Publications

Selected Publications

• Reig T, Kohan DE. Regulation of nephron water and electrolyte transport by adenylyl cyclases. Am J Physiol 306:F701-F709, 2014.
• Kohan DE, Barton M. Endothelin and endothelin antagonists in chronic kidney disease. Kidney Int 86:896-904, 2014.
• Rees S, Kittikulsuth W, Roos K, Strait KA, van Hoek A, Kohan DE. Adenylyl cyclase 6 deficiency markedly ameliorates polycystic kidney disease. J Am Soc Nephrol 25:232-237, 2014.
• Kohan DE, Fioretto P, Tang W, List JF. Long-term randomized study of dapagliflozin in patients with type 2 diabetes and moderate renal impairment who have inadequate glycemic control. Kidney Int 85:962-971, 2014.
• de Zeeuw D, Coll B, Andress D, Brennan JJ, Tang H, Houser M, Correa-Rotter R, Kohan D, Lambers Heerspink HJ, Makino H, Perkovic V, Pritchett Y, Remuzzi G, Tobe S, Viberti G, Parving H-H. The endothelin antagonist atrasentan lowers residual albuminuria in type 2 diabetic patients with nephropathy. J Am Soc Nephrol 25:1083-1093, 2014.
• Ramkumar N, Stuart D, Rees S, Van Hoek A, Sigmund C, Kohan DE. Collecting duct specific deletion of renin attenuates angiotensin-II infused hypertension. Am J Physiol 307:F931-F938, 2014.
• Pandit MM, Inscho EW, Seki T, Rohatgi R, Gusella L, Zhou J, Zhang S, Kishore BK, Kohan DE. Flow regulation of endothelin-1 production in the inner medullary collecting duct. Am J Physiol 308:F541-F552, 2015.
• Ramkumar N, Stuart D, Calquin M, Quadri S, Wang S, Van Hoek A, Siragy H, Ichihara A, Kohan DE. Nephron specific deletion of the prorenin receptor causes a urine concentration defect. Am J Physiol 309:F48-F56, 2015.
• Kohan DE, Lambers Heerspink HJ, Coll B, Andress D, Brennan JJ, Kitzman DW, Correa-Rotter R, Makino H, Perkovic V, Hou FF, Remuzzi G, Tobe SW, Toto R, Parving H-H, de Zeeuw D. Predictors of atrasentan-associated fluid retention and change in albuminuria in patients with diabetic nephropathy. Clin J Am Soc Nephrol 10:1568-1574, 2015.
• Pearce D, Soundararajan R, Trimpert C, Kashlan OB, Deen PMT, Kohan DE. Collecting duct principal cell transport processes and their regulation. Clin J Am Soc Nephrol 10:135-146, 2015.
• Kohan DE. Introduction and basic biology of the renal endothelin system. Semin Nephrol 35:121-124, 2015.
• Ramkumar N, Kohan DE. The nephron (pro)renin receptor: function and significance. Am J Physiol 311:F1145-F1148, 2016.
• Kohan DE, Fioretto P, Johnson K, Parmik S, Ptaszynska A, Sugg J, Ying L. The effect of dapagliflozin on renal function in patients with type 2 diabetes. J Nephrol 29:391-400, 2016.
• Ramkumar N, Stuart D, Mironova E, Bugay V, Wang S, Ichihara A, Stockand JD, Kohan DE. Renal tubular epithelial cell prorenin receptor regulates blood pressure and sodium excretion. Am J Physiol 311:F186-F194, 2016.
• Gao Y, Stuart D, Pollock JS, Takahishi T, Kohan DE. Collecting duct-specific knockout of nitric oxide synthase 3 impairs water excretion in a sex-dependent manner. Am J Physiol 311:F1074-F1083, 2016.
• Poulsen SB, Kristensen TB, Brooks, HL, Kohan DE, Rieg T, Fenton RA. Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus. J Clin Invest Insight 2:e91042, 2017.
• Wheatley W, Kohan DE. Role for reactive oxygen species in flow stimulated inner medullary collecting duct endothelin-1 production. Am J Physiol 313:F514-F521, 2017.
• Gao Y, Stuart D, Takahashi T, Kohan DE. Nephron-specific deletion of nitric oxide synthase 3 causes hypertension and impaired salt excretion. J Am Heart Assoc 7:e009236, 2018.
• Ramkumar N, Stuart D, Mironova E, Abraham N, Gao Y, Wang S, Ichihara A, Genzen JR, Stockand JD, Kohan DE.. Collecting duct principal cell prorenin receptor mediates prorenin-stimulated epithelial sodium channel activity. Am J Physiol (in press).

Note: For a more complete list of publications, please visit Dr. Kohan's PubMed page.