U-CARS 2014

U-CARS 2014 header image

The 2014 keynote address was delivered by Karl Swedberg, MD, PhD of the University of Gothenburg, Sweden.

2014 U-CARS Highlights

FRIDAY, JANUARY 17, 2014

7:00 AM Registration

7:00–8:00 Breakfast

8:00–8:15 Welcome and Opening Remarks

8:15 – 9:45

Session 1: What is myocardial recovery? Chairpersons: James Fang, M.D., Univ. of Utah, Dean Y. Li, M.D./Ph.D., Univ. of Utah

  1. Understanding myocardial recovery: hemodynamic perspective. Daniel Burkhoff, M.D./Ph.D., Columbia University
  2. Understanding myocardial recovery: bridging imaging and metabolism. Eduardo Rame, M.D., Univ. of Pennsylvania
  3. Understanding myocardial recovery: basic science perspective. Kenneth B. Margulies, D., Univ. of Pennsylvania

9:45–10:30

Keynote address Karl Swedberg, M.D./ Ph.D., University of Gothenburg, Sweden Renin angiotensin aldosterone system

and the heart failure syndrome: lessons learned for the cardiac recovery field

10:30–10:45 Break

10:45–12:45

Session 2: Cardiac recovery lessons learned: guidance for future steps Chairpersons: Barry Greenberg, M.D., UCSD, Elizabeth H. Hammond, University of Utah/ Intermountain Healthcare

  1. Recovery lessons from the beta adrenergic system blockade: where do we go from here? Michael Bristow, M.D./Ph.D., Univ. of Colorado
  2. Revascularization leading to myocardial recovery: when and how? Eric Velazquez, M.D., DUKE University
  3. Myocarditis lessons for the cardiac recovery field. Dennis McNamara, D., University of Pittsburgh
  4. Peripartum cardiomyopathy and genetics: what can the recovery field learn? Benjamin D. Horne, Intermountain Healthcare/University of Utah

12:45–1:45 Lunch - Scientific Posters Viewing 1:45–3:15

Session 3: What can we learn from the pediatric world?

Chairpersons: Melanie Everitt, M.D., Primary’s Children’s/ University of Utah, Kevin Whitehead, M.D., University of Utah

 

  1. Biochemical differences in the pediatric failing human heart: why response to treatment and/or recovery may vary from studies of the adult myocardium. Shelley Miyamoto, M.D., Children’s Hospital of Colorado
  2. Achieving myocardial recovery in the child with dilated cardiomyopathy: should we expect it? Jeffrey Towbin, M.D., Cincinnati Children’s Hospital
  3. Ventricular unloading as a means to ventricular recovery in children: for whom will it work and does device matter? Charles
  4. Fraser, M.D., Baylor College of Medicine

3:15–3:30 Break

3:30–5:00

Session 4: Recovering the Right Ventricle: black box or Pandora’s box?

Chairpersons: Stephen Mckellar, M.D., Univ. of Utah, John J. Ryan, M.D., Univ. of Utah

  1. Assessment of RV Function. Ryan Tedford, M.D., Johns Hopkins
  2. How does the RV remodel and compensate in diseased states. Gregory Lewis, M.D., Massachusetts General Hospital
  3. VAD unloading and the right ventricle: do we understand this relationship? Francois Haddad, M.D., Stanford University

6:00–9:00 Symposium Dinner - Best abstract mini oral presentations

 SATURDAY, JANUARY 18, 2014

7:30 Registration

7:30–7:55 Breakfast

7:55–8:00 Opening Remarks

8:00–10:00

Session 5: New therapeutic approaches for myocardial recovery

Chairpersons: Matthew A. Movsesian, M.D., University of Utah, Jared

Rutter, Ph.D., University of Utah

  1. Is heart failure within reach of gene- based therapy? Roger J. Hajjar, M.D., Mount Sinai School of Medicine
  2. Manipulating metabolism to recover the failing Leslie Leinwand, Ph.D., Univ. of Colorado
  3. Optimizing biological therapies for myocardial recovery. Amit Patel, M.D., University of Utah
  4. Inflammation and the Dean Li, M.D./Ph.D., University of Utah

10:00–10:15 Break

10:15–11:45

Session 6: Mechanical circulatory support and cardiac recovery (I)

Chairpersons: Josef Stehlik, M.D., University of Utah, P. Christian Schulze, M.D./Ph.D., Columbia University

  1. Short-term mechanical unloading to recover the acutely failing heart: calcium cycling and other mechanisms. Bartley
  2. Griffith, University of Maryland
  3. INTERMACS 1: How to select patients such that they do well? Francis D. Pagani, M.D./Ph.D., University of Michigan
  4. INTERMACS 1: Recovery therapeutic strategies with an eye to the

bank. Aly El Banayosy, M.D., Penn State College of Medicine

11:45–12:00 Pick Lunch Box 12:00–2:00

Session 7: Mechanical circulatory support

and cardiac recovery (II) Chairpersons: Kenneth Spitzer, Ph.D., University of Utah, Rami Alharethi, M.D., Intermountain Healthcare

  1. Surgical approach to cardiac

O.H. Frazier, Texas Heart Institute

  1. Mechanical unloading and recovery of the failing human heart: the Utah approach. Stavros G. Drakos, University of Utah
  2. Mechanical assist weaning in pediatric patients: Practical considerations. Richard Kirk, M.D., Freeman Hospital/ University of Newcastle, UK
  3. Clinical trials of bridge to recovery: what does the field need to advance? Emma J. Birks, M.D./Ph.D., University of Louisville

2:00–2:15 Break

2:15–3:15

Clinical debate

Chairpersons: Abdallah Kfoury, M.D., Intermountain Healthcare, Jose Nativi, M.D., University of Utah

Case presentation: A donor call for transplanting a 22-year old, advanced idiopathic dilated cardiomyopathy patient 25 days post LVAD implant…

  • ‘Wait before listing such patients – the option of recovery is very attractive’ – Robert Kormos, M.D., University of Pittsburgh
  • ‘Transplant the patient – learn more before establishing recovery in everyday clinical practice’ – Randall Starling, Cleveland Clinic