Top Research Publications: April 2021
Note: Names in bold are faculty members in the Department of Internal Medicine.
Cardiovascular Medicine
Hitzeman TC, Xie Y, Zadikany RH, Nikolova AP, Baum R, Xu B, Agvanian S, Melmed GY, McGovern DT, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong TT, Shaw RM. cBIN1 Score (CS) Identifies Ambulatory HFrEF Patients and Predicts Cardiovascular Events. Frontiers in Physiology. 2020 May 25;11:503. doi: 10.3389/fphys.2020.00503. eCollection 2020 PMID: 32670075.
Endocrinology, Metabolism & Diabetes
Wang M-Y, Dean ED, Quittner-Strom E, Zhu Y, Chowdhury KH, Zhang Z, Zhao S, Li N, Ye R, Lee Y, Zhang Y, Chen S, Yu X, Leonard DC, Poffenberger G, Von Dylen A, McCorkle SK, Schlegel A, Sloop KW, Efanov AM, Gimeno RE, Scherer PE, Powers AC, Unger RH, Holland WL (20210222) Glucagon blockade restores functional beta cell mass in type 1 diabetic mice and enhances function of human islets. Proc Natl Acad Sci USA. 2021 Mar 2 118(9) e2022142118.
Sejling A-S, Farhat R, Zhu W, Wang P, Appadurai D, Chan O. Repeated Activation of β2-Adrenergic Receptors in the Ventromedial Hypothalamus Suppresses the Counterregulatory Responses to Hypoglycemia. Endocrinol. 2021 Mar; 162(3):bqaa241. DOI: 10.1210/endocr/bqaa241. Epub 2020 Dec 26. PMID: 33367607.
Ose D, Viskochil R, Holowatyj AN, Larson M, Wilson D, Deshmukh VG, butcher JR, Taylor B, Svoboda K, Leiser J, Tingey B, Haaland B, Wetter DW, Fisher SJ, Hashibe M, Ulrich CM. Understanding the prevalence of prediabetes and diabetes in cancer patients in clinical practice. A real-world cohort study. J Natl Compr Canc Netw. 2021 Mar 10; Online First. doi: 10.6004/jnccn.2020.7653.
Epidemiology
Nelson RE, Byrne TH, Suo Y, Cook J, Pettey W, Gundlapalli AV, Greene T, Gelberg L, Kertesz SG, Tsai J, Montgomery AE. Association of Temporary Financial Assistance With Housing Stability Among US Veterans in the Supportive Services for Veteran Families Program. JAMA Netw Open. 2021 Feb 1;4(2):e2037047. doi: 10.1001/jamanetworkopen.2020.37047. PMID: 33566108.
Martin BI, Brodke DS, Wilson FA, Chaiyakunapruk N, Nelson RE. The Impact of Halting Elective Admissions in Anticipation of a Demand Surge Due to the Coronavirus Pandemic (COVID-19). Med Care. 2021 Mar 1;59(3):213-219. doi: 10.1097/MLR.0000000000001496. PMID: 33427797.
Khader K, Thomas A, Stevens V, Visnovsky L, Nevers M, Toth D, Keegan LT, Jones M, Rubin M, Samore MH. Association Between Contact Precautions and Transmission of Methicillin-Resistant Staphylococcus aureus in Veterans Affairs Hospitals. JAMA Netw Open. 2021 Mar 1;4(3):e210971. doi: 10.1001/jamanetworkopen.2021.0971. PMID: 33720369.
Gastroenterology, Hepatology & Nutrition
Grim C, Noble R, Uribe G, Khanipov K, Johnson P, Koltun WA, Watts T, Fofanov Y, Yochum GS, Powell DW, Beswick EJ, Pinchuk IV. Impairment of tissue resident mesenchymal stem cells in chronic ulcerative colitis and Crohn's disease. J Crohns Colitis. 2021 Jan 28:jjab001. doi: 10.1093/ecco-jcc/jjab001. Online ahead of print. PMID: 33506258.
Kaltenbach T, Gawron A, Meyer CS, Gupta S, Shergill A, Dominitz JA, Soetikno RM, Nguyen-Vu T, Whooley M, Kahi C. Adenoma Detection Rate (ADR) Irrespective of Indication is Comparable to Screening ADR: Implications for Quality Monitoring. Clin Gastroenterol Hepatol. 2021 Feb 19:S1542-3565(21)00206-8. doi: 10.1016/j.cgh.2021.02.028. Online ahead of print. PMID: 33618027.
General Internal Medicine
Bailey RR, Conroy M. Diabetes and obesity are associated with disability in community-dwelling stroke survivors: A cross-sectional study of 37,955 Behavioral Risk Factor Surveillance System respondents. Top Stroke Rehabil. 2021 Mar 28:1-6. doi: 10.1080/10749357.2021.1904537. Epub ahead of print. PMID: 33775239.
Colbert-Getz J, Chow C, Li M, Weber T, Hannon P, Hammad I, Good B, Bonnett R, Sakaeda M, Robson J, Lamb S. Times of Medical Education Crisis Require New Evaluation Approaches: Proof of Concept of a System-Based Program Evaluation Model. Med Sci Educ. 2021 Mar 17:1-6. doi: 10.1007/s40670-021-01271-5. Epub ahead of print. PMID: 33747612; PMCID: PMC7967096.
Johnson SA, Horton DJ, Fuller MJ, Yee J, Aliyev N, Boltax JP, Chambers JH, Lanspa MJ. Patient-Directed Prone Positioning in Awake Patients with COVID-19 Requiring Hospitalization (PAPR). Ann Am Thorac Soc. 2021 Feb 17. doi: 10.1513/AnnalsATS.202011-1466RL. Epub ahead of print. PMID: 33596394.
Hematology & Hematologic Malignancies
Besson C, Moore A, Wu W, Vajdic CM, de Sanjose S, Camp NJ, Smedby KE, Shanafelt TD, Morton LM, Brewer JD, Zablotska L, Engels EA, Cerhan JR, Slager SL, Han J, Berndt SI. Common genetic polymorphisms contribute to the association between chronic lymphocytic leukaemia and non-melanoma skin cancer. Int J Epidemiol. 2021 Mar 22:dyab042. doi: 10.1093/ije/dyab042. Epub ahead of print. PMID: 33748835.
Pomicter AD, Clair PM, Yan D, Heaton WL, Eiring AM, Anderson MB, Richards SM, Gililland J, O'Hare T, Deininger MW. Femoral Heads from Total Hip Arthroplasty as a Source of Adult Hematopoietic Cells. Acta Haematol. 2021 Jan 7:1-7. doi: 10.1159/000511953. Epub ahead of print. PMID: 33412552.
Kim SJ, Song J, Reading NS, Lautersztain J, Kutlar A, Agarwal AM, Coetzer TL, Prchal JT. Novel mechanism of hereditary pyropoikilocytosis phenotype due to co-inheritance of β globin and α spectrin mutations. Am J Hematol. 2021 Feb 8. doi: 10.1002/ajh.26121. Epub ahead of print. PMID: 33556202.
Infectious Diseases
Fox ER, Shah M, Vinik R, Brown S, Buckel W, Webb B, Zarndt J, Evans M, Mesdaghi P, Imlay HN, Spivak ES. Developing statewide remdesivir use criteria. Am J Health Syst Pharm. 2021 Jan 23: zxab009. doi: 10.1093/ajhp/zxab009. Online ahead of print. PMID: 33483744 PMCID: PMC7929409.
Brintz BJ, Haaland B, Howard J, Chao DL, Proctor JL, Khan AI, Ahmed SM, Keegan LT, Greene T, Keita AM, Kotloff KL, Platts-Mills JA, Nelson EJ, Levine AC, Pavia AT, Leung DT. A modular approach to integrating multiple data sources into real-time clinical prediction for pediatric diarrhea. Elfie. 2021 Feb 2; (10): e63009. Doi:10.7554/eLife.63009 PIMD: 33527894 PMCID: PMC7853717.
Nephrology & Hypertension
Pleinis JM, Norrell L, Akella R, Humphreys JM, He H, Sun Q, Zhang F, Sosa-Pagan J, Morrison DE, Schellinger JN, Jackson LK, Goldsmith EJ, Rodan AR. WNKs are potassium-sensitive kinases. Am J Physiol Cell Physiol. 2021 Jan 13. doi: 10.1152/ajpcell.00456.2020. Epub ahead of print. PMID: 33439774.
Oncology
Marron TU, Ryan AE, Reddy SM, Kaczanowska S, Younis RH, Thakkar D, Zhang J, Bartkowiak T, Howard R, Anderson KG, Olson D, Naqash AR, Patel RB, Sachdev E, Rodriguez-Ruiz ME, Sheffer M, Church S, Fuhrman C, Overacre-Delgoffe A, Nguyen R, Florou V, Thaxton JE, Aggen DH, Guerriero JL. Considerations for treatment duration in responders to immune checkpoint inhibitors. J Immunother Cancer. 2021 Mar;9(3):e001901. doi: 10.1136/jitc-2020-01901.PMID: 33653801.
Choi YH, Terry MB, Daly MB, MacInnis RJ, Hopper JL, Colonna S, Buys SS, Andrulis IL, John EM, Kurian AW, Briollais L. Association of Risk-Reducing Salpingo-Oophorectomy With Breast Cancer Risk in Women With BRCA1 and BRCA2 Pathogenic Variants. JAMA Oncol. 2021 Feb 25:e207995. doi: 10.1001/jamaoncol.2020.7995. Online ahead of print. PMID: 33630024.
Denmeade SR, Wang H, Agarwal N, Smith DC, Schweizer MT, Stein MN, Assikis V, Twardowski PW, Flaig TW, Szmulewitz RZ, Holzbeierlein JM, Hauke RJ, Sonpavde G, Garcia JA, Hussain A, Sartor O, Mao S, Cao H, Fu W, Wang T, Abdallah R, Lim SJ, Bolejack V, Paller CJ, Carducci MA, Markowski MC, Eisenberger MA, Antonarakis ES. TRANSFORMER: A Randomized Phase II Study Comparing Bipolar Androgen Therapy Versus Enzalutamide in Asymptomatic Men With Castration-Resistant Metastatic Prostate Cancer. J Clin Oncol. 2021 Feb 22:JCO2002759. doi: 10.1200/JCO.20.02759. Online ahead of print. PMID: 33617303.
Rheumatology
Walsh JA, Magrey M. Clinical Manifestations and Diagnosis of Axial Spondyloarthritis. J Clin Rheumatol. 2020 Oct 22. doi: 10.1097/RHU.0000000000001575. [Epub ahead of print] PMID: 33105312.
Radić M, Overbury RS. Capillaroscopy as a diagnostic tool in the diagnosis of mixed connective tissue disease (MCTD): a case report. BMC Rheumatology. 2021. Mar 19;5(1):9. Doi: 10.1186/s41927-021-00179-2. PMID: 33736700.