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Featured Publications (2017 - 2022)

  1. Tang L, Wu Y, Tian M, Sjostrom CD, Johansson U, Peng XR, Smith DM and Huang Y. Dapagliflozin slows the progression of the renal and liver fibrosis associated with type 2 diabetes. Am J Physiol Endocrinol Metab. 2017, 313: E563-E576. PMID: 28811292 

  1. Hwang J, Huang Y, Burwell TJ, Peterson NC, Connor J, Yu SM and Li Y. Collagen hybridizing peptides for detecting degraded collagen in histopathology. ACS Nano, 2017, 11: 9825-9835, PMID: 28877431. 

  1. Conlin CC, Huang Y, Gordon BAJ, Zhang JL. Quantitative characterization of glomerular fibrosis with magnetic resonance imaging. A feasibility study in a rat glomerulonephritis model. Am J Physiol Renal Physiol. 2018, 314: F747-F752. PMID: 29357425. 

  1. Bamberg K, Johansson U, Edman K, William-Olsson L, Myhre S, Gunnarsson A, Geschwindner S, Aagaard A, Granqvist AB, Jaisser F, Huang Y, Granberg KL, Jansson-Lofmark R, Hartleib-Geschwindner J. Preclinical pharmacology of AZD9977: a novel mineralocorticoid receptor modulator separating organ protection from effects on electrolyte excretion. PLOS One, 2018, 13(2): e0193380, PMID: 29474466.  

  1. Tian M, Tang L, Wu Y, Beddhu S, Huang Y. Adiponectin attenuates kidney injury and fibrosis in deoxycorticosterone acetate-salt and angiotensin II induced CKD mice. Am J Physiol Renal Physiol. 2018, 315: F558-F571, PMID: 29872514. 

  1. Zhou G, Wu J, Gu C, Wang B, Abel ED, Cheung AK, Huang Y. Prorenin independently causes hypertension and renal and cardiac fibrosis in cyp1a1-prorenin transgenic rats. Clin Sci. 2018, 132: 1345-4363. PMID: 29848510, PMCID: PMC6024026 

  1. Zhang Y, Brison AR, Liu T, Huang Y, Carlson NG, Peti-Peterdi J, Kishore BK. Genetic deletion of P2Y2 receptor offers long-term (5 mo) protection against lithium-induced polyuria, natriuresis, kaliuresis, and collecting duct remodeling and cell proliferation. Frontiers in Physiology, 2018, 9: 1765. PMID:30618788. 

  1. Zhang Y, Hansson KM, Liu T, Magnell K, Huang Y, Carlson NG, Kishore BK. Genetic Deletion of ADP-activated P2Y12 Receptor Ameliorates Lithium-induced Nephrogenic Diabetes Insipidus in Mice. Acta Physiol, 2019, 225: e13191. PMID:30257062. 

  1. Liu S, Huang Z, Tang A, Wu X, Aube J, Xu L, Xing C and Huang Y. Inhibition of RNA-binding protein HuR reduces glomerulosclerosis in experimental nephritis. Clin Sci. 2020, 134: 1433-1448. PMID: 32478392. 

  1. Tian M, Carroll LS, Tang L, Uehara H, Westenfelder C, Ambati BK, and Huang Y. Systemic AAV10.COMP-Ang1 rescues renal glomeruli and pancreatic islets in type 2 diabetic mice. BMJ Open Diabetes Res Care. 2020 Aug;8(1): e000882. PMID: 32792355 

  1. Cho M.E., Sweeney C., Fino N., Greene T., Ramkumar N., Huang Y., Ricardo A.C., Shafi T., Deo R., Anderson A., Mills K.T., Cheung A.K., the CRIC Study Investigators. Longitudinal changes in prorenin and renin in renal insufficiency cohort. Am J Nephrol. 2021, 52: 141-451. PMID: 33735863 PMCID: PMC8049970 

  1. Huang Z, Liu S, Tang A, Al-Rabadi L, Hekemeyer M, Mimiche PN, and Huang Y. Key role of EphB2 in renal fibrosis. Clin Sci 2021, 135: 2127-2142. PMID: 34462781, PMCID: PMC8433383 ang Y

  1. Hu C, Beebe K, Hernandez E, Lazaro-Guevara J, Revelo M, Huang Y, Maschek J, Cox J, and Kohan D. Multiomic identification of factors associated with progression to cystic kidney disease in mice with nephron Ift88 disruption. Am J Physiol Renal Physiol, 2022, 322: F175-F192. 

  1. Liu X, Zhang J, Tang A, Xu L and Huang Y. A novel peptide ligand-coated nano-siRNA-lipoplex technology for kidney targeted gene therapy. Am J Transl Res. 2022, July 3 accepted for publication