Top Research Publications: August 2021
Note: Names in bold are faculty members in the Department of Internal Medicine.
Cardiovascular Medicine
Shankar TS, Ramadurai DKA, Steinhorst K, Sommakia S, Badolia R, Krokidi AT, Calder D, Navankasattusas S, Sander P, Kwon OS, Aravamudhan A, Ling J, Dendorfer A, Xie C, Kwon O, Cheng EHY, Whitehead KJ, Gudermann T, Richardson RS, Sachse FB, Schredelseker J, Spitzer KW, Chaudhuri D, Drakos SG. Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis. Nat Commun. 2021 July 28; 12(4583). Doi.org/10.1038/s41467-021-24869-0.
Endocrinology, Metabolism & Diabetes
Ruf-Zamojski F, Zhang Z, Zamojski M, Smith GR, Mendelev N, Liu H, Nudelman G, Moriwaki M, Pincas H, Castanon RG, Nair VD, Seenarine N, Amper MAS, Zhou X, Ongaro L, Toufaily C, Schang G, Nery JR, Bartlett A, Aldridge A, Jain N, Childs GV, Troyanskaya OG, Ecker JR, Turgeon JL, Welt CK, Bernard DJ, Sealfon SC. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nat Commun. 2021 May 11;12(1):2677. doi: 10.1038/s41467-021-22859-w. PMID: 33976139.
Moriwaki M, Welt CK. PRL Mutation Causing Alactogenesis: Insights Into Prolactin Structure and Function Relationships. J Clin Endocrinol Metab. 2021 Jul 13;106(8):e3021-e3026. doi: 10.1210/clinem/dgab201. PMID: 33770166.
Welt CK. Genetics of Polycystic Ovary Syndrome: What is New? Endocrinol Metab Clin North Am. 2021 Mar;50(1):71-82. doi: 10.1016/j.ecl.2020.10.006. PMID: 22418187.
Epidemiology
Stein BD, Saloner B, Schuler MS, Gurvey J, Sorbero M, Gordon AJ. Concentration of Patient Care Among Buprenorphine-Prescribing Clinicians in the US. JAMA. 2021 Jun 1;325(21):2206-2208. doi: 10.1001/jama.2021.4469. PMID: 34061152; PMCID: PMC8170540.
Pettey WBP, Wagner TH, Rosen AK, Beilstein-Wedel E, Shwartz M, Vanneman ME. Comparing Driving Miles for Department of Veterans Affairs-Delivered Versus Department of Veterans Affairs-purchased Cataract Surgery. Med Care. 2021 Jun 1;59(Suppl 3):S307-S313. doi: 10.1097/MLR.0000000000001491. PMID: 33976081; PMCID: PMC8132907.
Gordon SH, Beilstein-Wedel E, Rosen AK, Zheng T, Kelley AT, Cook J, Zahakos SS, Wagner TH, Vanneman ME. County-Level Predictors of Growth in Community-Based Primary Care Use among Veterans. Med Care. 2021 Jun 1;59(Suppl 3):S301-S306. doi: 10.1097/MLR.0000000000001555. PMID: 33976080; PMCID: PMC8132896.
Gastroenterology, Hepatology & Nutrition
McKenzie P, Fang J, Davis J, Qiu Y, Zhang Y, Adler DG, Gawron AJ. Safety of endoscopist-directed nurse-administered balanced propofol sedation in patients with severe systemic disease (ASA class III). Gastrointest Endosc. 2021 Jul;94(1):124-130. doi: 10.1016/j.gie.2020.11.027. Epub 2020 Dec 10. PMID: 33309879.
Voaklander R, Fang J. Infectious Abscess as Complication of Steroid Injection With Dilation of Refractory Upper Gastrointestinal Strictures. ACG Case Rep J. 2021 Jun 30;8(6):e00619. doi: 10.14309/crj.0000000000000619. eCollection 2021 Jun. PMID: 34250174.
COREOS Collaborators, Ma C, Schoepfer AM, Dellon ES, Bredenoord AJ, Chehade M, Collins MH, Feagan BG, Furuta GT, Gupta SK, Hirano I, Jairath V, Katzka DA, Pai RK, Rothenberg ME, Straumann A, Aceves SS, Alexander JA, Arva NC, Atkins D, Biedermann L, Blanchard C, Cianferoni A, Ciriza de Los Rios C, Clayton F, Davis CM, de Bortoli N, Dias JA, Falk GW, Genta RM, Ghaffari G, Gonsalves N, Greuter T, Hopp R, Hsu Blatman KS, Jensen ET, Johnston D, Kagalwalla AF, Larsson HM, Leung J, Louis H, Masterson JC, Menard-Katcher C, Menard-Katcher PA, Moawad FJ, Muir AB, Mukkada VA, Penagini R, Pesek RD, Peterson K, Putnam PE, Ravelli A, Savarino EV, Schlag C, Schreiner P, Simon D, Smyrk TC, Spergel JM, Taft TH, Terreehorst I, Vanuytsel T, Venter C, Vieira MC, Vieth M, Vlieg-Boerstra B, von Arnim U, Walker MM, Wechsler JB, Woodland P, Woosley JT, Yang GY, Zevit N, Safroneeva E.J Allergy. Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS). Clin Immunol. 2021 Jul 6:S0091-6749(21)01059-9. doi: 10.1016/j.jaci.2021.07.001. Online ahead of print. PMID: 34242635.
General Internal Medicine
Secrest AM, Hopkins ZH, Frost ZE, Taliercio VL, Edwards LD, Biber JE, Chen SC, Chren MM, Ferris LK, Kean J, Hess R; Dermatology PRO Consortium. Quality of Life Assessed Using Skindex-16 Scores Among Patients With Acne Receiving Isotretinoin Treatment. JAMA Dermatol. 2020 Oct 1;156(10):1098-1106. doi: 10.1001/jamadermatol.2020.2330. PMID: 32639529; PMCID: PMC7344833.
Geriatrics
Trott DW, Machin DR, Phuong, TTT, Adeyemo AO, Bloom SI, Bramwell RC, Sorensen ES, Lesniewski LA, Donato AJ. T cells mediate cell non-autonomous arterial aging in mice. J Physiol. 2021. ahead of print.
Hematology & Hematologic Malignancies
López DA, Beaudin AE. Layered immunity of the developing thymus. Blood. 2021 Feb 25;137(8):1003-1004. doi: 10.1182/blood.2020009207. PMID: 33630049; PMCID: PMC7907724.
Montenont E, Bhatlekar S, Jacob S, Kosaka Y, Manne BK, Lee O, Parra-Izquierdo I, Tugolukova E, Tolley ND, Rondina MT, Bray PF, Rowley JW. CRISPR-edited megakaryocytes for rapid screening of platelet gene functions. Blood Adv. 2021 May 11;5(9):2362-2374. doi: 10.1182/bloodadvances.2020004112. PMID: 33944898; PMCID: PMC8114553.
Godara A, Kumar A, Miller KB, Saif MW. Myelodysplastic Syndrome in Patients with Gastro-Pancreatic Malignancies: A Case Series and Review of Literature. Cancer Med J. 2021 Aug 1;4(2):52-59. Epub 2020 Jun 11. PMID: 32685937; PMCID: PMC7367144.
Infectious Diseases
Benamu E, Gajurel K, Anderson JN, Lieb T, Gomez, CA, Seng H, Aquino R, Hollemon D, Hong DK, Blauwkamp TA, Kertesz M, Blair L, Bollyky PL, Medeiros BC, Coutre S, Zompi S, Montoya JG, Deresinski S. Plasma Microbial Cell-free DNA Next Generation Sequencing in the Diagnosis and Management of Febrile Neutropenia. Clin Infect Dis. 2021 Apr 19:ciab324. doi: 10.1093/cid/ciab324. Online ahead of print. PMID: 33870413.
Wahlig TA, Brintz BJ, Prettyman M, Azman AS, Leung DT. A Novel Luminescence-Based Serum Bactericidal Assay for Vibrio cholerae Reduces Assay Variation, Is Time- and Cost-Effective, and Directly Measures Continuous Titer Values. Am J Trop Med Hyg. 2021 Jul 8:tpmd210136. doi: 10.4269/ajtmh.21-0136. Online ahead of print. PMID: 34237020.
Hanson KE, Altayar O, Caliendo A, Arias C, Englund J, Hayden M, Lee M, Loeb M, Patel R, Alayli A, Sultan S, Falck-ytter Y, Lavergne V, Mansour R, Morgan R, Murad H, Patel P, Bhimraj A, Mustafa Reem. The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Antigen Testing. Clin Infect Dis. 2021 Jun 23; ciab557.doi: 10.10093/cid/ciab557. Online ahead of print. PMID: 34160592.
Nephrology & Hypertension
Molnar MZ, Bhalla A, Azhar A, Tsujita M, Talwar M, Balaraman V, Sodhi A, Kadaria D, Eason JD, Hayek SS, Coca SG, Shaefi S, Neyra JA, Gupta S, Leaf DE, Kovesdy CP, STOP-COVID Investigators. Outcomes of critically ill solid organ transplant patients with COVID-19 in the United States. Am J Transplant. 2020 Nov;20(11):3061-3071. doi: 10.1111/ajt.16280. Epub 2020 Sep 15. PMCID: PMC7460925. PMID: 32844546.
Al-Rabadi LF, Caza T, Trivin-Avillach C, Rodan AR, Andeen N, Hayashi N, Williams B, Revelo MP, Clayton F, Abraham J, Lin E, Liou W, Zou CJ, Ramkumar N, Cummins T, Wilkey DW, Kawalit I, Herzog C, Storey A, Edmondson R, Sjoberg R, Yang T, Chien J, Merchant M, Arthur J, Klein J, Larsen C, Beck LH Jr. Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy. J Am Soc Nephrol. 2021 May 5:ASN.2020101395. doi: 10.1681/ASN.2020101395. Epub ahead of print. PMID: 33952630.
Feng Y, Peng K, Luo R, Wang F, Yang T. Site-1 Protease-Derived Soluble (Pro)Renin Receptor Contributes to Angiotensin II-Induced Hypertension in Mice. Hypertension. 2021 Feb;77(2):405-416. doi: 10.1161/HYPERTENSIONAHA.120.15100. Epub 2020 Dec 7. PMCID: PMC7803453. PMID: 33280408.
Oncology
Desai A, Gainor JF, Hegde A, Schram AM, Curigiliano G, Pal S, Liu SV, Halmos B, Groisberg R, Grande E, Dragovich T, Matrana M, Agarwal N, Chawla S, Kato S, Morgan G, Kasi PM, Solomon B, Loong HH, Park H, Choueiri TK, Subbiah IM, Pemmaraju N, Subbiah V; COVID19 and Cancer Clinical Trials Working Group. COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials. Nat Rev Clin Oncol. 2021 Mar 15. doi: 10.1038/s41571-021-00487-z. Online ahead of print. PMID: 33723371.
Florou V, Nevala-Plagemann C, Whisenant J, Maeda P, Gilcrease GW, Garrido-Laguna I. Clinical Activity of Selitrectinib in a Patient With Mammary Analogue Secretory Carcinoma of the Parotid Gland With Secondary Resistance to Entrectinib. J Natl Compr Canc Netw. 2021 May 2;19(5):478-482. doi: 10.6004/jnccn.2021.7022. Print 2021 May. PMID: 34030125.
Nath A, Cosgrove PA, Mirsafian H, Christie EL, Pflieger L, Copeland B, Majumdar S, Cristea MC, Han ES, Lee SJ, Wang EW, Fereday S, Traficante N, Salgia R, Werner T, Cohen AL, Moos P, Chang JT, Bowtell DDL, Bild AH. Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer. Nat Commun. 2021 May 24;12(1):3039. doi: 10.1038/s41467-021-23171-3. PMID: 34031395.
Rheumatology
Miller KL, Steffen MJ, McCoy KD, Cannon G, Seaman AT, Anderson ZL, Patel S, Green J, Wardyn S, Solimeo SL. Delivering fracture prevention services to rural US veterans through telemedicine: a process evaluation. Arch Osteoporos. 2021 Feb 10;16(1):27. doi: 10.1007/s11657-021-00882-0.
Walsh JA, Cai Q, Lin I, Pericone CD, Chakravarty SD. Treatment Persistence and Adherence Among Patients With Psoriatic Arthritis Who Initiated Targeted Immune Modulators in the US: A Retrospective Cohort Study. Adv Ther. 2021 Mar 23. doi: 10.1007/s12325-021-01687-w. [Epub ahead of print]. PMID: 33759081.
Ogdie A, Walsh JA, Chakravarty SD, Peterson S, Lo KH, Kim L, Li N, Hsia EC, Chan EKH, Kavanaugh A, Husni ME. The effect of intravenous golimumab on health-related quality of life and work productivity in patients with active psoriatic arthritis: results of the Phase 3 GO-VIBRANT trial. Clin Rheumatol. 2021 Mar 2. doi: 10.1007/s10067-021-05639-1. [Epub ahead of print]. PMID: 33655380.