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The 2013 inaugural keynote address was delivered by Eduardo Marban, MD, PhD of Cedars Sinai Heart Institute, Los Angeles, CA

2013 U-CARS Highlights

Friday, January 18, 2013

 7:00 AM-6:00 PM   Registration

 7:00-8:00 AM         Breakfast

 8:00-8:15 AM         Welcome and Opening Remarks

 8:15-10:15 AM       Session 1: Advances in cardiac remodeling: therapeutic implications

Moderators: Li DY – Kfoury AG 

  • Forward cardiac remodeling and progression of heart failure: do we fully understand it? (Spinale F)
  • Molecular mechanisms of pathological cardiac remodeling (Hill J)
  • Cardiac contractility as a therapeutic target (Movsesian M)
  • Metabolic remodeling in heart failure (Schulze C)

10:15-10:30 AM     Break

10:30-12:00 PM      Session 2: What is myocardial recovery? 10:30-12:00 AM

Moderators: Sanguinetti MC – Gruber PJ

  • Mechanisms of reverse remodeling (Kass DA)
  • Reverse remodeling and functional cardiac recovery: are they synonyms? (Mann D)
  • How to predict and diagnose recovery in the clinic (Givertz M)

12:00-1:00 PM        Lunch - Poster Viewing 

1:00-1:05 PM         Vivian S. Lee, M.D., Ph.D., M.B.A.

Senior Vice President, University Health Sciences

Dean, School of Medicine

CEO, University of Utah Health Systems

Friday, January 18, 2013

1:00-3:00 PM         Session 3: Cardiac recovery lessons 1:00-3:00 PM

Moderators: Spitzer K – Hammond EH

  • Recovery lessons from pharmacological interventions: where do we go from here? (Gilbert EM)
  • Myocarditis-induced myocardial changes: lessons for the recovery field (Miller DV)
  • CRT effects on myocardial function and microstructure: how can this story help the recovery field? (Sachse F)
  • Atrial fibrillation and recovery of the failing heart (Marrouche N)

3:00-3:15 PM         Break  

3:15-4:00 PM         Keynote address  

IntroductionPatel AN    


Eduardo Marban, MD, PhD 

Mark S. Siegal Family Professor

Director, Cedars-Sinai Heart Institute

Los Angeles, CA  USA

“The coming era of regenerative medicine in heart failure: is it really coming?”


4:00-6:00 PM         Session 4: Mechanical Unloading and myocardial recovery (I)

Moderators: Bull DA – Reid BB

  • Mechanical unloading and the failing human heart: atrophy or recovery? (Drakos S)
  • Partial versus complete unloading: what is optimal and when? (Rogers J)
  • Predictors of sustained recovery (Potapov E)