Celiac IgA Panel

Ordering Recommendation

•This is an autoantibody panel for initial diagnostic assessment and disease monitoring in celiac disease that may be associated with skin disease.

• Use for disease monitoring with semiquantitative antibody level assessments and tracking.

•To test for dermatitis herpetiformis associated with celiac disease, order the Dermatitis Herpetiformis IgA Panel instead with perilesional skin biopsy for direct immunofluorescence.

Components

• IgA endomysial (EMA) antibodies by indirect immunofluorescence
• IgA tissue transglutaminase (transglutaminase type 2, TG2) antibody level by ELISA

Methodology

Indirect immunofluorescence/enzyme-linked immunosorbent assay (ELISA)

Performed

Varies

Reported

4-9 days

New York Department of Health (NYDOH) Approval Status

This test is New York DOH approved.

Information Required to Submit with Order

Completed Immunodermatology Laboratory requisition form and copies of both sides of insurance cards or completed billing information

CPT Code(s)

88346; 83516 x 1 (86256 x 1 possible)
 

SPECIMEN REQUIREMENTS

Collect Blood

Plain red top tube or serum separator tube.  

Specimen Preparation

2 mL serum separated from blood into serum vial provided in kit (Minimum needed: 0.5 mL) 

Storage/Transport Temperature

Room temperature  

Conditions with Disclaimer for Potentially Anomalous Results

Hemolyzed or lipemic serum specimens, whole blood  

Stability

Ambient: 7 days
Refrigerated: 14 days
Frozen: Indefinitely