Research Interests
Inspired by my background as an exercise physiologist and a competitive swimmer, my research interests include neural and humoral determinants for the development of muscle fatigue, in particular the respiratory muscles, and the control of breathing during exercise. My current research focus is on the actions and interactions of chemoreflex, baroreflex, and metaboreflex regarding the regulation of cardiorespiratory responses to exercise in healthy and disease states.
Education
- PhD, Kinesiology, Kansas State University, Manhattan, KS
- MS, Kinesiology, Kansas State University, Manhattan, KS
- BS, Kinesiology, Washburn University, Topeka, KS
Research Interests
I am interested in how the central and peripheral components of the cardiovascular system interact with peripheral metabolic pathways to establish adequate oxygen delivery to tissues. Specifically, how local factors such as reactive oxygen species and nitric oxide impact ‘upstream’ delivery and ‘downstream’ usage of oxygen in skeletal muscle/mitochondria in health and disease. The goal of my research is to gain a greater understanding of the mechanisms which contribute to dysfunction at the interface of the vascular and skeletal muscle systems.
Education
- PhD, Human and Exercise Physiology, University of Calgary, Canada
- MS, Exercise Physiology, University of Rome, Italy
- BS, Sport Sciences, University of Cassino and Southern Lazio, Italy
Research Interests
I am interested in exploring how the metabolic, cardiovascular, and neuromuscular systems integrate at rest, during exercise, and in response to conditions that challenge O2 delivery to the exercising muscles in health and disease. The overarching goals of my research are to i) pinpoint the mechanisms that at various levels of these control systems limit exercise tolerance and ii) find novel, population-specific exercise-based interventions that mitigate the deleterious effects of physical inactivity, aging, and chronic disease. Currently, the focus of my research is to further our understanding of the mechanisms responsible for exercise intolerance in heart failure patients and of the potential beneficial effects of localized locomotor muscles training in this population.
Education
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PhD, Neuroscience, Biomedicine and Movement, University of Verona, Verona, Italy
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BS, Sport Sciences, University of Insubria, Varese, Italy
Research Interests
My research interests are centered around the study of the mechanistic basis of fatigue by integrating circulatory, respiratory, metabolic, and neuromuscular responses in exercising humans. During my doctoral training, I focused on parsing out the role of central motor command from reflex-mediated responses on exercise performance and autonomic adjustments. Currently, my research goal is to advance our understanding of neurally-mediated cardiovascular adjustments in health and disease, with a particular focus on the neural control of circulation in chronic pain patients.
Education
- PhD, Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT
- MS, Health and Exercise Science, Colorado State University, Fort Collins, CO
- BS, Exercise and Sport Science, Western State Colorado University, Gunnison, CO
Research Interests
My research interests broadly include exercise physiology and neural regulation of the peripheral circulation. More specifically, I am interested in how the autonomic nervous system regulates the cardiovascular system in various situations, and in different populations. My doctoral studies focused on elucidating the mechanisms within the sympathetic nervous system that are dysregulated in the context of heart failure, and how they contribute to the pathophysiology of this syndrome, particularly regarding exercise intolerance. Currently, I am pursuing investigations that focus on the physiological underpinnings of the elevated risk of developing cardiovascular disease in Veterans with PTSD, which may be related to autonomic disturbances accompanying this syndrome.
Education
- PhD, Kinesiology, Auburn University, Auburn, AL
- MS, Kinesiology, Auburn University, Auburn, AL
- BS, Exercise Science, University of Montana, Missoula, MT
Research Interests
My research is focused on exercise and muscle physiology with an emphasis on the molecular adaptations to exercise and aging.
Education
- PhD, Human Bioenergetics, Ball State University, Muncie, IN
- MS, Clinical Exercise Physiology, Ball State University, Muncie, IN
- BS, Exercise Science, Salisbury University, Salisbury MD
- BS, Public Health, Salisbury University, Salisbury MD
Research Interests
My research interests are broadly focused on determining novel lifestyle interventions (i.e., supplementation/pharmacological, exercise) in the prevention and treatment of age and disease-related vascular and metabolic dysfunction from a clinically translatable approach.
During my doctoral training, my work focused on determining novel nutraceutical supplementation strategies to combat age-related arterial stiffening, examining the influence of aortic perivascular adipose tissue in humans on arterial stiffening and cardiovascular hemodynamics, and identifying the underlying role of mitochondrial-derived oxidative stress as a primary mechanism contributing to impaired vascular endothelial function in older adults with lower cardiorespiratory fitness.
Currently, my research involves identifying mechanisms regulating redox balance and metabolic homeostasis that limit improvements in cardiovascular function from physical inactivity, aging and disease at rest and during exercise.
nicholas.carlini@hsc.utah.edu
Education
- PhD, Rehabilitation Science; Carver College of Medicine, University of Iowa, IA
- MS, Exercise Science, Brigham Young University, UT
- BS, Exercise Physiology, Brigham Young University-Idaho, ID
Research Interests
My research focuses on vascular endothelial function and cardiovascular adaptations under the broad spectrum of exercise physiology. Within this umbrella of cardiovascular physiology, my interests are primarily focused on how alterations in shear stress impact vasodilatory capacity. The majority of my doctoral training focused on how alterations to the vascular shear rate profile can improve vascular function within the peripheral and cerebral circulation. The goal of my research is to understand how impairments or improvements within the vasculature relate to quality of life and functional capacity, and the underlying mechanisms that lead to improvements.
brady.hanson@hsc.utah.edu
