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Immunodermatology Laboratory

Immunodermatology Laboratory

The Immunodermatology Laboratory at the University of Utah, with its team including board-certified Immunodermatologists, is committed to providing reliable, rapid, and comprehensive testing for diagnosis and disease monitoring. We welcome all requests from physicians seeking immunodermatology testing.

Immunodermatology testing is essential for the correct diagnosis and treatment of many diseases affecting epithelial organs including skin and oral, genital, and ocular mucous membranes, gastrointestinal and respiratory tracts. Tests are performed on blood and tissues that are sent to our laboratory from medical facilities and referring physicians across the United States.

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Why Immunodermatology at the University of Utah

Experts in the Field with 25 Years of Experience

 The Laboratory team is comprised of industry recognized experts.  Drs. John J Zone and Kristin Leiferman, who have individually create benchmarks within the industry,  lead teams that are comprised of equally accomplished individuals.  Learn more about Drs. Mazdak Khaligi, Margaret Cocks and Melanie Kuechle


Academic Institution

The University of Utah Health's School of Medicine combines excellence in teaching, research, and clinical expertise to train tomorrow's physicians for the rapidly changing world of medicine. With a faculty of more than 1,000 physicians and researchers and 23 clinical and basic science departments.  The UHealth School of Medicine is amongst the Nation's Best.

School of Medicine's Latest News

University of Utah

Electronic Medical Records (EMR) Interfacing

The Laboratory Services team uses an EMR system to reduce paper and increase efficiency for our clients. This also enables us to maintain accurate records that are easily accessible for referral reporting or linking to historical cases.   Our goal is to make it as easy as possible for your team to interface with ours so that we become an accessory to your practice.

UHealth's EMR


    Broadly speaking, immunodermatology is part of the whole understanding of the human integument, including skin, mucous membranes, hair, and nails, that is related to immunology and covers clinical disease as well as laboratory testing. Laboratory Immunodermatology is a key component of comprehensive dermatology care. Testing in the Immunodermatology Laboratory aids in the diagnosis and monitoring of several immunological diseases with cutaneous involvement.

    Immunodermatology testing importantly aids in the diagnosis of several diseases. In addition, the testing results are useful in assessing disease expression and following disease activity. Increasingly, the testing is recognized as helpful even in common conditions such as itching and eczema. The range of clinical findings that immune-mediated diseases present with is large, often with overlapping features. Immunodermatology test results are beneficial for sorting out the etiology and, therefore, directing treatments.

    Testing in the Immunodermatology Laboratory aids in the diagnosis of several immunological diseases with skin and mucous membrane involvement. The testing is helpful, not only in in establishing diagnoses, but also determining treatments and monitoring response to treatment. Diagnosis of immunobullous diseases is particularly aided when both serum and skin/mucous membrane biopsy specimens are tested by indirect immunofluorescence and by direct immunofluorescence, respectively, because indirect immunofluorescence and ELISA results on serum will classify disease subtypes based on the very sensitive DIF findings. Furthermore, many immune-mediated diseases have overlapping clinical features, and the testing is helpful in distinguishing the disorders. Also, immune-mediated diseases may present with secondary features or with features of common conditions, and the testing is helpful to determine the etiology. As the population ages with more tendency to develop immune-mediated diseases and as immunologically mediated disease are better defined, the testing becomes ever more important in patient care.

    Immunodermatology testing is used in the evaluation of all types of pemphigus and pemphigoid, including pemphigoid gestationis, linear IgA disease (linear IgA bullous dermatosis and bullous disease of childhood), epidermolysis bullosa acquisita, dermatitis herpetiformis, most types of lupus erythematosus, vasculitis including IgA vasculitis (Henoch Schönlein purpura), lichen planus and other lichenoid reactions. It is helpful in evaluating urticaria, drug reactions, other connective tissue diseases, porphyria and pseudoporphyria. It is helpful in celiac disease and other intestinal disorders.