New Research Grants - October 2017
Marcus G. Pezzolesi, PhD, MPH
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Accelerating Gene Discovery in Diabetic Kidney Disease: An Integrated, 'Big-Data' Approach The goal of this project is to accelerate gene discovery in diabetic kidney disease (DKD) by integrating ‘big-data’ from the Utah Population Database (UPDB) and electronic health records for individuals in the UPDB to identify high-risk families that are enriched for DKD. Data generated as part of this project will be used to guide subsequent whole-genome sequencing-based gene discovery in these families to determine the contribution of variation across the entire genome on renal function decline in DKD. |
Paul J. Shami, MD
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Clinical Development of JS-K for the Treatment of Cancer Dr. Paul Shami and JSK Therapeutics were granted an award from the Small Business Innovation Research Program of the National Cancer Institute to conduct IND-enabling studies of their nitric oxide-generating drug JS-K. JS-K has shown efficacy in animal models of acute myeloid leukemia, multiple myeloma, non-small cell lung cancer and several other solid tumors. Completion of work conducted with this award will allow initiation of Phase I clinical trials of this first-in-class anti-cancer agent. |
