic urothelial carcinoma. Poster Presentation. 2014 Genitourinary Cancers Symposium. January 30-February 1, 2014, San Francisco, CA. [Abstract]. Journal of Clinical Oncology, 32(suppl 4), abstr 18.
Diamond JR, Agarwal N, Bowles DW, Lan ET, Werner TL, Wu B, Rasmussen E, Gamelin E, Soto F, Friberg G, Sun YN, Sharma S (2014). Evaluation of pharmacokinetic (PK) drug-drug interactions (DDI) between trebananib and paclitaxel (PTX) in patients (pts) with advanced solid tumors [Abstract]. ASCO Annual Meeting, 2014, Chicago, Illinois.
Khan A, Laronde DM (2014). Waterpipe smoking - a "healthy" alternative to cigarettes or a health hazard in disguise. [Review]. Canadian Journal of Dental Hygiene, 48(1), 27-33.
Poole A, Alva A, Batten JA, Agarwal N (2014). Metastatic Castrate Resistant Prostate cancer: Role of Androgen Signaling Inhibitors. In Dicker AP, Trabulsi EJ, Kelly W (Eds.), Multidisciplinary Approach to Prostate Cancer. New York: Demos Medical Publishing.
Halwani A, Colonna SV, Ying J, Buys S, Sweeney C (2014). Geographic distribution of rural-urban status of women with breast cancer in the Veterans Health Administration using two schemes: Rural Urban Continuum and Rural Urban Commuting Areas [Abstract]. Association of VA Hematology/Oncology.
Colonna SV, Halwani A, Ying J, Sweeney C, Buys S (2014). Breast cancer treatment among rural and urban veterans at the Veterans Health Administration: also presented as a poster. [Abstract]. Association of VA Hematology/Oncology.
Agarwal N, Fishman M (2014). Immunologic Therapy of Renal Cell Carcinoma. In Oncology & Hematology Review (10, pp. 54-60).
Janku F, Garrido-Laguna I, Velez-Bravo V et al (2013). Significant activity of the mTOR inhibitor sirolimus and HDAC inhibitor vorinostat in heavily pretreated refractory Hodgkin lymphoma patients [Abstract]. Blood (ASH Annual Meeting Abstracts), 122(21), 3048.
Udomaksorn S, Stenehjem D, Welch BM, Cheng Y, Anderson L, Colonna S, Neumayer L, Brixner D (2013). Evaluation of variable relevance and accessibility to support personalized medicine in breast cancer [Abstract]. ISPOR 16th Annual European Congress, Dublin, Ireland.
Colonna SV, Higgins AK, Alvarez J, Saville B, Lawrence JA, Abramson VA (2013). Analysis of recurrence risk by subtype in <1cm breast tumors [Abstract]. Journal of Clinical Oncology.
Sonpavde G, Pond GR, Agarwal N, Choueiri TK, Qu AQ, Fougeray R, Salhi Y, Vaughn DJ, James ND, Niegisch G, Albers P, Galsky MD, Wong YN, Stadler WM, ODonnell PH, Vogelzang NH, Sridhar SS, Ko YJ, Sternberg CN, Bellmunt J (2013). Nomogram to estimate the activity of second-line therapy for advanced urothelial carcinoma (UC). Poster Discussion. American Society of Clinical Oncology (ASCO) Annual Meeting Chicago IL. May 31-Jun 4, 2013. [Abstract].
Chittoria N, Zhu H, Choueiri TK, Kroeger N, Lee JL, Srinivas S, Knox J, Bjarnason BA, MacKenzie MK, Wood L, Vaishamayan UN, Agarwal N, Pal SK, Tan MH, Rha SY, Yuasa T, Donskov F, North SA, Rini BI, Yick D, Heng C (2013). Outcome of metastatic sarcomatoid renal cell carcinoma (sRCC): Results from the International mRCC Database Consortium. Poster Presentation. May 31-Jun 4, 2013.ASCO annual meeting Washington D.C. [Abstract].
Cohen AL, Factor R, Schabel M, Bild A, Werner TL (2013). Effect of short course, high-dose valproic acid on proliferation in breast adenocarcinomas. [Abstract]. Journal of Clinical Oncology, 2013 ASCO Annual Meeting Abstracts 31:15s, 2013(May 20 Supplement), e13522.
Agarwal N, Wade M, Batten J, Davidson C, Sun SL, Sharma S (2013). Phase I Study of Histone Deacetylase Inhibitor Belinostat in Combination with Warfarin in Patients with Solid Tumors or Hematological Malignancies. Accepted for Poster Presentation (Abstract: 1187): April, 8, 2013 AACR annual meeting. Washington, DC [Abstract].
Dunson, W, Mooney K, Beck S, Wong B, Wujcik D (2013). NCCN Symptom Guidelines Coupled with Nurse Practitioner Follow-up Reduce Moderate to Severe Symptom Days by Half or Greater in Cancer Patients Receiving Outpatient Chemotherapy [Abstract]. Journal of the National Comprehensice Cancer Network, 11/Number 3(March 2013), 244.
Kollepara SS, Tantravahi SK, Batten J, Agarwal N (2013). Integrating Emerging Science into Clinical Practice:Targeting Androgen Signaling in Castration Resistant Metastatic Prostate Cancer”. In Lopaczynski W, Srivastava R, and Maksymowicz W. (Eds.), Lost in Translation: Barriers in Incentives for Translational Research. Singapore: World Scientific Publishing Co Pte. Ltd.
Forero A, Vaklavas C, LoBuglio AF (2013). Brentuximab Vedotin (SGN-35) for CD30 Positive Malignancies. In Antibody- Drug Conjugates and Immunotoxins: From Pre-Clinical Development to Therapeutic Applications; Cancer Drug Discovery and Development series (pp. 161-75). Springer.
Vaklavas C, LoBuglio AF, Saleh M, Yelin M, Forero A (2013). CDX-011 (Glembatumumab Vedotin, CR011-vcMMAE). In Antibody-Drug Conjugates and Immunotoxins: From Pre-Clinical Development to Therapeutic Applications; Cancer Drug Discovery and Development series (pp. 211-20). Springer.
Shah U, Pendurti G, Swami U, Hou Y, Ghalib MH, Chaudhary I, Mani S, Goel S, Aparo S (2013). Clinical outcome for patients with metastatic colorectal cancer (mCRC) enrolled in phase I clinical trials: Single institution experience [Abstract]. J Clin Oncol, 31(suppl; abstr e13550).
Samadder NJ, Curtin K, Wong J, Pappas L, Tuohy T, Mineau G, Smith K, Pimentel R, Boucher K, Garrido-Laguna I, Provenzale D, Burt, R (2013). Epidemiology and Familial Risk of Synchronous and Metachronous Colorectal Cancer: A Population-based Study in Utah. Abs P599, ACG Annual Meeting, San Diego 2013 [Abstract].
Munster P, van der Noll R, Voest E, Specht J, Werner TL, Dees EC, Tan AR, Daud A, Schellens J, Lolkema MP, Griffin M, Agarwal N, Falchook GS, Kleha JF, Durante M, Smith DA, Adams L, Greshock J, Morris SR, Kurzrock R (9/2012). PI3K kinase inhibitor GSK2126458 (GSK458): Clinical activity in select patient (pt) populations defined by predictive markers (Study P3K112826). Oral Presentation European Society of Medical Oncology, September 2012, Vienna, Austria. [Abstract]. European Society of Medical Oncology.
Kinney A, Birmingham W, Kohlmann W, Agarwal N (August 2012). Patients and providers cognitions regarding genomic risk assessments for prostate cancer susceptibility and cancer prevention. Oral Presentation Aug 2012 Prague, Czech Republic [Abstract]. European Health Psychology Society.
Agarwal N, Vogelzang NJ (2012). Beyond the abstract- Development of novel immune interventions for prostate cancer. [Review]. UroToday, UroToday.
Agarwal N, Vogelzang NJ (2012). Beyond the abstract- Development of novel immune interventions for prostate cancer. In UroToday. UroToday.com.
Ding YC, McGuffog L, Healey S, Friedman E, Laitman Y, Paluch-Shimon S, Kaufman B, SWE-BRCA, Liljegren A, Lindblom A, Olsson H, Kristoffersson U, Stenmark-Askmalm M, Melin B, Domchek SM, Nathanson KL, Rebbeck TR, Jakubowska A, Lubinski J, Jaworska K, Durda K, Gronwald J, Huzarski T, Cybulski C, Bryski T, Osorio A, Cajal TR, Stavropoulou AV, Benitez J, Hamann U, HEBON, Rookus M, Aalfs CM, de Lange JL, Meijers-Heijboer HE, Oosterwijk JC, van Asperen CJ, Gomez Garcia EB, Hoogerbrugge N, Jager A, van der Luijt RB, EMBRACE, Easton DF, Peock S, Frost D, Ellis SD, Platte R, Fineberg E, Evans DG, Lalloo F, Izatt L, Eeles R, Adlard J, Davidson R, Eccles D, Cole T, Cook J, Brewer C, Tischkowitz M, Godwin AK, Pathak H, GEMO Study Collaborators, Stoppa-Lyonnet D, Sinilnikova OM, Mazoyer S, Barjhoux L, Leone M, Gauthier-Villars M, Caux-Moncoutier V, de Pauw A, Hardouin A, Berthet P, Dreyfus H, Ferrer SF, Collonge-Rame MA, Sokolowska J, Buys SS, Daly M, Miron A, Terry MB, Chung W, John EM, Southey M, Goldgar D, Singer CF, Tea MK, Gschwantler-Kaulich D, Fink-Retter A, Hansen TV, Ejlertsen B, Johannsson OT, Offit K, Sarrel K, Gaudet MM, Vijai J, Robson M, Piedmonte MR, Andrews L, Cohn D, DeMars LR, DiSilvestro P, Rodriguez G, Toland AE, Montagna M, Agata S, Imyanitov E, Isaacs C, Janavicius R, Lazaro C, Blanco I, Ramus SJ, Sucheston L, Karlan BY, Gross J, Ganz PA, Beattie MS, Schmutzler RK, Wappenschmidt B, Meindl A, Arnold N, Niederacher D, Preisler-Adams S, Gadzicki D, Varon-Mateeva R, Deissler H, Gehrig A, Sutter C, Kast K, Nevanlinna H, Aittomaki K, Simard J, KConFab Investigators, Spurdle AB, Beesley J, Chen X, Tomlinson GE, Weitzel J, Garber JE, Olopade OI, Rubinstein WS, Tung N, Blum JL, Narod SA, Brummel S, Gillen DL, Lindor N, Fredericksen Z, Pankratz VS, Couch FJ, Radice P, Peterlongo P, Greene MH, Loud JT, Mai PL, Andrulis IL, Glendon G, Ozcelik H, OCGN, Gerdes AM, Thomassen M, Jensen UB, Skytte AB, Caligo MA, Lee A, Chenevix-Trench G, Antoniou AC, Neuhausen SL, Consortium of Investigators of Modifiers of BRCA12 CIMBA (2012). A non-synonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers.Epub 2012 June 22. Erratum In: Cancer Epidemiol Biomarkers Prev. 2012 Dec; 21(12):2278. PMID: 22729394. Cancer Epidemiol Biomarkers Prev, Aug;21(8), 1362-70.
Garrido-Laguna I, McGregor K, Wade M, et al (6/9/2012). Testing targeted demethylation to overcome resistance to epidermal growth factor receptor (EGFR) blocking agents in wild-type (wt) KRAS metastatic colorectal cancer patients (mCRC). 2012 ASCO Annual Meeting, Chicago, IL. (Abstract number 3057) [Abstract].
Heng DYC, Xie WL, Choueiri TK, Lee J, Harshman LC, Bjarnason GA, Knox JJ, MacKenzie M, Wood L, Vaishampayan UN, Yuasa T, Tan MH, Rha SY, Donskov F, Agarwal N, Kollmannsberger C, North S, Rini BI, and Choueiri TK (2012). An in-depth multicentered population-based analysis of outcomes of patients with metastatic renal cell carcinoma (mRCC) that do not meet eligibility criteria for clinical trials. Oral Presentation. 2012 Genitourinary Cancers Symposium. February 2-4, 2012, San Francisco, CA [Abstract]. J Clin Oncol 30, 2012 (suppl 5; abstr 353).
Agarwal N, Boucher KM, Maughan B, Hussain SA, Kaufman DS, LorussoV, Moore MJ, Galsky MD, Sonpavde G (2012). Pooled analysis of phase II trials evaluating weekly or conventional cisplatin as first-line therapy for advanced urothelial carcinoma. (Abstract #308). Poster Presentation. 2012 Genitourinary Cancers Symposium. February 2-4, 2012, San Francisco, CA [Abstract]. J Clin Oncol, 30(Suppl 5), abstr 308.
Heng DYC, ChoueiriTK, Lee JL, Harshman LC, Bjarnason G, Knox JJ, MacKenzie MJ, Vaishampayan UL, Tan MH, Rha SY, Donskov F, Agarwal N, Kollmannsberger CK, North, S, A, Rini BI, Wood L (2012). A multicentered population based analysis of outcomes of patients with metastatic renal cell carcinoma (mRCC) that do not meet eligibility criteria for clinical trials. (Abstract 353). Oral Presentation. 2012 Genitourinary Cancers Symposium. February 2-4, 2012, San Francisco, CA [Abstract]. J Clin Oncol 30, 2012.
Choueiri TK, Xie WL, Harshman LC, Bjarnason G, Knox JJ, MacKenzie MJ, Wood L, Vaishampayan UL, Tan MH, Rha SY, Donskov F, Agarwal N, Kollmannsberger CK, North SA, Rini BI, Heng DYC (2012). Conditional survival (CS) for patients with metastatic renal cell carcinoma (mRCC) treated with vascular endothelial growth factor (VEGF) targeted therapy (TT): Results from the international mRCC database consortium. Poster Presentation. 2012 Genitourinary Cancers Symposium. February 2-4, 2012, San Francisco, CA [Abstract]. J Clin Oncol, 30(suppl 5), abstr 358.
Heng DYC, Lee JL, Harshman LC, Bjarnason G, Razak AR, MacKenzie MJ, Wood L, Vaishampayan UI, Tan MH, Ran SY, Donskov F, Agarwal N, Kollmannsberger CK, North S, Rini BI, Choueiri TK, International mRCC Database Consortium (2012). A population-based overview of sequences of targeted therapy in metastatic renal cell carcinoma (mRCC). Poster Presentation. 2012 Genitourinary Cancers Symposium. February 2-4, 2012, San Francisco, CA. [Abstract]. J Clin Oncol 30, 2012 (suppl 5; abstr 387).
Smit WS, Sufliarsky J, Werner TL, Dizon D, Wagnerova M, Hirte HW, Spirtos N, Oza A, Dirix L, El-Hashimy M, Acharyya S, Tan EY, Weber D, Schellens JH (2012). A phase II study of Patupilone (EPO906) in patients with platinum- resistant or -refractory ovarian cancer. January 2012. [Abstract]. Clin Ovarian Cancer Other Gynecol Malig.
Goel S, Moran T, Coronado C, Ramirez SV, Chaudhary I, Ghalib MH, Swami U, Hou Y, Carcereny E, Alcantara J, Dios JLI, Miguel BD, Buges C, Rosell R (2012). Phase I dose-finding and pharmacokinetic study of a combination of elisidepsin (E) and erlotinib (T) in patients (pts) with advanced solid tumors [Abstract]. J Clin Oncol, 30(suppl; abstr 3093).
Fishman M, Hutson T, Agarwal N, Jonasch E (2012). Paradigm towards Tailored Therapies and Complete Responses in the Treatment of Metastatic Renal Cell Carcinoma. In Oncology & Hematology Review (8, pp. 30-8).
Poruk KE, Firpo MA, Boucher KM, Akerley WL, Neumayer LA, Sklow B, Scaife CL, Mulvihill SL (01/01/2012). Assessment of Serum Platelet Factor 4 as a Predictive Marker for VTE and as a Prognostic Biomarker in Pancreatic, Colorectal, Breast, and Lung Cancer. J Surg Res, 172(2), 242-243.
Fishman M, Hutson T, Agarwal N, Jonasch E (2012). Paradigm towards Tailored Therapies and Complete Responses in the Treatment of Metastatic Renal Cell Carcinoma. [Review]. Oncol Hematol Rev, 8(1): 30-8.
Hess D, Hagner N, Clive S, Gelderblom H, Rossmann E, Agarwal N, Grazia Porro M, Hengelage T, St-Pierre A, Gazi L, Li J, Woo MM, Sharma S (Nov 2011). Effects of Hepatic Funtion on the Pharmacokinetics and Safety of Panobinostate in Patients with Advanced Cancer: A Phase I Study. (ASH Annual Meeting Abstracts). [Abstract]. Blood, 118, 5007.
Sharma S, Voest E, Hagner N, Witteveen PO, Lolkema M, Agarwal N, Valera S, Li J, Mires D, Porro MG, Woo MM, and Hess D (Nov 2011). Effects of Renal Function on the Pharmacokinetics of Panobinostate in Patients with Advanced Cancer: A Phase I Study. [Abstract]. Blood, 118, 5001.
Cannon Albright LA, Teerlink C, Agarwal N, Stephenson R (2011). Evidence for a strong genetic contribution to lethal prostate cancer (Abstract-1205W). Poster Presentation International Congress of Human Genetics/ American Society of Human Genetics. October 11-15, 2011, Montreal, Quebec, Canada [Abstract].
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Dummer R, Garbe C, Testori A, Maio M, Hogg D, Lorigan P, Lebbe C, Jouary T, Schadendorf D, Ribas A, ODay SJ, Sosman JA, Kirkwood JM, Eggermont AM, Dreno B, Nolop K, Li J, Nelson B, Hou J, Lee RJ, Flaherty KT, McArthur GA, BRIM-3 Study Group, Akerley WL (2011 June 30). Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med, 2011 Jun(364(26):), 2507-16.
Patel SB, Gojo I, Tidwell M, Sausville EA, Baer MR (2011). Subdural hematomas in patients with Philadelphia chromosome positive acute lymphoblastic leukemia receiving imatinib mesylate in conjunction with systemic and intrathecal chemotherapy [Abstract]. Journal of Clinical Oncology, 29(15 suppl), abstr 6579.
Al-Marrawi MY, Rini BI, Harshman LC, Bjarnason GA, Wood L, Vaishampayan UL, MacKenzie MJ, Knox JJ, Agarwal N, Kollmannsberger CK, Tan MH, Rha SY, Donskov F, North S, Choueiri TK, Heng DYC (2011). The association of clinical outcome to front-line VEGF-targeted therapy with clinical outcome to second-line VEGF-targeted therapy in metastatic renal cell carcinoma (mRCC) patients (pts). Poster Presentation. American Society of Clinical Oncology (ASCO) Annual Meeting, Chicago, IL, June 3-7, 2011 [Abstract]. J Clin Oncol 29:2011 (suppl; abstr 5563.
Agarwal N, Sahu M, Abhyankar DJ, Werner TL, Benjamin B, Srinivas R, Sharma S (2011). A drug-drug interaction study of everolimus (a mTOR inhibitor) and JI-101, an orally active inhibitor of VEGF 2, PDGF and EphB4 receptors, in patients with advanced urologic tumors. American Society of Clinical Oncology (ASCO) Annual Meeting, Chicago, IL, June 3-7, 2011. [suppl; abstr e15077] [Abstract]. J Clin Oncol, 29(suppl), e15077.
Lam ET, Wong MKK, Agarwal N, Redman BG, Logan T, Flaig TW, Monk III JP, Jarkowski A, Sendilnathan A, Bolden M, Kuzel T, Olencki T (2011). Safety and efficacy of sequencing high-dose interleukin 2 (IL2) after tyrosine kinase inhibitor (TKI) therapy for metastatic renal cell carcinoma. [Abstract]. J Clin Oncol, 29(suppl), e15079.
Cohen, AL, Schabel M, Bild AH, Werner TL (2011). VAST (Valproic Acid Signature Trial): A proof-of-principle study correlating pharmacology, pathology, and advanced imaging with genomic prediction of drug sensitivity in breast cancer. Poster Presentation Oncology Annual Meeting, Chicago, Illinois, June 2011. (suppl; abstr TPS148) [Abstract]. J Clin Oncol, 29(15s).
Akerley W, Edwards S, Wilson R, Van Duren T, Akerley D, Tranter S, Sharry S (2011 June). Awareness of Radon - Associated Health Risks in Utah. Utah's Health: An Annual Review, 16(2011), 58-60.
Agarwal, N, Sahu M, Abhyankar J, Werner TL, Benjamin B, Srinivas NR, Sharma S (June 2011). A drug-drug interaction study of Everolimus (an mTOR inhibitor) and JI-101, an orally active inhibitor of VEGF2, PDGF, and EphB4 receptors, in patients with advanced urologic tumors. American Society of Clinical Oncology Annual Meeting, Chicago, Illinois, June 2011. Published in J Clin Oncol 29:15s, 2011 (suppl; abstr e15077). [Abstract]. Journal of Clinical Oncology, 29(15s).
Grossmann KF, Blankenship MB, Akerley W, Terrazas MC, Kosak KM, Boucher KM, Buys SS, Jones K, Werner TL, Agarwal N, Weis J, Sharma S, Ward JH, Shami PJ (2011). A phase I clinical study investigating disulfiram and copper gluconate in patients with advanced treatment-refractory solid tumors involving the liver [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; Abstract 1308 AACR. 2011 Apr 2-6; Orlando, Florida (FL): 2011. [Abstract].
Fury MG, Sherman EJ, Lisa DM, Agarwal N, Algazy KM, Brockstein B, Langer CJ, Lim D, Mehra R, Rajan SK, Jafri N, Korte S, Lipson B, Yunus F, Tanvetyanon T, Smith-Marrone S, Ng KK, Xiao H, Haque S, Pfister DG (05/23/2011). A randomized phase II study of cetuximab (C) every 2 weeks at either 500 or 750 mg/m2 for patients (Pts) with recurrent or metastatic (R/M) head and neck squamous cell cancer (HNSCC). Poster Presentation. American Society of Clinical Oncology (ASCO) Annual Meeting, Chicago, IL, June, 2011 [Abstract]. J Clin Oncol, 29(Suppl), abstr 5563.
Garrido-Laguna I, Janku F, Falchook GS, et al (2011). KRAS mutations in colorectal cancer may predict a pattern of organ-specific metastasis. AACR 102nd Annual Meeting, April 2-6, 2011; Orlando, FL. (Abstract # 2264) [Abstract].
Janku F, Garrido-Laguna I, Hong DS et al (2011). Loss of PTEN expression in patients treated with PI3K/AKT/mTOR signaling pathway inhibitors. AACR 102nd Annual Meeting 2011; April 2-6, 2011; Orlando, FL (Abstract #1279) [Abstract].
Garrido-Laguna I, Janku F, Falchook GS, Naing A, Fu S, Wheler J, Tsimberidou AM, Hong DS, Kurzrock R (Feb 2011). Retrospective study to elucidate a K-ras phenotype in patients with colorectal cancer.PMID: 27985389 [Abstract]. J Clin Oncol, 29(4_suppl), 462.
Zhang W, Winder T, Ning Y, Pohl A, Yang D, Kahn M, Lurje G, Labonte MJ, Wilson PM, Gordon MA, Hu-Lieskovan S, Mauro DJ, Langer C, Rowinsky EK, Lenz HJ (Jan 2011). A let-7 microRNA-binding site polymorphism in 3'-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapy. Ann Oncol, 22(1), 104-9.
Janku F, Garrido-Laguna I, Kurzrock R (2011). Early-Phase Cancer Clinical Trials: Are the Goals Scientific of Therapeutic? In Am Soc Clin Oncol Educ Book.
Swami U, Ghalib MH, Chaudhary I, Hou JY, Aparo S, Einstein MH, Goldberg GL, Elrafei TN, Gajavelli S, Cohen B, Rajdev L, Kaubisch A, Haigentz M, Mani S, Goel S (2011). Risks and Benefits of phase I trials: Twelve years experience from a single institution [Abstract]. J Clin Oncol, 29(suppl; abstr 6098).
Patel SB, Gojo I, Tidwell M, Ning Y, Zhao XF, Sausville EA, Baer MR (2011). Subdural hematomas in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia receiving imatinib mesylate in conjunction with multi-agent chemotherapy [Abstract]. Journal of Clinical Onocology, 29(suppl), abstr 6579.
Garrido-Laguna I, Kurzrock R, Falchook GS, et al (2011). Dual inhibition of VEGF pathway: Phase 1 trial of bevacizumab and cediranib in advanced solid tumors. 2011 ASCO Annual Meeting, Chicago, IL. (Abstract No: 3057) [Abstract].
Ohnuma T, Holland JF, Goel S, Wilck E, Lehrer D, Ghalib MH, Chaudhary I, Wilhelm F, Swami U, Mani S (2011). Final results of a Phase I dose-escalation study of ON01910.Na in combination with oxaliplatin in patients with advanced solid tumors [Abstract]. J Clin Oncol, 29(suppl; abstr e13584).
Janku F, Garrido-Laguna I, Tsimberidou A, et al (2011). Screening for PIK3CA Mutations, PTEN Loss and RAS/RAF mutations in Early-Phase Protocols with PI3K/mTOR Pathway Inhibitors. 2011 ASCO Annual Meeting, Chicago, IL. (Abstract No: 10507) [Abstract].
Agarwal N, Vogelzang NJ (2011). Development of novel immune interventions for genitor-urinary cancers. In Adrian Bot, Mihail Obrocea & Francesco Marincola (Eds.), Cancer Vaccines (1st Edition). London, UK: Informa Healthcare.
Winder T, Zhang W, Yang D, Ning Y, Bohanes PO, Hu-Lieskovan S, Mauro DJ, Langer C, Rowinsky EKLenz H (June 2010). Use of germ-line polymorphisms in genes involved in the IGF pathway to predict efficacy of cetuximab independent of K-ras in mCRC patients (IMCL-0144) [Abstract]. 28(15 Supplement), Abstract 3562.
Hu-LIeskovan S, Yang D, Grimminger PP, Arnold D, Dellas K, Machiels JH, Roedel C, Velenik V, Lenz H, Vallbohmer D (June 2010). Use of EGFa+61G and TS-5’UTR 2R/3R polymorphisms to predict complete pathologic response in locally advanced rectal cancer patients undergoing preoperative cetuximab-based chemoradiation followed by surgery [Abstract]. 28(15 Supplement), Abrtact 3641.
Alva AS, Agarwal N, Siefker-Radtke AO, Roth BJ, Smith DC, Daignault S, Srinivas S, Bradley DA, Hussain M (2010). Targeting epidermal growth factor receptor (EGFR) in urothelial cancer (UC): A phase II randomized trial of cisplatin (C) with gemcitabine (G) with or without cetuximab. Poster Presentation. American Society of Clinical Oncology (ASCO) Annual Meeting, Chicago, IL, June 4-8, 2010. [J Clin Oncol 28:7s, 2010 (suppl; abstr TPS239)] [Abstract]. J Clin Oncol 28:7s, 2010 (suppl; abstr TPS239).
Janku F, Tsimberidou A, Garrido-Laguna I et al (2010). Screening for PIK3CA, Ras and Raf mutations in trials with PI3K/Akt/mTOR signaling pathway inhibitors. 22nd EORTC-NCI-AACR symposium on "Molecular Targets and Cancer Therapeutics”, Berlin [Abstract].
Garrido-Laguna I, Janku F, Falchook GS, et al (2010). Clinical outcomes of patients with advanced head and neck tumors enrolled in phase I trials is not inferior to outcomes with last treatment line based on an FDA-approved drug. AACR 101st Annual Meeting, April 17-21, 2010, Washington, DC. (Abst #2773) [Abstract].
Swami U, Petrylak DP, Raftopoulos H, Shuster DE, Wang G, Kumar V, Martinez G, Goel S, Aisner J (2010). Phase IB study of eribulin mesylate in combination with carboplatin in patients with advanced solid tumors [Abstract]. J Clin Oncol, 28:15s(suppl; abstr 2589).
Chaudhary I, Rajdev L, Swami U, Wilhelm F, Cohen B, Haigentz M, Kaubisch A, Goel S, Mani S, Ghalib MH (2010). Phase I dose-escalation study of ON 01910.Na in combination with oxaliplatin in patients with advanced solid tumors [Abstract]. J Clin Oncol, 28(suppl; abstr e13133).
Colonna SV, Douglas Case L, Lawrence JA (2009). Correlation of the Metabolic Syndrome with Estrogen Receptor Negative Breast Cancer in a Retrospective Review [Abstract].
Kurzrock R, Wheler J, Hong DS, Guo Z, Mulcahy MF, Benson III AB, Goel S, Swami U, Mani S, Buchbinder A (2009). Phase I, first in human dose escalation study of EZN-2208, a novel anticancer agent, in patients with advanced malignancies [Abstract].
Bild AH, Sun Y, Soldi R, Conner T, Walker D, Werner T, Spira A, Andrulis I, Buys SS, Johnson E (2009). A Genomic Biomarker for Breast Cancer Development in High-Risk Women. Poster Presentation. CTRC-AACR San Antonio Breast Cancer Symposium, San Antonio, Texas, December 2009. Published in Cancer Res 2009; 69(Suppl.): (24). Dec 15, 2009. [Abstract]. Cancer Res, 69(24).
Agarwal N, Gordeuk VR, Prchal JT (2009). Genetic Mechanisms Underlying Regulation of Hemoglobin Mass. In Roach RC, Wagner PD, and Hackett PH (Eds.), Hypoxia and Circulation (2007, pp. 195-210). New York: Springer.
Agarwal N, Rodgers GM (2009). Miscellaneous Causes of Thrombocytopenia. In Greer JP, Foerster J, Rodgers GM et al. (Eds.), Wintrobe's Clinical Hematology (Edition 12, 2, pp. 1326-1334). Lippincott Williams & Wilkins.
Tan A, Jimeno A, Garrido-Laguna I, Uson M, De Oliveira E, Wilson A, Rubio-Viqueira B, Rajeshkumar NV, Hidalgo M (May 2009). Use of amolecular mimicry approach to identify effective agents in pancreatic cancer.PMID: 27964150 [Abstract]. J Clin Oncol, 27(15_suppl), 4603.
Garrido-Laguna I, Rudek M, Tan A, Uson M, Iacobuzio-Donahue C, Angenendt M, Jimeno A, Laheru D, Barret M, Hidalgo M (May 2009). Preclinical identification of biomarkers of response to mTOR inhibitors and subsequent application in a phase II trial of sirolimus in pancreatic cancer patients refractory to gemcitabine.PMID: 27964189 [Abstract]. J Clin Oncol, 27(15_suppl), 4612.
Hidalgo M, Garrido-Laguna I, Uson M, De Oliveira E, Schulick R, Hruban RH, Maitra A, Jimeno A, Rubio-Viqueira B, Rajeshkumar NV (May 2009). Activity of gemcitabine in direct patient-derived xenografts and clinical outcome: Validation of an in vivo model for drug development.PMID: 27962716 [Abstract]. J Clin Oncol, 27(15_suppl), 4528.
Lim HY, Werner TL, Agarwal N, Rodgers GM (2008). Management of Thrombotic Microangiopathy with Underlying Malignancy. Review Series - Oncology, 12(2), 18-21.
Smit WM, Sufliarksy J, Werner TL, Dizon D, Wagnerova M, Hirte HW, Delaney R, Li J, Weber D, Schellens JH (2009). A phase II study evaluating the safety and efficacy of Patupilone in patients with platinum refractory/resistant ovarian, primary fallopian, or peritoneal cancer. Poster Presentation. American Society of Clinical Oncology Annual Meeting, Orlando, Florida, May 2009. Published in J Clin Oncol 27:15s, 2009 (suppl; abstr 5563). [Abstract]. Journal of Clinical Oncology, 27(15s), 5563.
Janku F, Garrido-Laguna I, Hong D, Tsimberidou A, et al (2009). PIK3CA mutations in patients with advanced cancers treated in phase I clinical trials. AACR-NCI-EORTC Molecular Targets in Cancer Therapeutics (Abst. B134). Boston [Abstract].
Villaroel MC, Tan AC, Garrido-Laguna I, Rubio-Viqueira B, De Oliveira E, Rajeshkumar NV, Jimeno A, Hidalgo M (2009). Orthotopic cancer models are better predictors of clinical response than s.c. models. AACR 100th Annual Meeting in Denver (Permanent abst number 2320). [Abstract].
Rajeshkumar NV, De Oliveira E, Ottenhof N, Garrido-LagunaI I, et al (2009). MK-1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions in pancreatic tumor xenografts. AACR-NCI-EORTC Molecular Targets in Cancer Therapeutics (Abst. A251). Boston [Abstract].
Maitra A, Rajeskhumar NV, Rudek M, Garrido-Laguna I, Laheru D, Iglesias J, Desai N, Von Hoff D, Hidalgo M (2009). Nab-paclitaxel targets tumor stroma and results, combined with gemcitabine, in high efficacy against pancreatic models. C246. AACR-NCI-EORTC Molecular Targets in Cancer Therapeutics (Abst. C246). Boston [Abstract].
Garrido-Laguna I (2009). Targeted Therapies. In Ettinger DS, Donehower RC, Olsen M, Schwartz RN (Eds.), Current Cancer Therapeutics, Springer Editorial (5th).
Mishra A, Feldmann G, Garrido-Laguna I, Dadon T, Strock C, Bannerji R, Hidalgo M, Maitra A, Nelkin B (2009). SCH727965, a novel potent cyclin dependent kinase inhibitor, inhibits pancreatic tumor growth and Ras-mediated tumorigenic signaling. AACR-NCI-EORTC Molecular Targets in Cancer Therapeutics (Abst. A243). Boston [Abstract].
Garrido-Laguna I, Tan AC, Villarroel MC, Angenendt M, Pastori W, Rajeshkumar NV, Ciomei M, Jimeno A, Rubio-Viqueira B, Hidalgo M (2009). Activity of PHA-848125 in pancreatic cancer xenografts is related to downregulation of S6 via p53 pathway. AACR 100th Annual Meeting in Denver (Permanent abst number 1798). [Abstract].
Agarwal N, Prchal JT (2009). Dyshemoglobinemia. In Steinberg MH, Forget BG, Higgs DR, Nagel RL (Eds.), Disorders of Hemoglobin, Genetics, Pathophysiology, and Clinical Management (2nd ed, pp. 607-622). New York: Cambridge University Press.
Kurzrock R, Wheler J, Hong DS, Guo Z, Mulcahy MF, Benson III AB, Goel S, Swami U, Mani S, Buchbinder A (2009). Phase I, first in human dose escalation study of EZN- 2208, a novel anticancer agent, in patients with advanced malignancies [Abstract]. Mol Cancer Ther, 8(12 suppl), C216.
Hidalgo M, Strawn S, Wick M, Rajeshkumar NV, Garrido-Laguna I, Sidranski D, Bruckheimer E (2009). From mice to men: Guiding cancer treatment through Personalized Tumorgraft models results in prolongued clinical responses in patients with refractory advanced cancers and discovery of novel predictive biomarkers. AACR-NCI-EORTC Molecular Targets in Cancer Therapeutics (Abst. A19). Boston [Abstract].
Agarwal N, Prchal JT (2009). Methemoglobinemia and Other Dyshemoglobinemias. In Kaushansky K, Lichtman M, Beutler E, et al. (Eds.), Williams Hematology (8th edition). New York: McGraw-Hill.
Lim HY, Werner TL, Agarwal N, Rodgers GM (2008). Management of Thrombotic Microangiopathy with Underlying Malignancy. In Review Series Oncology (12, pp. 18-21).
Agarwal N, Swierczek S, Naidoo K, Prchal JT, Coetzer TL (2007). A novel Mutation of the aSpectrin Gene in a Family of Northern European Descent is Associated with Three Different Phenotypes. [Abstract]. Blood. 2007; 110 (11): abstract 1717.
Agarwal, N, Swierczek S, Rothstein G, Nussenzveig R, Prchal J (2007). Is Hematopoiesis Clonal in Healthy Elderly Females? [Abstract]. Blood, 2007; 110 (11): abstract 2243, 110(11), abstract 2243.
Spahr JE, Agarwal N, Rodgers GM (2007). Treatment of Immune-Mediated Thrombocytopenia Purpura with Concurrent IVIg and Platelet Transfusion: A Retrospective Review of 40 Patients. [Abstract]. Blood "Supplement", 108(11), A1598.
Agarwal AM, Agarwal N, Tryka AF, Ward JH, Lim MS (2007). Blastic Transformation of Follicular lymphoma. [Abstract]. Archives of Pathology and Laboratory Medicine (supplement), September 2007.
Horvath LE, Werner T, Jones K (2007). The Relationship between Tumor Size and Stage in Early versus Advanced Ovarian Cancer: A Retrospective Chart Review. Poster Presentation. American Society of Clinical Oncology Annual Meeting, Chicago, Illinois, June 2007. Published in J Clin Oncol, 25:18s, 2007 (suppl; abstr 5580). [Abstract]. Journal Of Clinical Oncology, 25(18s), 5580.
Agarwal N, Gordeuk VR, Prchal JT (2007). Genetic Mechanisms Underlying Regulation of Hemoglobin Mass. In Roach RC, Wagner PD, and Hackett PH (Eds.), Hypoxia and Circulation. New York: Springer.
Agarwal N, Mojica-Henshaw MP, Kutlar F, Gaikwad A, Ou CN, Kutlar A, Prchal JT (2006). Novel Mechanism of β0 Thalassemia: Missense Mutation of the Last Nucleotide of β Globin Exon 1 (G->C) Leads to Undetectable Transcript and Mutant Peptide. [Abstract]. Blood (supplement), 2006; 108: A1598.
Wada D, Agarwal N, Florell SR, Lim M (2006). Recurrent Squamous cell carcinoma and fallicular lymphoma arising in the scalp two years after treatment for lymphoma. [Abstract]. Arch Pathol Lab Med, 130, 1362-1403 (P14).
Garrido-Laguna I (2006). Emergencies in Oncology. In Manual de Diagnostico y Terapeutica Medica Hospital Universitario 12 de Octubre, (Manual of Emergency University Hospital 12 de Octubre) (6th). MSD Editorial.
Wada D, Agarwal N, Lim M (2005). Case of the Quarter: Society of Hematopathology [Web]. Society for Hematopathology. Available: http://www.sh-eahp.org/.
Hu-Lieskovan S, Heidel JD, Bartlett DW, Davis ME, Triche TJ (Oct 2005). Sequence-specific knockdown of EWS-FLI1 by targeted, non-viral delivery of siRNA inhibits tumor growth in a murine model of metastatic Ewing’s sarcoma. Cancer Res, 65(19), 8984-8992.
Popielarski SR, Hu-Lieskovan S, French SW, Triche TJ, Davis ME (Aug 2005). A nanoparticle-based model delivery system to guide the rational design of gene delivery to the liver. 2. In vitro and in vivo uptake results. Bioconjug Chem, 16(5), 1071-80.
Schluep T, Jensen GS, Chen J, Heidel JD, Bartlett DW, Hu S, Triche TJ, Davis ME (June 2005). Camptothecin-polymer conjugate shows improved biodistribution and preclinical efficacy in vivo [Abstract]. 46(9 Supplement), 328.
Hu-Lieskovan S, Zhang J, Schofield DE, Shimada H, Wu L, Triche TJ (Jun 2005). EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing’s family of tumors. Cancer Res, 65(11), 4633-44.
Hu S, Zhang J, Liu X-F, Schofield D, Triche T (June 2005). EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed molecular phenotype of Ewing’s family of tumors [Abstract]. 65(9 Supplement), 4633-4644.
Heidel JD, Hu-Lieskvoan S, Bartlett DW, Triche TJ, Davis ME (May 2005). Systemic Administration of siRNA Against EWS-FLI1 Using a Targeted, Non-Viral Formulation Inhibits Growth in a Disseminated Murine Model of Ewing's Sarcoma [Abstract]. 11(Supplement 1), S28-S29.
Hu S, H JD, B DW, K DB, D ME, T TJ (May 2005). Systemic targeted EWS-FLI1 siRNA abrogates growth of metastases in a murine Ewing’s tumor model [Abstract]. 65(9 Supplement), 1435-1436.
Zhang J, Hu S, Schofield D, Sorensen P, Triche TJ (Sep 2004). Selective usage of D type cyclins by Ewing's tumors and rhabdomyosarcomas. Oncogene, 64(17), 6026-34.
Hussain I, Agarwal N (2003). DRESS syndrome associated with cephalosporin therapy [Web]. E-Letter in British Medical Journal. Available: https://goo.gl/NIq711.
Akerley W, Herndon J, Green M, et al (2003). Dose-Dense Weekly Paclitaxel and Pharmacologic Evaluation for Patients with Stage IIIB-IV Non-Small Cell Lung Cancer: A Phase II Trial of Cancer and Leukemia Group B (CALGB 9731/9765). Cancer, 97, 2480-6.
Gupta S (2002). Retrospective study on the effect of chronic ACE inhibitor therapy on inter-dialysis weight gain in patients on hemodialysis [Abstract]. Ren Fail, Jul;24(4), 461-6.
Makarovskiy A, Siryaporn E, Hixon D, Akerley W (2002). Survival of Docetaxel-resistant Prostate Cancer Cells Depends on Phenotype Alterations and Continuity of Drug Exposure. Cell Mol Life Sci, 59, 1198-1211.
Akerley W, Butera J, Wehbe T, Noto R, Stein B, Safran H, Cummings F, Sambandam S, Maynard J, Di Rienzo G, Leone L (2002). A Multiinstitutional, Concurrent Chemoradiation Trial of Strontium-89, Estramustine, and Vinblastine for Hormone Refractory Prostate Carcinoma Involving Bone. Cancer, 94(6), 1654-1660.
Blackstock A, Herndon J, Paskett E, Perry M, Graziano S, Muscato, Kosty M, Akerley W, Holland J, Fleishman S, Green M (2002). Outcomes Among African-American and Non African-American Patients with Advanced Non-Small Cell Lung Cancer: A Report from the CALGB. J Natl Cancer Inst, 94(4), 284-90.
Akerley W, Rathore R, Ready N, Leone L, Sikov W, Safran H, Kennedy T (2002). A phase I study of a weekly schedule of paclitaxel and carboplatin in patients with advanced carcinoma. Cancer, 95(9), 2000-5.
Akerley W (2001). Recent Development in Weekly Paclitaxel Therapy of Lung Cancer. Curr Oncol Rep, 3(2), 165-169.
Gurevich I, Akerley W (2001). Treatment of the Jaundiced Patient with Breast Carcinoma. Cancer, 91(4), 660-663.
Wanebo H, Chougule P, Ready N, Safran H, Akerley W, Koness R, McRae R, Nigri P, Leone L, Kennedy T, Webber B (2001). Surgical Resection is Necessary to Maximize Tumor Control In Function Preserving, Aggressive Chemoradiation Protocols for Advanced Squamous Cancer of the Head and Neck (Stage III and IV). Ann Surg Oncol, 8, 644-50.
Savarese DM, Halabi S, Hars V, Akerley WL, Taplin ME, Godley PA, Hussain A, Small EJ, Vogelzang NJ (2001). Phase II Study of Docetaxel, Estramustine, and Low-dose Hydrocortisone in Men with Hormone-refractory Prostate Cancer: a final report of CALGB 9780. J Clin Oncol, 19(9), 2509-16.
Stults BM, Dunson WA, Young D (2001). Management of Hypertension in Diabetes Mellitus. Utah Diabetes Association Review.
Wang H, Hu S, Zhang J (Jul 2000). Expression of T cell receptor Va gene families in intrathyroidal T cells of Chinese patients with Graves’ disease (in English)Expression of T cell receptor Va gene families in intrathyroidal T cells of Chinese patients with Graves’ disease (in English). Chin Med Sci J, 15(3), 175-9.
Dupuy D, Zagoria R, Akerley W, Mayo-Smith W, Kavanagh P, Safran H (2000). Percutaneous Radiofrequency Ablation of Malignancies in the Lung. Am J Roentgenol Radium Ther Nucl Med, 174(1), 57-9.
Akerley W (2000). Secondary Leukemia: Twice is a Coincidence? Cancer, 88(3), 497-9.
King T, Akerley W, Fan A, Walsh K, Mangray S, Chen M, Safran H (2000). P53 Mutations Do Not Predict Response to Paclitaxel for Metastatic Non-Small Cell Lung Cancer. Cancer, 89(4), 769-73.
Akerley W (2000). Paclitaxel in Advanced Non-small Cell Lung Cancer: An Alternative High-dose Weekly Schedule. Chest, 117:4 (suppl 1), 152-5.
Akerley W and Choy H (1999). Single Agent Paclitaxel and Radiation for Non-Small Cell Lung Cancer. Semin Radiat Oncol, 9(2) suppl 1, 85-89.
Wanebo H, Chougule P, Ready N, Koness R, Akerley W, McRae R, Nigri P, Leone L, Webber B, Safran H (1999). Preoperative Paclitaxel, Carboplatin and Radiation Therapy in Advanced Head and Neck Cancer. Semin Radiat Oncol, 9(2) suppl 1, 77-84.
Chougule P, Akhtar M, Akerley W, Ready N, Safran H, McRae R, Nigri P, Bellino J, Koness R, Radie-Kane K, and Wanebo H (1999). Chemoradiotherapy for Advanced Inoperable Head and Neck Cancer: A Phase II Study. Semin Radiat Oncol, 9(2) suppl 1, 58-63.
Glantz M, Kim L, Choy H, Akerley W (1999). Concurrent Chemotherapy and Radiotherapy in Patients with Brain Tumors. Oncology, 13(10) suppl 5, 78-82.
Choy H, Akerley W, Safran H, Graziano S (1997). Concurrent Weekly Paclitaxel and Radiation Therapy for Locally Advanced NSCLC. Lung Cancer, 18(S2), 152.
Choy H, King T, Akerley W, Safran H (1997). Paclitaxel and Concurrent Radiation for Lung, Pancreatic and Gastric Carcinomas: Significance of p53 Gene Mutations for Treatment Response. Semin Radiat Oncol, 7(3), s77-81.
Choy H, Akerley W, Devore R (1997). Paclitaxel in Combined Modality Therapy for Locally Advanced Non-Small Cell Lung Cancer. Advances in Oncology, 13(4), 17-24.
Makarovskiy A, Ackerley W, Wojcik W, Halpert G, Stein B, Carreiro M, Hixson D (1997). Application of Immunomagnetic Beads in Combination with RT-PCR for the Detection of Circulating Prostate Cancer Cells. J Clin Lab Anal, 11, 346-50.
Choy H, Akerley W, Safran H, Clark J, Rege V, Papa A, Glantz M, Puthawala Y, Soderberg C, Leone L (1997). Phase I Trial of Outpatient Weekly Paclitaxel and Concurrent Radiation Therapy for Advanced Non-Small Cell Lung Cancer. Classic Papers and Current Comments, 2(1), 167-71.
Glantz M, Choy H, Akerley W, Kearns C, Egorin M, Rhodes H, Cole B (1996). Weekly Paclitaxel With and Without Concurrent Radiation Therapy: Toxicity, Pharmacokinetics and Response. Semin Oncol, 23(6) Suppl 16, 128-135.
Akerley W, Glantz M, Choy H (1996). Phase I Study of Weekly Outpatient Paclitaxel in Advanced and Metastatic Non-small Cell Lung Cancer. Semin Oncol, 23(5), Suppl 12, 14-18.